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Journal Articles

Effects of Andexanet Alfa on Thrombin Generation in Bleeding Associated with Factor Xa Inhibitors

Michiel Coppens, MD, Lizhen Xu, PhD, Roisin Bavalia, MD, Saskia Middeldorp, MD PhD, Peter Verhamme, MD PhD, John W. Eikelboom, MBBS, MSc, FRACP, FRCPA, Mark Crowther, MD, Genmin Lu, Patrick Yue, MD, Pamela B. Conley, PhD, Stuart J. Connolly, MD MSc, FRCPC

Blood (2019) 134 (Supplement_1): 711.

https://doi.org/10.1182/blood-2019-124596

Published: 2019

Journal Articles

Safety and Efficiency of the YEARS Diagnostic Algorithm for Pregnant Patients with Clinically Suspected Acute Pulmonary Embolism —the Artemis Study

Liselotte M. Van Der Pol, MD, Cecile Tromeur, Ingrid Bistervels, MD, Thomas van Bemmel, Francis Couturaud, MD PhD, Laura M. Faber, Albert T.A. Mairuhu, Saskia Middeldorp, MD PhD, Marije ten Wolde, Erik A Klok, MD PhD, Menno V. Huisman

Blood (2018) 132 (Supplement 1): 419.

https://doi.org/10.1182/blood-2018-99-113336

Published: 2018

Journal Articles

A Plasma-Based Assay to Measure the Susceptibility of Factor V(a) to Inhibition By TFPIα

Tilman M. Hackeng, PhD, Peter van Doorn, MSc, Jan Rosing, PhD, Joost Meijers, PhD, Saskia Middeldorp, MD PhD, Paolo Simioni, MD PhD, Elisabetta Castoldi, PhD

Blood (2018) 132 (Supplement 1): 1168.

https://doi.org/10.1182/blood-2018-99-118767

Published: 2018

Journal Articles

Elevated Levels of Circulating Nucleosomes Are Not Associated with Venous Thrombosis or Neutrophil Activation in Patients with Multiple Myeloma

Mandy N. Lauw, MD PhD, Frank W.G. Leebeek, MD PhD, Moniek P.M. de Maat, PhD, Gerard J. van Mierlo, Saskia Middeldorp, MD PhD, Sacha S. Zeerleder, MD PhD

Blood (2016) 128 (22): 274.

https://doi.org/10.1182/blood.V128.22.274.274

Published: 2016

Journal Articles

Interm Report of the Highlow Study: A Randomized Controlled Trial Comparing Two Doses of Low Molecular Weight Heparin for the Prevention of Pregnancy-Associated Recurrent Venous Thromboembolism

Suzanne M Bleker, MD, Bistervels M Ingrid, MD, Andrea Buchmüller, Céline Chauleur, Fionnuala Ní Áinle, MD PhD, Jennifer Donnelly, Peter Verhamme, Anne Flem Jacobsen, Hervé Décousus, Saskia Middeldorp, MD PhD

Blood (2016) 128 (22): 1444.

https://doi.org/10.1182/blood.V128.22.1444.1444

Published: 2016

Journal Articles

Circulating Activated Protein C in Thrombophilia Carriers

Thijs E van Mens, MD MBA, Joost C.M. Meijers, PhD Professor, Saskia Middeldorp, MD PhD Professor of MDcine

Blood (2016) 128 (22): 4948.

https://doi.org/10.1182/blood.V128.22.4948.4948

Published: 2016

Journal Articles

The Performance of the Original and Simplified Wells Scores in Combination with Age-Adjusted D-Dimer Testing in the Diagnostic Management of Pulmonary Embolism

Noémie Kraaijpoel, MSc, Nick van Es, MD, Harry R Büller, MD PhD, Frederikus A Klok, MD PhD, Menno V Huisman, Paul L den Exter, MD PhD, Javier Galipienzo, MD PhD, Saskia Middeldorp, MD PhD, Patrick M Bossuyt, PhD

Blood (2016) 128 (22): 2569.

https://doi.org/10.1182/blood.V128.22.2569.2569

Published: 2016

Journal Articles

Clinical Impact and Course of Anticoagulant-Related Major Bleeding in Cancer Patients

Noémie Kraaijpoel, MSc, Nick van Es, MD, Suzanne M Bleker, MD, Marjolein P Brekelmans, MD, Elise S Eerenberg, MD, Saskia Middeldorp, MD PhD Professor of MDcine, Alexander T Cohen, MBBS MSc MD, Harry R Büller, MD PhD

Blood (2016) 128 (22): 2611.

https://doi.org/10.1182/blood.V128.22.2611.2611

Published: 2016

Journal Articles

Low Molecular Weight Heparin for Prevention of Placenta-Mediated Pregnancy Complications: An Individual Patient Data Meta-Analysis

Blood (2015) 126 (23): 890.

