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Journal Articles

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Simone Ragaini, MD, Sarah Wagner, BSc MSc, Giovanni Marconi, Sarah Parisi, MD PhD, Chiara Sartor, MD, Jacopo Nanni, MD, Gianluca Cristiano, Annalisa Talami, MD, Matteo Olivi, MD, Darina Ocadlikova, PhD, Marilena Ciciarello, PhD, Giulia Corradi, PhD, Emanuela Ottaviani, Cristina Papayannidis, Stefania Paolini, MD PhD, Jayakumar Vadakekolathu, PhD, Michele Cavo, Sergio Rutella, MD PhD FRCPath, Antonio Curti, MD PhD

Blood (2019) 134 (Supplement_1): 5193.

https://doi.org/10.1182/blood-2019-128348

Published: 2019

Journal Articles

Adaptive Immune Gene Signatures Correlate with Response to Flotetuzumab, a CD123 × CD3 Bispecific Dart ® Molecule, in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Sergio Rutella, MD PhD FRCPath, Sarah E. Church, PhD, Jayakumar Vadakekolathu, PhD, Elena Viboch, MSc, Amy H Sullivan, BSc, Tressa Hood, MSc, Sarah E. Warren, PhD, Alessandra Cesano, MD PhD, Ross La Motte-Mohs, PhD, John Muth, MS, Helene Lelièvre, PhD PharmD, Bob Lowenberg, MD, John F. DiPersio, MD PhD, Jan K Davidson-Moncada, MD PhD

Blood (2018) 132 (Supplement 1): 444.

https://doi.org/10.1182/blood-2018-99-111539

Published: 2018

Journal Articles

Phase 1 Cohort Expansion of Flotetuzumab, a CD123×CD3 Bispecific Dart ® Protein in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Blood (2018) 132 (Supplement 1): 764.

https://doi.org/10.1182/blood-2018-99-117085

Published: 2018

Journal Articles

Immune Cell Phenotype and Function After Treatment With Blinatumomab For Childhood Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Alice Bertaina, MD, Perla Filippini, BSc MSc, Valentina Bertaina, BSc, Pharm, Barbarella Lucarelli, MD, Aurelie Bauquet, PhD, Gerhard Zugmaier, MD, Franco Locatelli, Sergio Rutella, MD PhD

Blood (2013) 122 (21): 2668.

https://doi.org/10.1182/blood.V122.21.2668.2668

Published: 2013

Journal Articles

Recovery Of Gamma/Delta+ T Cells After Transplantation With Alpha-Beta+/CD19+ Lymphocyte Depleted Hematopoietic Stem Cells From HLA-Haploidentical Donors

Irma Airoldi, PhD, Ignazia Prigione, PhD, Alice Bertaina, MD, Claudia Cocco, PhD, Daria Pagliara, MD, Alessia Zorzoli, Dr., Sergio Rutella, MD, Rita M Pinto, MD, Vito Pistoia, MD, Riccardo Masetti, MD, Mariateresa Romano, MD, Francesca Di Florio, Dr, Francesca Del Bufalo, MD, Lorenzo Moretta, MD, Franco Locatelli

Blood (2013) 122 (21): 3245.

https://doi.org/10.1182/blood.V122.21.3245.3245

Published: 2013

Journal Articles

Removal Of Alpha/Beta+ T Cells and Of CD19+ B Cells From The Graft Translates Into Rapid Engraftment, Absence Of Visceral Graft-Versus-Host Disease and Low Transplant-Related Mortality In Children With Acute Leukemia Given HLA-Haploidentical Hematopoietic Stem Cell Transplantation

Blood (2013) 122 (21): 157.

https://doi.org/10.1182/blood.V122.21.157.157

Published: 2013

Journal Articles

Indoleamine 2,3-Dioxygenase-1 (IDO1) Is Expressed by a Subset of Childhood Acute Myeloid Leukemias and Restrains IFN-γ Production by T Cells

