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Journal Articles

Effect of Using Multiagent Versus Single Agent Chemotherapy on Overall Survival (OS) of Older Adults with Acute Myeloid Leukemia (AML)

Vijaya R. Bhatt, MD, Valerie K Shostrom, Sarah A. Holstein, MD PhD, Zaid S. Al-Kadhimi, MD, Lori J. Maness, MD, Ann Berger, PhD APRN-CNS, AOCNS, FAAN, James O. Armitage, MD, Krishna Gundabolu, MBBS

Blood (2019) 134 (Supplement_1): 2155.

https://doi.org/10.1182/blood-2019-122679

Published: 2019

Journal Articles

The Effect of Age and CD34+ Stem Cell Dose on Autologous Hematopoietic Stem Cell Transplantation Outcomes in Multiple Myeloma - Single Institution Experience

Madeline Skousen, Sarah A. Holstein, MD PhD, Matthew A. Lunning, DO, FACP, Elizabeth R. Lyden, MS, Gilmore Sheree, BA, Kimberly Schmit-Pokorny, Nurse Manager, James O. Armitage, MD, Zaid S. Al-Kadhimi, MD, Julie M Vose, MDMBA, Muhamed Baljevic, MD

Blood (2019) 134 (Supplement_1): 2028.

https://doi.org/10.1182/blood-2019-131594

Published: 2019

Journal Articles

In Vitro and in Vivo Activity of Melflufen in Amyloidosis

Ken Flanagan, PhD, Muntasir M Majumder, MSc, BPharm, Romika Kumari, PhD, Juho Miettinen, PhD, Ana Slipicevic, PhD, Sarah A. Holstein, MD PhD, Michelle L. Varney, MS, Minna Suvela, MSC, Fredrik Lehmann, PhD, Nina N. Nupponen, PhD, Caroline A Heckman, PhD

Blood (2019) 134 (Supplement_1): 3100.

https://doi.org/10.1182/blood-2019-125952

Published: 2019

Journal Articles

Integrating Geriatric Assessment and Genetic Profiling to Personalize Therapy Selection in Older Adults with Acute Myeloid Leukemia (AML)

Vijaya R. Bhatt, MD, Christopher Wichman, PhD, Zaid S. Al-Kadhimi, MD, Thuy T. Koll, MD, Ann Berger, PhD APRN-CNS, AOCNS, FAAN, James O. Armitage, MD, Sarah A. Holstein, MD PhD, Krishna Gundabolu, MBBS, Lori J. Maness, MD

Blood (2019) 134 (Supplement_1): 120.

https://doi.org/10.1182/blood-2019-124375

Published: 2019

Journal Articles

Geranylgeranyl Diphosphate Synthase Inhibitor and Proteasome Inhibitor Combination Therapy in Multiple Myeloma

Staci L. Haney, PhD, Michelle L. Varney, MS, Lynette M. Smith, PhD, Sarah A. Holstein, MD PhD

Blood (2019) 134 (Supplement_1): 4417.

https://doi.org/10.1182/blood-2019-129244

Published: 2019

Journal Articles

Results of a Phase I Study of Pnk-007, Allogeneic, Off the Shelf NK Cell, Post Autologous Transplant in Multiple Myeloma (NCT02955550)

Sarah A. Holstein, MD PhD, Sarah Cooley, MD, Parameswaran Hari, MBBS, MD, Sundar Jagannath, MD, Catherine R Balint, BSc, William Van Der Touw, Michele L. Donato, MD, Philip L. McCarthy, MD, Paul K. Wallace, MS, PhD, Xiaokui Zhang, PhD, Robert Hariri, MD PhD, Mohamad A. Hussein, MDMBBS, Ravi Vij, MBBS

Blood (2019) 134 (Supplement_1): 4451.

https://doi.org/10.1182/blood-2019-128467

Published: 2019

Journal Articles

Isoprenoid Amide Bisphosphonates As a Novel Class of Geranylgeranyl Diphosphate Synthase Inhibitors

Michelle L. Varney, MS, Daniel B. Goetz, BA, David F. Wiemer, PhD, Sarah A. Holstein, MD PhD

Blood (2018) 132 (Supplement 1): 4679.

https://doi.org/10.1182/blood-2018-99-112965

Published: 2018

Journal Articles

Survival Analysis from the CALGB Study of Lenalidomide Maintenance Therapy in Newly Diagnosed Multiple Myeloma Post-Autologous Stem Cell Transplantation Adjusted for Crossover (Alliance 100104)

Philip L. McCarthy, MD, Paul Richardson, Vera Suman, Miranda Cooper, Owain Saunders, Sujith Dhanasiri, Sergio Giralt, MD, Kenneth Anderson, MD, Edward Stadtmauer, Sarah A. Holstein, MD PhD

