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Journal Articles

Redesign of EAF Peg Hb As an Oxygen Transfer Catalyst for Improved Tissue Oxygenation of Hypoxic Areas: A Therapeutic for Anemia and Sickle Cell Disease

Savita Bhutoria, PhD, Amy Tsai, PhD, Marcos Intaglietta, PhD, Sandra M. Suzuka, MS, Sangeetha Thangaswamy, PhD, Prabhakaran Muthuchidambaram, PhD, Caterina Minniti, MD, Henny Heisler H Billett, MD, Craig A Branch, PhD, Seetharama A Acharya, PhD

Blood (2016) 128 (22): 4845.

https://doi.org/10.1182/blood.V128.22.4845.4845

Published: 2016

Journal Articles

Therapeutic Amelioration of Vaso-Occlusion and Blood Flow Impairment in Transgenic Sickle Mice By the Antioxidant Flavonoid Quercetin

Sangeetha Thangaswamy, PhD, Henny H Billett, MD, Craig A. Branch, PhD, Sandra M. Suzuka, M.S., Seetharama A Acharya, PhD

Blood (2014) 124 (21): 4054.

https://doi.org/10.1182/blood.V124.21.4054.4054

Published: 2014

Journal Articles

Protective Effect of Fetal Hemoglobin On Inflammation-Induced Expression of Hypoxia-Inducible Factor-1α (HIF-1α) in Sickle Mice: Microvascular Implications

Dhananjay K. Kaul, Ph.D., Mary E. Fabry, Ph.D., Sandra M Suzuka, M.S., Janki Shah, M.S.

Blood (2012) 120 (21): 3250.

https://doi.org/10.1182/blood.V120.21.3250.3250

Published: 2012

Journal Articles

The Supra Perfusion Agent PEGylated Albumin and Its Tempol Derivative Improve Blood Oxygenation and Ameliorate Inflammatory Response in Sickle Transgenic Mice

Mary E. Fabry, PhD, Seetharama A. Acharya, PhD, Fantao Meng, PhD, Sandra M. Suzuka, M.S., Dhananjay K. Kaul, Ph.D.

Blood (2011) 118 (21): 2117.

https://doi.org/10.1182/blood.V118.21.2117.2117

Published: 2011

Journal Articles

Anti-Interleukin-1β Antibody-Based Therapy Ameliorates Endothelial Activation and Inflammation in Sickle Mice

Dhananjay K. Kaul, Ph.D., Sangeetha Thangaswamy, Ph.D., Sandra M. Suzuka, M.S., Mary E. Fabry, Ph.D., Alan A. Wanderer, M.D., Hermann Gram, Ph.D.

Blood (2011) 118 (21): 848.

https://doi.org/10.1182/blood.V118.21.848.848

Published: 2011

Journal Articles

Endothelial Activation by Sickle Mouse Red Cells and Their Endothelial Adhesion In Vivo is Abolished by Catalase Treatment of Sickle Cells, but Not Quiescent Endothelium, Implying a Role of Heme-Mediated Peroxide Generation in Sickle Cell Adhesion.

Dhananjay K. Kaul, PhD, Sandra M. Suzuka, MS, Mary Fabry, PhD

Blood (2009) 114 (22): 902.

https://doi.org/10.1182/blood.V114.22.902.902

Published: 2009

Journal Articles

huGTPCH Expressing S+S-Antilles Mice Have Reduced Gardos Channel Activity, Endothelin-1 Expression, and Endothelin Receptor A and B Expression, While Total Biopterin and Percent Tetrahydrobiopterin Are Increased

José R. Romero, PhD, Adriana Muniz, PhD, Ashley Hale, BSc, Nicholas J. Alp, PhD, DM, MRCP, Alicia Rivera, PhD, Sandra M. Suzuka, MS, Keith M. Channon, MD, FRCP, Mary E. Fabry, PhD

Blood (2008) 112 (11): 537.

https://doi.org/10.1182/blood.V112.11.537.537

Published: 2008

Journal Articles

A Transgenic Mouse Model for Adult Acute Chest Syndrome.