Valentina Folgiero, BSc, Daniela Natale, BSc, Daria Pagliara, MD, Roberta Caruso, MD, Luciana Vinti, MD, Valentina Coletti, MD, Francesca Moretta, MD, Raimondo De Cristofaro, MD, Franco Locatelli, MD, PhD, Sergio Rutella, MD PhD

Blood (2012) 120 (21): 1430.

https://doi.org/10.1182/blood.V120.21.1430.1430

Published: 2012

Journal Articles

Negative Depletion of B Cells and T Cells Expressing the αβ Chain of the T-Cell Receptor (TCR) for Haploidentical Stem Cell Transplantation

Giuseppina Li Pira, BSc, Fabiola Landi, MD, Perla Filippini, BSc MSc, Paola Giustiniani, BSc, Alice Bertaina, MD, Daria Pagliara, MD, Rita M Pinto, MD, Katia Girardi, MD, Giovanna Del Principe, MD, Stefano Ceccarelli, MD, Franco Locatelli, MD, PhD, Sergio Rutella, MD, PhD

Blood (2012) 120 (21): 343.

https://doi.org/10.1182/blood.V120.21.343.343

Published: 2012

Journal Articles

HLA Haploidentical Stem Cell Transplantation After Removal of αβ + T Lymphocytes and B Lymphocytes Is an Effective Treatment for Children with Life-Threatening, Non-Malignant Disorders

Alice Bertaina, MD, Mariateresa Romano, MD, Sergio Rutella, MD PhD, Giuseppe Palumbo, MD, Daria Pagliara, MD, Stefano Ceccarelli, MD, Letizia P Brescia, MD, Giuseppina Li Pira, BSc, Francesca Cocca, MD, Maria Ester Bernardo, MD, Giuseppe M Milano, MD, Daniela Pende, PhD, Michela Falco, BSc, Lorenzo Moretta, MD, Franco Locatelli, MD, PhD

Blood (2012) 120 (21): 2018.

https://doi.org/10.1182/blood.V120.21.2018.2018

Published: 2012

Journal Articles

Favorable Outcome of Children with Acute Megakaryoblastic Leukemia Treated with the AIEOP AML 2002/01 Protocol

Franco Locatelli, Maria Caterina Putti, Andrea Pession, Prof, MD, Franca Fagioli, MD, Giuseppe Menna, Concetta Micalizzi, Carmelo Rizzari, MD, PhD, Sergio Rutella, MD PhD, Andrea Biondi, MD, Barbara Buldini, Riccardo Masetti, MD, Giuseppe Basso

Blood (2012) 120 (21): 3586.

https://doi.org/10.1182/blood.V120.21.3586.3586

Published: 2012

Journal Articles

Interleukin-21 Induces the Differentiation of Human Umbilical Cord Blood CD34. − lineage − Cells Into Pseudomature Lytic NK Cells.

Giuseppina Bonanno, BSc, Maria Corallo, BSc, Annabella Procoli, BSc, Andrea Mariotti, BSc, Luca Pierelli, MD, Giovanni Scambia, MD, Sergio Rutella, MD, PhD

Blood (2009) 114 (22): 1476.

https://doi.org/10.1182/blood.V114.22.1476.1476

Published: 2009

Journal Articles

Indoleamine 2,3-Dioxygenase Is Expressed and Functionally Active in Human Dermal Dendritic Cells, but Not in Epidermal Langherans Cells.

Antonio Curti, Sara Trabanelli, Darina Ocadlikova, MSc, Sergio Rutella, MD, PhD, Raimondo De Cristofaro, MD, Michele Baccarani, MD, Roberto M Lemoli

Blood (2009) 114 (22): 278.

https://doi.org/10.1182/blood.V114.22.278.278

Published: 2009

Journal Articles

Functional IDO Is Expressed on CD34 + - and Monocyte-Derived Dendritic Cells According to Differentiation Status.