https://doi.org/10.1182/blood.V126.23.890.890

Published: 2015

Journal Articles

A New Microparticle Coagulant Activity Assay to Predict Venous Thromboembolism in Patients with Pancreatic Cancer

Nick van Es, MD, Suzanne Bleker, MD, Ankie Kleinjan, MDPhD, Rene Berckmans, PhD, J W Wilmink, MDPhD, Rienk Nieuwland, PhD, Saskia Middeldorp, MD PhD, Harry R Büller, MD PhD

Blood (2014) 124 (21): 4250.

https://doi.org/10.1182/blood.V124.21.4250.4250

Published: 2014

Journal Articles

Towards Successful Implementation of Pharmacokinetic-Guided Prophylactic Dosing of Clotting Factor Concentrate in Hemophilia; The Do’s and Don’ts after Discrete Choice Experiment Analysis

Janske Lock, MD PhDstudent, Esther W. de Bekker-Grob, PhD, Gamze Urhan, MD, Saskia Middeldorp, MD PhD, Marjolein Peters, MD PhD, Karina Meijer, MD PhD, Rienk Y.J. Tamminga, MD PhD, Britta Laros-van Gorkum, MD PhD, Paul Brons, Felix J.M. Van der Meer, MD PhD, Mariette H.E. Driessens, PhD, Peter W. Collins, MD, Karin Fijnvandraat, MD PhD, Frank W.G. Leebeek, MD PhD, Marjon H. Cnossen, MD PhD

Blood (2014) 124 (21): 5038.

https://doi.org/10.1182/blood.V124.21.5038.5038

Published: 2014

Journal Articles

Unsuspected Pulmonary Embolism in Cancer Patients: A Multicenter, International, Prospective, Observational Study

Suzanne Bleker, MD, Nick van Es, MD, Ankie Kleinjan, MD PhD, Harry R. Büller, MD PhD, Saskia Middeldorp, MD PhD, Marcello Dinisio, MD PhD

Blood (2014) 124 (21): 1546.

https://doi.org/10.1182/blood.V124.21.1546.1546

Published: 2014

Journal Articles

Circulating Nucleosomes and Neutrophil Activation As Risk Factors for Deep Vein Thrombosis

Maurits L van Montfoort, MD, Femke Stephan, Mandy N Lauw, MD, Barbara A Hutten, PhD, Gerard J van Mierlo, Shabnam Solati, Saskia Middeldorp, MD, PhD, Joost CM Meijers, PhD, Sacha S Zeerleder, MD, PhD

Blood (2012) 120 (21): 3387.

https://doi.org/10.1182/blood.V120.21.3387.3387

Published: 2012

Journal Articles

High Levels of Protein C Are Determinated by PROCR H3 in a Dutch Family.

Maria Carolina Pintao, MD, Sara Roshani, Marieke C.H. de Visser, MD, PhD, Cris Tieken, Michael W.T. Tanck, PhD, Harry Roger Buller, MD, PhD, Iris M Wichers, Joost C.M. Meijers, PhD, Saskia Middeldorp, MD, PhD, Pieter H. Reitsma, PhD

Blood (2009) 114 (22): 2139.

https://doi.org/10.1182/blood.V114.22.2139.2139

Published: 2009

Journal Articles

Associations Between Free Protein S and Factor VIII Levels with Traditional Arterial Thrombotic Risk Factors and Their Risk On Arterial Thrombosis. Results From a Retrospective Family Cohort Study.

René Mulder, Inge M van Schouwenburg, Bakhtawar Khan Mahmoodi, Nic J.G.M. Veeger, André B Mulder, MD, Saskia Middeldorp, MD, PhD, Hanneke C. Kluin-Nelemans, Willem M Lijfering, MD

Blood (2009) 114 (22): 25.

https://doi.org/10.1182/blood.V114.22.25.25

Published: 2009

Journal Articles

Thrombophilia and Cardiovascular Risk Factors On the Absolute Risk of First and Recurrent Venous Thrombosis. Results From a Retrospective Family Cohort Study Involving 2097 Relatives.

Anja B.U. MÄkelburg, MD, Saskia Middeldorp, MD, PhD, Karly Hamulyàk, MD, PhD, Martin Prins, MD, PhD, Harry R Büller, MD, PhD, Willem M. Lijfering, MD, PhD

Blood (2009) 114 (22): 2974.

https://doi.org/10.1182/blood.V114.22.2974.2974

Published: 2009

Journal Articles

Aspirin and Aspirin Combined with Low-Molecular-Weight Heparin in Women with Unexplained Recurrent Miscarriage: a Randomized Controlled Multicenter Trial (ALIFE Study).

