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Sarah Skuli
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Journal Articles

Pitavastatin Potentiates Mitochondrial Dysfunction and Venetoclax Cytotoxicity in Acute Myeloid Leukemia Cells

Madhuri Paul, Roberta Buono, Dennis Juarez, Ian Benjamin Wong, Sarah Skuli, Martin P Carroll, David A Fruman
Journal: Blood
Blood (2024) 144 (Supplement 1): 5813.
https://doi.org/10.1182/blood-2024-210777
Published: 2024
Journal Articles

Multi-Omic Analyses of TP53 -Mutated Acute Myeloid Leukemia Identify Prognostic Metabolic Signatures

Jayakumar Vadakekolathu, Sarah Skuli, David J Boocock, Clare Coveney, Eruchi G Ikpo, Bofei Wang, Elena M Fenu, Hussein A. Abbas, Catherine E. Lai, Martin P Carroll, Sergio Rutella
Journal: Blood
Blood (2024) 144 (Supplement 1): 2911.
https://doi.org/10.1182/blood-2024-201311
Published: 2024
Journal Articles

The Mevalonate Pathway Is a Therapeutic Target in TP53 Mutant Acute Myeloid Leukemia

Sarah Skuli, A'Ishah Bakayoko, Gerald Wertheim, Owen Riley, Marisa Kruidenier, Bryan Manning, Akmal Salimov, Gisela Brake-Silla, Derek Dopkin, Jimmy Xu, Eva Nee, Lorelai Mesaros, Ryan Hausler, Manuela Lavorato, Eiko Ogiso, Marni Falk, Kara Maxwell, Nicolas Skuli, Clementina Mesaros, Martin Carroll
Journal: Blood
Blood (2023) 142 (Supplement 1): 408.
https://doi.org/10.1182/blood-2023-185059
Published: 2023
Journal Articles

Transcriptomic without Clinical Response to Menin Inhibition As a Mechanism of Upfront Resistance in Samples from Mutliply Relapsed Patients with KMT2A-Rearranged Leukemia

Leila Mahdavi, Haley Goodrow, Hongbo Xie, Alexandra Lenard, Fatemeh Alikarami, Simone Stefanie Riedel, Sarah K. Tasian, Gerald Wertheim, Sarah Skuli, Martin Carroll, Jerry McGeehan, Kathrin M. Bernt
Journal: Blood
Blood (2023) 142 (Supplement 1): 4166.
https://doi.org/10.1182/blood-2023-180967
Published: 2023
Journal Articles

NAMPT Haploinsufficiency Is a Therapeutic Vulnerability in High-Risk Myeloid Malignancies

Madhavi D. Senagolage, Saira Khan, Sarah Skuli, Martin Carroll, Megan E. McNerney
Journal: Blood
Blood (2023) 142 (Supplement 1): 5753.
https://doi.org/10.1182/blood-2023-191061
Published: 2023
Journal Articles

Real World Effectiveness of "7 + 3" Intensive Chemotherapy Vs Venetoclax and Hypomethylating Agent for Initial Therapy in Adult Acute Myeloid Leukemia

Andrew Matthews, Alexander E. Perl, Selina M. Luger, Saar Gill, Catherine Lai, David L. Porter, Sarah Skuli, Ximena Jordan Bruno, Craig W. Freyer, Alison Carulli, Martin P. Carroll, Daria V. Babushok, Noelle V. Frey, Elizabeth O. Hexner, Mary Ellen Martin, Shannon R. McCurdy, Edward A. Stadtmauer, Alison W. Loren, Vikram R Paralkar, Ivan Maillard, Keith W. Pratz
Journal: Blood
Blood (2022) 140 (Supplement 1): 1022–1024.
https://doi.org/10.1182/blood-2022-168036
Published: 2022
Journal Articles

Targeting the Mevalonate Pathway in the Mitochondria-Dependent Chemotherapy Resistance of TP53 Mutant Acute Myeloid Leukemia

Sarah Skuli, A'Ishah Bakayoko, Bryan Manning, Gerald Wertheim, Jimmy Xu, Eva Nee, Lorelai Mesaros, Ryan Hausler, Manuela Lavorato, Eiko Ogiso, Marni Falk, Kara N. Maxwell, Nicolas Skuli, Clementina Mesaros, Martin P. Carroll
Journal: Blood
Blood (2022) 140 (Supplement 1): 8791–8792.
https://doi.org/10.1182/blood-2022-165660
Published: 2022