Mary E. Fabry, PhD, Naseem Ahmed, PhD, Sandra M. Suzuka, MS, Ronald L. Nagel, MD, Rani Sellers, PhD, Elizabeth Klings, MD

Blood (2007) 110 (11): 2259.

https://doi.org/10.1182/blood.V110.11.2259.2259

Published: 2007

Journal Articles

Apotransferrin Injection Leads to More Effective Erythropoiesis in β-Thalassemic Mice.

Yelena Z. Ginzburg, MD, Anne C. Rybicki, PhD, Sandra M. Suzuka, MS, Leni von Bonsdorff, DSc, Mary E. Fabry, PhD, Ronald L. Nagel, MD

Blood (2007) 110 (11): 276.

https://doi.org/10.1182/blood.V110.11.276.276

Published: 2007

Journal Articles

Determinants of Sickle Cell Density Distribution: A Study of Benin Twins.

Mary E. Fabry, PhD, Anne C. Rybicki, PhD, Sandra M. Suzuka, MS, M. Cherif Rahimy, MD, Rajagopal Krishnamoorthy, PhD, Ronald L. Nagel, MD

Blood (2006) 108 (11): 1244.

https://doi.org/10.1182/blood.V108.11.1244.1244

Published: 2006

Journal Articles

What’s Good for the Marrow Is Bad for the Heart: Improving Anemia in a Cardiac Iron Overload Model of Hbb th1/th1 Mice.

Yelena Z. Ginzburg, MD, Sandra M. Suzuka, MS, Mary E. Fabry, PhD, Ronald L. Nagel, MD

Blood (2006) 108 (11): 1767.

https://doi.org/10.1182/blood.V108.11.1767.1767

Published: 2006

Journal Articles

Positively Charged Alpha-Chains Can Stimulate K-Cl Cotransport in Transgenic Mouse Red Cells.

Jose R. Romero, PhD, Sandra M. Suzuka, MS, Raouf Alami, PhD, Steven N. Feiring, PhD, Eric E. Bouhassira, PhD, Ronald L. Nagel, MD, Mary E. Fabry, PhD

Blood (2005) 106 (11): 2326.

https://doi.org/10.1182/blood.V106.11.2326.2326

Published: 2005

Journal Articles

K-Cl Cotransport and MCHC in HbE Transgenic Mice and Human HbE.

Jose R. Romero, PhD, Alicia Rivera, PhD, Zipora Etzion, PhD, Sandra M. Suzuka, MS, Elliott Vichinsky, MD, Ronald L. Nagel, MD, Mary E. Fabry, PhD

Blood (2005) 106 (11): 3810.

https://doi.org/10.1182/blood.V106.11.3810.3810

Published: 2005

Journal Articles

A Transgenic Mouse Model of Homozygous HbE Disease.

Qiuying Chen, PhD, Frans A. Kuypers, PhD, Anne C. Rybicki, PhD, Amrita Bhagat, BS, Sandra M. Suzuka, MS, Mary E. Fabry, PhD, Ronald L. Nagel, MD, Rhoda Elison Hirsch, PhD

Blood (2005) 106 (11): 3192.

https://doi.org/10.1182/blood.V106.11.3192.3192

Published: 2005

Journal Articles

Arginine Supplementation of Sickle Transgenic Mice Leads to a Rapid Decrease in MCHC and Percent Dense Cells and a Slow Increase When Supplementation Is Discontinued.

Mary E. Fabry, PhD, Zipora Etzion, PhD, Robert M. Bookchin, MD, Sandra M. Suzuka, MS, Ronald L. Nagel, MD

Blood (2004) 104 (11): 3579.

https://doi.org/10.1182/blood.V104.11.3579.3579

Published: 2004

Journal Articles

Generation of Transgenic Mice Expressing Human Hemoglobin E.

Qiuying Chen, PhD, Eric E. Bouhassira, PhD, Arnaud Besse, PhD, Sandra M. Suzuka, MS, Mary E. Fabry, PhD, Ronald L. Nagel, MD, Rhoda Elison-Hirsch, PhD

Blood (2004) 104 (11): 3583.

https://doi.org/10.1182/blood.V104.11.3583.3583

Published: 2004

Journal Articles

Detection of Acute Chest Syndrome by MRI in a Sickle Transgenic Mouse Model.

