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Journal Articles

Enhanced Hemostatic Efficacy of a Membrane and Factor IXa Binding Antibody Fragment with Cellular Recyclability in Hemophilia Α

Shekhar Kumar, Sriram Krishnaswamy

Blood (2024) 144 (Supplement 1): 427.

https://doi.org/10.1182/blood-2024-210415

Published: 2024

Journal Articles

Design of a Superior Factor VIIIa Mimetic By Coupling a Membrane Binding Domain to a Factor IXa Binding Antibody Fragment

Shekhar Kumar, Sriram Krishnaswamy

Blood (2023) 142 (Supplement 1): 22.

https://doi.org/10.1182/blood-2023-187228

Published: 2023

Journal Articles

X-Ray Structure of Thrombin Bound to a Heterobifunctional Aptamer-Drug Conjugate Reveals the Mechanistic Basis for a Novel Tethered Inhibition Strategy

Shekhar Kumar, Haixiang Yu, Bruce A. Sullenger, Sriram Krishnaswamy

Blood (2022) 140 (Supplement 1): 1668–1669.

https://doi.org/10.1182/blood-2022-163410

Published: 2022

Journal Articles

Structural Basis for the Procofactor to Cofactor Transition in Human Factor V

Shekhar Kumar, PhD, Wei Deng, PhD, Steven Stayrook, PhD, Renhao Li, PhD, Rodney M. Camire, PhD, Sriram Krishnaswamy, PhD

Blood (2016) 128 (22): 253.

https://doi.org/10.1182/blood.V128.22.253.253

Published: 2016

Journal Articles

The X-Ray Structure of a Variant of Human Factor V Provides Structural Insights into the Procofactor Activation Paradox

Shekhar Kumar, PhD, Steven Stayrook, PhD, Rodney M. Camire, PhD, Sriram Krishnaswamy, PhD

Blood (2015) 126 (23): 121.

https://doi.org/10.1182/blood.V126.23.121.121

Published: 2015

Journal Articles

X-Ray Structure of an Anticoagulant RNA Aptamer Bound to Factor Xa. Structural Basis for Its Ability to Disrupt Interactions Between Xa and Va within Prothrombinase

Shekhar Kumar, PhD, Bruce A. Sullenger, PhD, Steven Stayrook, PhD, Sriram Krishnaswamy, PhD

Blood (2014) 124 (21): 4232.

https://doi.org/10.1182/blood.V124.21.4232.4232

Published: 2014

Journal Articles

New Structural Insights into High Affinity Membrane Binding By Coagulation Factor V/Va

Shekhar Kumar, PhD, Steven Stayrook, PhD, James A. Huntington, PhD, Rodney M. Camire, PhD, Sriram Krishnaswamy, PhD

Blood (2014) 124 (21): 4216.

https://doi.org/10.1182/blood.V124.21.4216.4216

Published: 2014

Journal Articles

High Resolution X-Ray Structure of Snake Venom Factor V: Evolution of a Hemostatic Cofactor to a Toxin Poised to Inflict Maximal Damage to Mammalian Blood Coagulation

Shekhar Kumar, PhD, Steven Stayrook, PhD, James A. Huntington, PhD, Rodney M. Camire, PhD, Sriram Krishnaswamy

Blood (2011) 118 (21): 375.

https://doi.org/10.1182/blood.V118.21.375.375

Published: 2011

NARROW

Enhanced Hemostatic Efficacy of a Membrane and Factor IXa Binding Antibody Fragment with Cellular Recyclability in Hemophilia Α

Design of a Superior Factor VIIIa Mimetic By Coupling a Membrane Binding Domain to a Factor IXa Binding Antibody Fragment

X-Ray Structure of Thrombin Bound to a Heterobifunctional Aptamer-Drug Conjugate Reveals the Mechanistic Basis for a Novel Tethered Inhibition Strategy

Structural Basis for the Procofactor to Cofactor Transition in Human Factor V

The X-Ray Structure of a Variant of Human Factor V Provides Structural Insights into the Procofactor Activation Paradox

X-Ray Structure of an Anticoagulant RNA Aptamer Bound to Factor Xa. Structural Basis for Its Ability to Disrupt Interactions Between Xa and Va within Prothrombinase

New Structural Insights into High Affinity Membrane Binding By Coagulation Factor V/Va

High Resolution X-Ray Structure of Snake Venom Factor V: Evolution of a Hemostatic Cofactor to a Toxin Poised to Inflict Maximal Damage to Mammalian Blood Coagulation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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