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Shad Thaxton, MD, PhD
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Journal Articles

Engineering CpG Deoxynucleotide-Conjugated Gold Nanoparticles for Enhanced Anti-Lymphoma Effects in an Immune Competent Lymphoma Model

Adam Yuh Lin, MD PhD, Jonathan Rink, PhD, Reem Karmali, MD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1577.
https://doi.org/10.1182/blood-2019-125308
Published: 2019
Journal Articles

Bio-Inspired Functional Lipoprotein-like Nanoparticles (Flip-NPs) Cause Cholesterol Starvation and Ferroptosis in B-Cell Lymphomas: Studies in Cell Lines, Xenograft Models and Primary Patient Samples

Jonathan Rink, PhD, Adam Yuh Lin, MD PhD, Shuo Yang, PhD, Amir Behdad, MD, Reem Karmali, MD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2857.
https://doi.org/10.1182/blood-2019-127805
Published: 2019
Journal Articles

Inhibition of Pro-Survival Pathways in DLBCL Cells By Functional Lipoprotein-like Nanoparticles

Jonathan Rink, PhD, Shuo Yang, PhD, Osman Cen, PhD, Reem Karmali, MD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1668.
https://doi.org/10.1182/blood-2018-99-119122
Published: 2018
Journal Articles

Rational Targeting of Cellular Cholesterol in Diffuse Large B-Cell Lymphoma (DLBCL) Enabled By Functional Lipoprotein Nanoparticles and the B Cell Receptor Inhibitor Ibrutinib: A Therapeutic Strategy Dependent on Cell of Origin (COO)

Jonathan Rink, PhD, Osman Cen, PhD, Kaylin Marie McMahon, PhD, Sol Misener, BS, Shuo Yang, PhD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 576.
https://doi.org/10.1182/blood.V130.Suppl_1.576.576
Published: 2017
Journal Articles

High Density Lipoprotein-like Nanoparticles Synergize with Akt and Btk Inhibitors to Induce Cell Death in Diffuse Large B Cell Lymphomas

Jonathan Scott Rink, PhD, Sol Misener, Osman Cen, PhD, Shuo Yang, Leo I. Gordon, MD, Colby Shad Thaxton, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 3022.
https://doi.org/10.1182/blood.V128.22.3022.3022
Published: 2016
Journal Articles

Synthetic High-Density Lipoprotein-like Nanoparticles (HDL NP) Cause Apoptosis and Enhance Killing By B-Cell Receptor and BCL-2 Inhibitors in Chronic Lymphocytic Leukemia (CLL)

Kaylin Marie McMahon, Cristina Scielzo, Lydia Scarfo, Pamela Ranghetti, Shuo Yang, Leo I. Gordon, MD, Frank Giles, MDMB, Colby Shad Thaxton, MD PhD, Paolo Ghia, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2949.
https://doi.org/10.1182/blood.V126.23.2949.2949
Published: 2015
Journal Articles

Biomimetic Synthetic High Density Lipoprotein Nanostructures Target the SR-B1 Receptor and Differentially Manipulate Cellular Cholesterol Flux in Lymphoma Cells: A Novel Treatment Paradigm

Shuo Yang, PhD, Marina G Damiano, BS, Heng Zhang, PhD, Sushant Tripathy, BS, Andrey Ugolkov, MD, PhD, Amareshwar T.K. Singh, PhD, Andrea Luthi, BS, Sandeep S. Dave, MD, MS, Shad Thaxton, MD, PhD, Leo I. Gordon, MD
Journal: Blood
Blood (2012) 120 (21): 157.
https://doi.org/10.1182/blood.V120.21.157.157
Published: 2012
Journal Articles

The Bioactive Polyphenol Curcumin (diferuloylmethane) In Human Apolipoprotein A-1 Nanodisks Enhances Apoptosis and G 1 Cell Cycle Arrest In Mantle Cell Lymphoma Compared with Free Curcumin

Amareshwar T.K. Singh, PhD, Mistuni Ghosh, MS, C. Shad Thaxton, MD, PhD, Trudy M. Forte, PhD, Robert O. Ryan, PhD, Leo I. Gordon, MD, FACP
Journal: Blood
Blood (2010) 116 (21): 3934.
https://doi.org/10.1182/blood.V116.21.3934.3934
Published: 2010