Antonio Curti, Sara Trabanelli, Chiara Onofri, Sergio Rutella, MD, PhD, Raimondo De Cristofaro, MD, Michele Baccarani, Roberto M Lemoli

Blood (2008) 112 (11): 1552.

https://doi.org/10.1182/blood.V112.11.1552.1552

Published: 2008

Journal Articles

Indoleamine 2,3-Dioxygenase (IDO) Is Expressed by Multiple Myeloma Plasma Cells and Promotes the Differentiation of Regulatory T Cells: Investigations into the Role of Hepatocyte Growth Factor.

Giuseppina Bonanno, BSc, Maria Corallo, BSc, Andrea Mariotti, BSc, Anna Di Maggio, BSc, Annabella Procoli, BSc, Luca De Rosa, MD, Luca Pierelli, MD, Ignazio Majolino, MD, Giuseppe Leone, MD, Raimondo De Cristofaro, MD, Sergio Rutella, MD, PhD

Blood (2008) 112 (11): 1680.

https://doi.org/10.1182/blood.V112.11.1680.1680

Published: 2008

Journal Articles

The Fibrinogen Elongated γ-Chain Inhibits Thrombin-Induced Platelet Response, Hindering the Interaction with Different Receptors.

Stefano Lancellotti, BSc, Sergio Rutella, MD, PhD, Vincenzo De Filippis, PhD, Nicola Pozzi, PhD, Bianca C Rocca, MD, PhD, Raimondo De Cristofaro, MD

Blood (2008) 112 (11): 2023.

https://doi.org/10.1182/blood.V112.11.2023.2023

Published: 2008

Journal Articles

COX-2 Inhibition Suppresses the Interferon-γ-Induced Expression of Indoleamine 2,3-Dioxygenase (IDO) in Human Leukemia Cell Lines.

Maria Grazia Iachininoto, BSc, Eugenia Rosa Nuzzolo, BSc, Anna Di Maggio, BSc, Giuseppina Bonanno, BSc, Andrea Mariotti, BSc, Annabella Procoli, BSc, Maria Corallo, BSc, Giuseppe Leone, MD, Raimondo De Cristofaro, MD, Sergio Rutella, MD, PhD

Blood (2008) 112 (11): 1623.

https://doi.org/10.1182/blood.V112.11.1623.1623

Published: 2008

Journal Articles

Interleukin (IL)-21 in Combination with IL-15 Induces the Differentiation of Human Umbilical Cord Blood CD34 − Lineage − Cells into Pseudomature Lytic NK Cells.

Giuseppina Bonanno, BSc, Annabella Procoli, BSc, Andrea Mariotti, BSc, Maria Corallo, BSc, Giovanni Scambia, MD, Luca Pierelli, MD, Giuseppe Leone, MD, Sergio Rutella, MD, PhD

Blood (2007) 110 (11): 4031.

https://doi.org/10.1182/blood.V110.11.4031.4031

Published: 2007

Journal Articles

Hepatocyte Growth Factor (HGF) Favors Monocyte Differentiation into Interleukin (IL)-10 + IL-12 neg Regulatory Dendritic Cells.

Sergio Rutella, MD, PhD, Giuseppina Bonanno, BSc, Annabella Procoli, BSc, Andrea Mariotti, BSc, Nathalie Saulnier, BSc, Antonio Curti, MD, Giuseppe Leone, MD, Roberto M. Lemoli, MD

Blood (2005) 106 (11): 2297.

https://doi.org/10.1182/blood.V106.11.2297.2297

Published: 2005

Journal Articles

Leukemic Transformation Induces the Constitutive Expression of Indoleamine 2,3-Dyoxigenase Which Directly Increases CD4 + CD25 + T Regulatory Cells.

Antonio Curti, MD, Simona Pandolfi, BS, Michela Aluigi, BS, Barbara Valzasina, BS, Alessandro Isidori, MD, Elisa Ferri, BS, Sergio Rutella, MD, Ilaria Durelli, BS, Alberto L. Horenstein, MD, Francesca Fiore, MD, Massimo Massaia, MD, Milena Piccioli, BS, Emanuela Palmerini, MD, Stefano Pileri, MD, Mario P. Colombo, BS, Michele Baccarani, MD, Roberto M. Lemoli, MD

Blood (2005) 106 (11): 1210.

https://doi.org/10.1182/blood.V106.11.1210.1210

Published: 2005

Journal Articles

Gentuzumab-Ozogamicin,Citosine Arabinoside, G-CSF Combination in the Treatment of Elderly Poor Prognosis Acute Myeloid Leukemia. A Multicentric Study.