Richard P. Kennan, PhD, Dawn Alleyne, MD, Thomas K. Aldrich, MD, Sandra M. Suzuka, MS, Robert Renick, BS, Ronald L. Nagel, MD, Mary E. Fabry, PhD

Blood (2004) 104 (11): 3749.

https://doi.org/10.1182/blood.V104.11.3749.3749

Published: 2004

Journal Articles

Expression of HbC and HbS, but not HbA, results in activation of K-Cl cotransport activity in transgenic mouse red cells

Jose R. Romero, Sandra M. Suzuka, Ronald L. Nagel, Mary E. Fabry

Blood (2004) 103 (6): 2384–2390.

https://doi.org/10.1182/blood-2003-01-0237

Published: 2004

Journal Articles

Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity

José R. Romero, Sandra M. Suzuka, Ronald L. Nagel, Mary E. Fabry

Blood (2002) 99 (4): 1103–1108.

https://doi.org/10.1182/blood.V99.4.1103

Published: 2002

Journal Articles

Direct intracellular measurement of deoxygenated hemoglobin S solubility

Mary E. Fabry, Laurephile Desrosiers, Sandra M. Suzuka

Blood (2001) 98 (3): 883–884.

https://doi.org/10.1182/blood.V98.3.883

Published: 2001

NARROW

Redesign of EAF Peg Hb As an Oxygen Transfer Catalyst for Improved Tissue Oxygenation of Hypoxic Areas: A Therapeutic for Anemia and Sickle Cell Disease

Therapeutic Amelioration of Vaso-Occlusion and Blood Flow Impairment in Transgenic Sickle Mice By the Antioxidant Flavonoid Quercetin

Protective Effect of Fetal Hemoglobin On Inflammation-Induced Expression of Hypoxia-Inducible Factor-1α (HIF-1α) in Sickle Mice: Microvascular Implications

The Supra Perfusion Agent PEGylated Albumin and Its Tempol Derivative Improve Blood Oxygenation and Ameliorate Inflammatory Response in Sickle Transgenic Mice

Anti-Interleukin-1β Antibody-Based Therapy Ameliorates Endothelial Activation and Inflammation in Sickle Mice

Endothelial Activation by Sickle Mouse Red Cells and Their Endothelial Adhesion In Vivo is Abolished by Catalase Treatment of Sickle Cells, but Not Quiescent Endothelium, Implying a Role of Heme-Mediated Peroxide Generation in Sickle Cell Adhesion.

huGTPCH Expressing S+S-Antilles Mice Have Reduced Gardos Channel Activity, Endothelin-1 Expression, and Endothelin Receptor A and B Expression, While Total Biopterin and Percent Tetrahydrobiopterin Are Increased

A Transgenic Mouse Model for Adult Acute Chest Syndrome.

Apotransferrin Injection Leads to More Effective Erythropoiesis in β-Thalassemic Mice.

Determinants of Sickle Cell Density Distribution: A Study of Benin Twins.

What’s Good for the Marrow Is Bad for the Heart: Improving Anemia in a Cardiac Iron Overload Model of Hbb th1/th1 Mice.

Positively Charged Alpha-Chains Can Stimulate K-Cl Cotransport in Transgenic Mouse Red Cells.

K-Cl Cotransport and MCHC in HbE Transgenic Mice and Human HbE.

A Transgenic Mouse Model of Homozygous HbE Disease.

Arginine Supplementation of Sickle Transgenic Mice Leads to a Rapid Decrease in MCHC and Percent Dense Cells and a Slow Increase When Supplementation Is Discontinued.

Generation of Transgenic Mice Expressing Human Hemoglobin E.

Detection of Acute Chest Syndrome by MRI in a Sickle Transgenic Mouse Model.

Expression of HbC and HbS, but not HbA, results in activation of K-Cl cotransport activity in transgenic mouse red cells

Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity

Direct intracellular measurement of deoxygenated hemoglobin S solubility

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American Society of Hematology

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