Blood (2018) 132 (Supplement 1): 4737.

https://doi.org/10.1182/blood-2018-99-113001

Published: 2018

Journal Articles

Allogeneic Stem Cell Transplantation for Multiple Myeloma: A 34-Year Experience

Courtney Venegas, BA, Matthew A. Lunning, DO, Zaid S. Al-Kadhimi, MD, Vijaya R. Bhatt, MD, Elizabeth R. Lyden, MS, Kimberly Schmit-Pokorny, Nurse Manager, James O. Armitage, MD, Julie M. Vose, MD MBA, Sarah A. Holstein, MD PhD, Muhamed Baljevic, MD

Blood (2018) 132 (Supplement 1): 5780.

https://doi.org/10.1182/blood-2018-99-116990

Published: 2018

Journal Articles

In Vivo Evaluation of Novel Geranylgeranyl Diphosphate Synthase Inhibitors

Staci L. Haney, PhD, Yashpal S. Chhonker, PhD, Michelle L. Varney, MS, Geoffrey A. Talmon, MD, Daryl J. Murry, PharmD, Sarah A. Holstein, MD PhD

Blood (2018) 132 (Supplement 1): 215.

https://doi.org/10.1182/blood-2018-99-113007

Published: 2018

Journal Articles

Preclinical Investigation of a Potent Geranylgeranyl Diphosphate Synthase Inhibitor

Staci L. Haney, PhD, Yashpal S. Chhonker, PhD, Michelle L. Varney, MS, Geoffrey A. Talmon, MD, Daryl J. Murry, PharmD, Sarah A. Holstein, MD PhD

Blood (2017) 130 (Supplement 1): 4625.

https://doi.org/10.1182/blood.V130.Suppl_1.4625.4625

Published: 2017

Journal Articles

The Association between CD34+ Dose, Platelet Recovery and Incidence of Relapse after Autologous Stem Cell Transplant in Multiple Myeloma

Muhamed Baljevic, MD, Sarah A. Holstein, MD PhD, Matthew A. Lunning, DO, Elizabeth R. Lyden, MS, James O. Armitage, MD, Julie M. Vose, MDMBA

Blood (2017) 130 (Supplement 1): 3287.

https://doi.org/10.1182/blood.V130.Suppl_1.3287.3287

Published: 2017

Journal Articles

Structure-Function Relationships of Novel Benzimidazole-Based Inhibitors of the Isoprenoid Biosynthetic Pathway in Myeloma Cells

Michelle L. Varney, MS, Nazmul H. Bhuiyan, B.S., David F. Wiemer, PhD, Sarah A. Holstein, MD PhD

Blood (2017) 130 (Supplement 1): 3345.

https://doi.org/10.1182/blood.V130.Suppl_1.3345.3345

Published: 2017

Journal Articles

Identification of Immune Phenotypes Associated with Improved Progression Free and Overall Survival for Patients with Multiple Myeloma Treated with Autologous Hematopoietic Cell Transplantation

Christine M. Ho, MD, Theresa Hahn, PhD, Paul K. Wallace, MS, PhD, Yali Zhang, Ahmad Fora, MD, George L. Chen, MD, Sarah A. Holstein, MD PhD, Patrick Mellors, Benjamin McCarthy, Sophia R. Balderman, MD, Philip L. McCarthy, MD

Blood (2016) 128 (22): 3454.

https://doi.org/10.1182/blood.V128.22.3454.3454

Published: 2016

Journal Articles

Effects of Isoprenoid Biosynthetic Pathway Inhibition on Glucose Uptake in Myeloma Cells

Kaitlyn M. Dykstra, PhD, Sarah A. Holstein, MD PhD

Blood (2016) 128 (22): 3300.

https://doi.org/10.1182/blood.V128.22.3300.3300

Published: 2016

Journal Articles

Evolution of Multiparametric Flow Cytometry Testing for Minimal Residual Disease Assessment in Multiple Myeloma and Its Impact on Clinical Outcomes: A Single Institution Experience

Nischala Ammannagari, Paul K. Wallace, MS, PhD, Theresa Hahn, PhD, Yali Zhang, Christine M. Ho, MD, Philip L. McCarthy, MD, Sarah A. Holstein, MD PhD

Blood (2016) 128 (22): 2274.

https://doi.org/10.1182/blood.V128.22.2274.2274

Published: 2016

Journal Articles

Synergistic Inhibition of Geranylgeranyl Diphosphate Synthase By a Mixture of Olefin Stereoisomers

Cheryl Allen, BS, Joseph I. Metzger, BA, Veronica S. Wills, PhD, Huaxiang Tong, PhD, Sandhya Kortagere, PhD, David F. Wiemer, PhD, Sarah A. Holstein, MD PhD