Stef P. Kaandorp, MD, Mariëtte Goddijn, MD, PhD, Joris A.M. van der Post, MD, PhD, Barbara A. Hutten, PhD, Harold R. Verhoeve, MD, Karly Hamulyak, MD, PhD, Ben-Willem Mol, MD, PhD, Nienke Folkeringa, MD, PhD, Marleen Nahuis, MD, Dimitri Papatsonis, MD, PhD, Harry R. Buller, MD, PhD, Fulco van der Veen, MD, PhD, Saskia Middeldorp, MD, PhD

Blood (2009) 114 (22): 488.

https://doi.org/10.1182/blood.V114.22.488.488

Published: 2009

Journal Articles

Increased Sperm Count Maintains High Population Frequency of Factor V Leiden.

Danny M Cohn, MD, Sjoerd Repping, MD, PhD, Harry R Büller, MD, PhD, Joost CM Meijers, PhD, Saskia Middeldorp, MD, PhD

Blood (2009) 114 (22): 3994.

https://doi.org/10.1182/blood.V114.22.3994.3994

Published: 2009

Journal Articles

Recurrent Miscarriage in Women with and without Antiphospholipid Syndrome: Prognosis and Predictors of a Subsequent Successful Delivery.

Danny M Cohn, MD, Saskia Middeldorp, MD, PhD, Johanna C Korevaar, PhD, Feroza Dawood, Harry R Büller, MD, PhD, Mariëtte Goddijn, MD, PhD, Roy Farquharson, MD, FRCOG

Blood (2009) 114 (22): 2971.

https://doi.org/10.1182/blood.V114.22.2971.2971

Published: 2009

Journal Articles

No Difference in Risk of Recurrent Venous Thrombosis between Men and Women. Results from a Family Cohort Study in 3356 Subjects.

Willem M. Lijfering, MD, Michiel Coppens, MD, Nic J.G.M. Veeger, MSc, Saskia Middeldorp, MD, PhD, Karly Hamulyak, MD, PhD, Martin H. Prins, MD, Phd, Harry R. Buller, MD, PhD, Jan van der Meer, Md, PhD

Blood (2007) 110 (11): 130.

https://doi.org/10.1182/blood.V110.11.130.130

Published: 2007

NARROW

Effects of Andexanet Alfa on Thrombin Generation in Bleeding Associated with Factor Xa Inhibitors

Safety and Efficiency of the YEARS Diagnostic Algorithm for Pregnant Patients with Clinically Suspected Acute Pulmonary Embolism —the Artemis Study

A Plasma-Based Assay to Measure the Susceptibility of Factor V(a) to Inhibition By TFPIα

Elevated Levels of Circulating Nucleosomes Are Not Associated with Venous Thrombosis or Neutrophil Activation in Patients with Multiple Myeloma

Interm Report of the Highlow Study: A Randomized Controlled Trial Comparing Two Doses of Low Molecular Weight Heparin for the Prevention of Pregnancy-Associated Recurrent Venous Thromboembolism

Circulating Activated Protein C in Thrombophilia Carriers

The Performance of the Original and Simplified Wells Scores in Combination with Age-Adjusted D-Dimer Testing in the Diagnostic Management of Pulmonary Embolism

Clinical Impact and Course of Anticoagulant-Related Major Bleeding in Cancer Patients

Low Molecular Weight Heparin for Prevention of Placenta-Mediated Pregnancy Complications: An Individual Patient Data Meta-Analysis

A New Microparticle Coagulant Activity Assay to Predict Venous Thromboembolism in Patients with Pancreatic Cancer

Towards Successful Implementation of Pharmacokinetic-Guided Prophylactic Dosing of Clotting Factor Concentrate in Hemophilia; The Do’s and Don’ts after Discrete Choice Experiment Analysis

Unsuspected Pulmonary Embolism in Cancer Patients: A Multicenter, International, Prospective, Observational Study

Circulating Nucleosomes and Neutrophil Activation As Risk Factors for Deep Vein Thrombosis

High Levels of Protein C Are Determinated by PROCR H3 in a Dutch Family.

Associations Between Free Protein S and Factor VIII Levels with Traditional Arterial Thrombotic Risk Factors and Their Risk On Arterial Thrombosis. Results From a Retrospective Family Cohort Study.

Thrombophilia and Cardiovascular Risk Factors On the Absolute Risk of First and Recurrent Venous Thrombosis. Results From a Retrospective Family Cohort Study Involving 2097 Relatives.

Aspirin and Aspirin Combined with Low-Molecular-Weight Heparin in Women with Unexplained Recurrent Miscarriage: a Randomized Controlled Multicenter Trial (ALIFE Study).

Increased Sperm Count Maintains High Population Frequency of Factor V Leiden.

Recurrent Miscarriage in Women with and without Antiphospholipid Syndrome: Prognosis and Predictors of a Subsequent Successful Delivery.

No Difference in Risk of Recurrent Venous Thrombosis between Men and Women. Results from a Family Cohort Study in 3356 Subjects.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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