Luana Fianchi, MD, Franco Leoni, MD, Sergio Storti, MD, Sergio Rutella, MD, Giacomo Gianfaldoni, MD, Maria Teresa Voso, MD, Stefano Bosi, MD, Livio Pagano, MD, Giuseppe Leone, MD

Blood (2005) 106 (11): 4604.

https://doi.org/10.1182/blood.V106.11.4604.4604

Published: 2005

NARROW

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Adaptive Immune Gene Signatures Correlate with Response to Flotetuzumab, a CD123 × CD3 Bispecific Dart ® Molecule, in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Phase 1 Cohort Expansion of Flotetuzumab, a CD123×CD3 Bispecific Dart ® Protein in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Immune Cell Phenotype and Function After Treatment With Blinatumomab For Childhood Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Recovery Of Gamma/Delta+ T Cells After Transplantation With Alpha-Beta+/CD19+ Lymphocyte Depleted Hematopoietic Stem Cells From HLA-Haploidentical Donors

Removal Of Alpha/Beta+ T Cells and Of CD19+ B Cells From The Graft Translates Into Rapid Engraftment, Absence Of Visceral Graft-Versus-Host Disease and Low Transplant-Related Mortality In Children With Acute Leukemia Given HLA-Haploidentical Hematopoietic Stem Cell Transplantation

Indoleamine 2,3-Dioxygenase-1 (IDO1) Is Expressed by a Subset of Childhood Acute Myeloid Leukemias and Restrains IFN-γ Production by T Cells

Negative Depletion of B Cells and T Cells Expressing the αβ Chain of the T-Cell Receptor (TCR) for Haploidentical Stem Cell Transplantation

HLA Haploidentical Stem Cell Transplantation After Removal of αβ + T Lymphocytes and B Lymphocytes Is an Effective Treatment for Children with Life-Threatening, Non-Malignant Disorders

Favorable Outcome of Children with Acute Megakaryoblastic Leukemia Treated with the AIEOP AML 2002/01 Protocol

Interleukin-21 Induces the Differentiation of Human Umbilical Cord Blood CD34. − lineage − Cells Into Pseudomature Lytic NK Cells.

Indoleamine 2,3-Dioxygenase Is Expressed and Functionally Active in Human Dermal Dendritic Cells, but Not in Epidermal Langherans Cells.

Functional IDO Is Expressed on CD34 + - and Monocyte-Derived Dendritic Cells According to Differentiation Status.

Indoleamine 2,3-Dioxygenase (IDO) Is Expressed by Multiple Myeloma Plasma Cells and Promotes the Differentiation of Regulatory T Cells: Investigations into the Role of Hepatocyte Growth Factor.

The Fibrinogen Elongated γ-Chain Inhibits Thrombin-Induced Platelet Response, Hindering the Interaction with Different Receptors.

COX-2 Inhibition Suppresses the Interferon-γ-Induced Expression of Indoleamine 2,3-Dioxygenase (IDO) in Human Leukemia Cell Lines.

Interleukin (IL)-21 in Combination with IL-15 Induces the Differentiation of Human Umbilical Cord Blood CD34 − Lineage − Cells into Pseudomature Lytic NK Cells.

Hepatocyte Growth Factor (HGF) Favors Monocyte Differentiation into Interleukin (IL)-10 + IL-12 neg Regulatory Dendritic Cells.

Leukemic Transformation Induces the Constitutive Expression of Indoleamine 2,3-Dyoxigenase Which Directly Increases CD4 + CD25 + T Regulatory Cells.

Gentuzumab-Ozogamicin,Citosine Arabinoside, G-CSF Combination in the Treatment of Elderly Poor Prognosis Acute Myeloid Leukemia. A Multicentric Study.

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American Society of Hematology

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American Society of Hematology

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