Blood (2016) 128 (22): 2320.

https://doi.org/10.1182/blood.V128.22.2320.2320

Published: 2016

Journal Articles

Effects of Novel Tropolones with Selective HDAC Inhibitor Activity in Myeloma Cells

Alyssa M. Aldridge, Kaitlyn M. Dykstra, PhD, Cheryl Allen, BS, Sean H. Colligan, BS, Eric R. Falcone, MS, Andrew J. Wiemer, PhD, Dennis L. Wright, PhD, Sarah A Holstein, MD PhD

Blood (2015) 126 (23): 3247.

https://doi.org/10.1182/blood.V126.23.3247.3247

Published: 2015

Journal Articles

A Novel Class of Geranylgeranyl Diphosphate Synthase Inhibitors: Structure-Activity Relationships of Homoisoprenoid Triazoles in Myeloma Cells

Veronica S. Wills, B.S., Cheryl Allen, BS, Ella J. Born, B.A., Xiang Zhou, B.S., David F. Wiemer, PhD, Sarah A Holstein, MD PhD

Blood (2014) 124 (21): 2156.

https://doi.org/10.1182/blood.V124.21.2156.2156

Published: 2014

Journal Articles

Synthesis and Structure-Function Relationship Of Novel Triazole Phosphonates As Inhibitors Of Rab Geranylgeranyl Transferase

Sarah D. Ferree, Xiang Zhou, B.S., Veronica S. Wills, B.S., Ella J. Born, B.A., Huaxiang Tong, PhD, David F. Wiemer, PhD, Sarah A Holstein, MD, PhD

Blood (2013) 122 (21): 4223.

https://doi.org/10.1182/blood.V122.21.4223.4223

Published: 2013

NARROW

Effect of Using Multiagent Versus Single Agent Chemotherapy on Overall Survival (OS) of Older Adults with Acute Myeloid Leukemia (AML)

The Effect of Age and CD34+ Stem Cell Dose on Autologous Hematopoietic Stem Cell Transplantation Outcomes in Multiple Myeloma - Single Institution Experience

In Vitro and in Vivo Activity of Melflufen in Amyloidosis

Integrating Geriatric Assessment and Genetic Profiling to Personalize Therapy Selection in Older Adults with Acute Myeloid Leukemia (AML)

Geranylgeranyl Diphosphate Synthase Inhibitor and Proteasome Inhibitor Combination Therapy in Multiple Myeloma

Results of a Phase I Study of Pnk-007, Allogeneic, Off the Shelf NK Cell, Post Autologous Transplant in Multiple Myeloma (NCT02955550)

Isoprenoid Amide Bisphosphonates As a Novel Class of Geranylgeranyl Diphosphate Synthase Inhibitors

Survival Analysis from the CALGB Study of Lenalidomide Maintenance Therapy in Newly Diagnosed Multiple Myeloma Post-Autologous Stem Cell Transplantation Adjusted for Crossover (Alliance 100104)

Allogeneic Stem Cell Transplantation for Multiple Myeloma: A 34-Year Experience

In Vivo Evaluation of Novel Geranylgeranyl Diphosphate Synthase Inhibitors

Preclinical Investigation of a Potent Geranylgeranyl Diphosphate Synthase Inhibitor

The Association between CD34+ Dose, Platelet Recovery and Incidence of Relapse after Autologous Stem Cell Transplant in Multiple Myeloma

Structure-Function Relationships of Novel Benzimidazole-Based Inhibitors of the Isoprenoid Biosynthetic Pathway in Myeloma Cells

Identification of Immune Phenotypes Associated with Improved Progression Free and Overall Survival for Patients with Multiple Myeloma Treated with Autologous Hematopoietic Cell Transplantation

Effects of Isoprenoid Biosynthetic Pathway Inhibition on Glucose Uptake in Myeloma Cells

Evolution of Multiparametric Flow Cytometry Testing for Minimal Residual Disease Assessment in Multiple Myeloma and Its Impact on Clinical Outcomes: A Single Institution Experience

Synergistic Inhibition of Geranylgeranyl Diphosphate Synthase By a Mixture of Olefin Stereoisomers

Effects of Novel Tropolones with Selective HDAC Inhibitor Activity in Myeloma Cells

A Novel Class of Geranylgeranyl Diphosphate Synthase Inhibitors: Structure-Activity Relationships of Homoisoprenoid Triazoles in Myeloma Cells

Synthesis and Structure-Function Relationship Of Novel Triazole Phosphonates As Inhibitors Of Rab Geranylgeranyl Transferase

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American Society of Hematology

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American Society of Hematology

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