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Shengjian Huang
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Journal Articles

Oncogenic MALT1 Promotes Cell Survival and Mediates Ibrutinib Resistance and Ibrutinib-Venetoclax Resistance in Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Junwei Lian, PhD, Shengjian Huang, PhD, Shaojun Zhang, PhD, Yang Liu, PhD, Linghua Wang, MDPhDMS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18.
https://doi.org/10.1182/blood-2020-140871
Published: 2020
Journal Articles

Targeting PI3K and PLK1 to Overcome Ibrutinib-Venetoclax Resistance in Mantle Cell Lymphoma

Changying Jiang, PhD, Rongjia Zhang, Shaojun Zhang, PhD, William Lee, Shengjian Huang, PhD, Yang Liu, MD, Angela Leeming, Joseph Mitchell McIntosh, Preetesh Jain, MBBS,MDDM,PhD, Krystle Nomie, PhD, Linghua Wang, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4062.
https://doi.org/10.1182/blood-2019-128299
Published: 2019
Journal Articles

Pdox Models Empower Preclinical Drug Evaluation and Mechanistic Studies Via Faithful Recapitulation of the Pathology, Complex Heterogeneity, Genetic-Transcriptomic Landscape, and Therapeutic Response of Mantle Cell Lymphoma

Changying Jiang, PhD, Shaojun Zhang, PhD, Shengjian Huang, PhD, Yang Liu, MD, Rongjia Zhang, Angela Leeming, Joseph Mitchell McIntosh, William Lee, Krystle Nomie, PhD, Linghua Wang, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3974.
https://doi.org/10.1182/blood-2019-128810
Published: 2019
Journal Articles

Simultaneous Inhibition of BCL-2 and PI3K Signaling Overcomes Ibrutinib Resistance in Mantle Cell Lymphoma

Haige Ye, PhD MD, Shengjian Huang, PhD, Dayoung Jung, Changying Jiang, PhD, Krystle Nomie, PhD, Liang Zhang, MD PhD, Michael Wang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2950.
https://doi.org/10.1182/blood-2018-99-117013
Published: 2018
Journal Articles

Molecular Pathways Associated with Ibrutinib Resistance in Mantle Cell Lymphoma

Liang Zhang, MD PhD, Krystle Nomie, PhD, Shaojun Zhang, PhD, Yang Liu, MD, Hui Guo, MD PhD, Shengjian Huang, PhD, Jeffrey Wang, Elyse Lopez, Hui Zhang, Elizabeth A Lorence, MPH, Maria Merolle, Swathi Balaji, Makhdum Ahmed, MD MPH, PhD, Changying Jiang, PhD, Linghua Wang, Michael Wang, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2738.
https://doi.org/10.1182/blood.V130.Suppl_1.2738.2738
Published: 2017
Journal Articles

Resistance Mechanisms Underlying Venetoclax Resistance in Mantle Cell Lymphoma

Shengjian Huang, PhD, Changying Jiang, PhD, Hui Guo, MD PhD, Jeffrey Wang, Yang Liu, MD, Carrie Li, Elyse Lopez, Hui Zhang, Elizabeth A Lorence, MPH, Maria Merolle, Swathi Balaji, Makhdum Ahmed, MD MPH, PhD, Krystle Nomie, PhD, Liang Zhang, MD PhD, Michael Wang, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2749.
https://doi.org/10.1182/blood.V130.Suppl_1.2749.2749
Published: 2017
Journal Articles

FoxM1: A New Therapeutic Target for Mantle Cell Lymphoma

Hui Guo, MD PhD, Hui Zhang, Makhdum Ahmed, MD MPH, PhD, Yang Liu, MD, Shengjian Huang, PhD, Victoria Zhang, Jeffrey Wang, Elyse Lopez, Elizabeth A Lorence, MPH, Jacqueline Wang, Swathi Balaji, Merolle Maria, Changying Jiang, PhD, Krystle Nomie, PhD, Michael Wang, BS, Liang Zhang, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1469.
https://doi.org/10.1182/blood.V130.Suppl_1.1469.1469
Published: 2017
Journal Articles

Targeting the Paracaspase MALT1: A Potential Therapy to Overcome Ibrutinib Resistance in Relapsed/Refractory Mantle Cell Lymphoma Patients

Changying Jiang, PhD, Shengjian Huang, PhD, Yang Liu, MD, Carrie Li, Hui Guo, MD PhD, Jeffrey Wang, Elyse Lopez, Hui Zhang, Elizabeth A Lorence, MPH, Maria Merolle, Swathi Balaji, Makhdum Ahmed, MD MPH, PhD, Krystle Nomie, PhD, Xin Lin, PhD, Liang Zhang, MD PhD, Michael Wang, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 574.
https://doi.org/10.1182/blood.V130.Suppl_1.574.574
Published: 2017
Journal Articles

Pre-Clinical Evaluation of the PI3K-p110β/δ Inhibitor KA2237 in Mantle Cell Lymphoma

Shengjian Huang, Loretta J. Nastoupil, MD, Hui Guo, MD PhD, Taylor Bell, Makhdum Ahmed, MD MPH, Carrie J Li, Jack Wang, Yang Liu, PhD, Victoria Zhang, Caroline R Kim, Jordan N Boyle, Elizabeth A Lorence, Laura T Lam, PhD, Zhihong Chen, Hui Zhang, Stephen Joseph Shuttleworth, PhD, Krystle Nomie, PhD, Michael Wang, MD, Liang Zhang, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1837.
https://doi.org/10.1182/blood.V128.22.1837.1837
Published: 2016
Journal Articles

Genetic and Molecular Characterization of Ibrutinib-Resistant Mantle Cell Lymphoma: Designing Innovative Therapeutic Strategies

Hui Guo, MD PhD, Shengjian Huang, Yang Liu, PhD, Carrie J Li, Jack Wang, Victoria Zhang, Makhdum Ahmed, MD MPH, Laura T Lam, PhD, Hui Zhang, Krystle Nomie, PhD, Liang Zhang, MD PhD, Michael Wang, MD
Journal: Blood
Blood (2016) 128 (22): 1838.
https://doi.org/10.1182/blood.V128.22.1838.1838
Published: 2016
Journal Articles

Targeting Oxphos Pathway Against Ibrutinib Resistance to Mantle Cell Lymphoma

Yang Liu, PhD, Taylor Bell, Hui Zhang, Yuting Sun, Carrie J Li, Ningping Feng, PhD, Shengjian Huang, Hui Guo, MD PhD, Jack Wang, Makhdum Ahmed, MD MPH, Victoria Zhang, Laura T Lam, PhD, Krystle Nomie, PhD, Liang Zhang, MD PhD, Maria E Di Francesco, Joe Marszalek, Michael Wang, MD
Journal: Blood
Blood (2016) 128 (22): 290.
https://doi.org/10.1182/blood.V128.22.290.290
Published: 2016
Journal Articles

CUDC-907: An Oral HDAC/PI3K Dual Inhibitor with Strong Preclinical Efficacy in MCL Model

Jordan N Boyle, Caroline R Kim, Hui Guo, MD PhD, Taylor Bell, Shengjian Huang, Carrie J Li, Yang Liu, PhD, Hui Zhang, Jack Wang, Victoria Zhang, Makhdum Ahmed, MD MPH, Laura T Lam, PhD, Krystle Nomie, PhD, Liang Zhang, MD PhD, Dongfeng Zeng, Michael Wang, MD
Journal: Blood
Blood (2016) 128 (22): 4183.
https://doi.org/10.1182/blood.V128.22.4183.4183
Published: 2016