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Shekhar Krishnan
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Journal Articles

Delayed Intensification Including Venetoclax and Bortezomib Prolongs Survival in Very High Risk Acute Lymphoblastic Leukaemia

Jasmeet Sidhu, Arijit Chakraborty, Parag Das, Manash Pratim Gogoi, Tanima Dey, Fabio D. Steffen, Sangramjit Basu, Debdutta Ganguli, Debjani Ghosh, Niharendu Ghara, Subhajit Kundu, Abhirupa Kar, Beat Bornhauser, Jean-Pierre Bourquin, Vaskar Saha, Shekhar Krishnan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4244.
https://doi.org/10.1182/blood-2023-185989
Published: 2023
Journal Articles

Phenotypic Drug Response Profiling Identifies Asparaginase-Based Synergistic Combinations for Very High Risk Acute Lymphoblastic Leukaemia

Jasmeet Sidhu, Fabio D. Steffen, Iria Anne Jimenez, Yun Huang, Kerstin K. Rauwolf, Arijit Chakraborty, Shekhar Krishnan, Vaskar Saha, Beat Bornhauser, Jean-Pierre Bourquin
Journal: Blood
Blood (2023) 142 (Supplement 1): 417.
https://doi.org/10.1182/blood-2023-172885
Published: 2023
Journal Articles

Adolescent and Young Adult Hodgkin Lymphoma: Is More Better?

Reghu K Sukumaran Nair, MDDCH DM PDF, Vivek S Radhakrishnan, MDDM MSc PDF, Avijeet K Mishra, MBBS MD, Vinay A Guntiboina, MD, Saurabh J Bhave, MDPDF, Jeevan Kumar Garg, MDDNB PDF, Indu Arun, MDPDF, Lateef Zameer, MD, Debdeep Dey, MDFRCPath, Neeraj Arora, MDPDF, Deepak K Mishra, MDPDF, Arpita Bhattacharyya, MRCP, Niharendu Ghara, MDDCH FRCPath, Rimpa B Achari, MD, Shekhar Krishnan, MRCP FRCPath PhD, Mammen Chandy, MDFRCP FRACP FRCPA, Reena Nair, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-142276
Published: 2020
Journal Articles

Metabolic reprogramming of bone marrow stromal cells by leukemic extracellular vesicles in acute lymphoblastic leukemia

Suzanne M. Johnson, Clare Dempsey, Amy Chadwick, Stephanie Harrison, Jizhong Liu, Yujun Di, Owen J. McGinn, Marco Fiorillo, Federica Sotgia, Michael P. Lisanti, Mayur Parihar, Shekhar Krishnan, Vaskar Saha
Journal: Blood
Blood (2016) 128 (3): 453–456.
https://doi.org/10.1182/blood-2015-12-688051
Published: 2016
Journal Articles

Metabolic Reprogramming of Bone Marrow Stromal Cells By Leukemic Extracellular Vesicles in Acute Lymphoblastic Leukemia (ALL)

Suzanne M. Johnson, Clare Dempsey, Amy Chadwick, Stephanie Harrison, Jizhong Liu, Yujun Di, Owen McGinn, Mayur Parihar, Federica Sotgia, Michael Lisanti, Shekhar Krishnan, Vaskar Saha, PhD FRCP, FRCPath
Journal: Blood
Blood (2015) 126 (23): 1430.
https://doi.org/10.1182/blood.V126.23.1430.1430
Published: 2015
Journal Articles

Intramuscular PEG-Asparaginase At 1000 U/m 2 Achieves Adequate Trough Activity Levels in the Majority of Patients Treated on the UKALL 2003 Childhood Acute Lymphoblastic Leukemia (ALL) Protocol

Caroline YK Fong, Catriona Anne Parker, Adiba Hussain, Jizhong Liu, Monika Essink, Hans Juergen Kuehnel, Donna L Lancaster, Genevieve Pridham, Debbie Payne, Charlotte O'Horo, Shekhar Krishnan, Jeremy Hancock, Nicholas Goulden, Anthony V. Moorman, Sue Richards, Ajay J Vora, Vaskar Saha, Ashish Narayan Masurekar
Journal: Blood
Blood (2011) 118 (21): 2573.
https://doi.org/10.1182/blood.V118.21.2573.2573
Published: 2011
Journal Articles

RAC2, AEP, and ICAM1 expression are associated with CNS disease in a mouse model of pre-B childhood acute lymphoblastic leukemia

Mark Holland, Fernanda V. Castro, Seema Alexander, Duncan Smith, Jizhong Liu, Michael Walker, Danny Bitton, Kate Mulryan, Garry Ashton, Morgan Blaylock, Steve Bagley, Yvonne Connolly, John Bridgeman, Crispin Miller, Shekhar Krishnan, Clare Dempsey, Ashish Masurekar, Peter Stern, Anthony Whetton, Vaskar Saha
Journal: Blood
Blood (2011) 118 (3): 638–649.
https://doi.org/10.1182/blood-2010-09-307330
Published: 2011
Includes: Supplemental data
Journal Articles

Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity

Marc N. Offman, Marcin Krol, Naina Patel, Shekhar Krishnan, JiZhong Liu, Vaskar Saha, Paul A. Bates
Journal: Blood
Blood (2011) 117 (5): 1614–1621.
https://doi.org/10.1182/blood-2010-07-298422
Published: 2011
Includes: Supplemental data
Journal Articles

Lymphoblasts Produce a Lysosomal Protease That Rapidly Degrades L-Asparaginase - Implications for Therapy in Childhood Acute Lymphoblastic Leukemia.

Naina Patel, BSc, Shekhar Krishnan, MD, Marc N. Offman, MSc, Cathy X. Moss, PhD, Hany Ariffin, MD, Fred W. vanDelft, MD, Olga Yiannikouris, PhD, Carly Leighton, BSc, Seema Alexander, MSc, Mark Holland, PhD, Doaa Khater, MD, Ji Zhong Liu, MD, PhD, Monika Essink, MD, Paul Bates, PhD, Colin Watts, FRS, Vaskar Saha, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 2791.
https://doi.org/10.1182/blood.V110.11.2791.2791
Published: 2007