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Journal Articles

DNMT3A and NPM1 Double Mutated AML Is a Phenomenon of the Younger Patient and Could Represent a New Entity

Luca Vincenzo Cappelli, MD, Manja Meggendorfer, PhD, Frank Dicker, PhD, Sabine Jeromin, PhD, Stephan Hutter, PhD, Wolfgang Kern, MD, Torsten Haferlach, MD, Claudia Haferlach, MD, Alexander Höllein, MD

Blood (2018) 132 (Supplement 1): 2803.

https://doi.org/10.1182/blood-2018-99-113452

Published: 2018

Journal Articles

Final Evaluation of Randomized CML-Study IV: 10-Year Survival and Evolution of Terminal Phase

Rüdiger Hehlmann, MD, Michael Lauseker, PhD, Susanne Saussele, MD, Markus Pfirrmann, Stefan W. Krause, MD, Hans-Jochem Kolb, MD, Andreas Neubauer, MD, Dieter K. Hossfeld, Christoph Nerl, MD, Alois Gratwohl, MD, Gabriela M. Baerlocher, Dominik Heim, MD, Tim Henrik Bruemmendorf, Alice Fabarius, PhD, Claudia Haferlach, MD, Brigitte Schlegelberger, MD PhD, Martin C. Müller, MD, Sabine Jeromin, PhD, Ulrike Proetel, PhD, Katharina Kohlbrenner, PhD, Astghik Voskanyan, PhD, Sébastien Rinaldetti, Wolfgang Seifarth, PhD, Birgit Spiess, Leopold Balleisen, MD, Maria E Goebeler, MD, Mathias Hänel, MD, Anthony D. Ho, MD, J Dengler, C Falge, Lothar Kanz, MD, Claus-Henning Köhne, MD, PhD, Andreas Burchert, MD, Michael Kneba, MD PhD, Frank Stegelmann, MD, C Köhne, Hans-Walter Lindemann, C Waller, Michael Pfreundschuh, MD, Karsten Spiekermann, Wolfgang E Berdel, MD, L Müller, Matthias Edinger, MD, Jiri Mayer, Prof, MD SCs, Dietrich W Beelen, MD PhD, Martin Bentz, MD, Hartmut Link, MDPhD, Bernd Hertenstein, MD, R Fuchs, Martin Wernli, MD, F Schlegel, Rudolph Schlag, M de Wit, Lorenz Trümper, MD, H Hebarth, M Hahn, Jörg Thomalla, MD, Christof Scheid, MD, Philippe Schafhausen, MD, Walter Verbeek, MD, Michael J. Eckart, MD, Winfried Gassmann, MD PhD, Antonio Pezzutto, MD, Michael Schenk, Peter Brossart, MD, Thomas Geer, MD, Stephan Bildat, E Schäfer, Andreas Hochhaus, MD, Joerg Hasford

Blood (2017) 130 (Supplement 1): 897.

https://doi.org/10.1182/blood.V130.Suppl_1.897.897

Published: 2017

Journal Articles

Impact of Infrequently Mutated Genes on Prognosis in 531 Untreated CLL Patients

Sabine Jeromin, PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Torsten Haferlach, MD, Wolfgang Kern, MD

Blood (2017) 130 (Supplement 1): 3005.

https://doi.org/10.1182/blood.V130.Suppl_1.3005.3005

Published: 2017

Journal Articles

In Depth Molecular Characterization of AML with RUNX1-RUNX1T1 at Diagnosis and Relapse

Alexander Höllein, MD, Niroshan Nadarajah, Manja Meggendorfer, PhD, Annette Fasan, PhD, Sabine Jeromin, PhD, Wolfgang Kern, MD, Claudia Haferlach, MD, Torsten Haferlach, MD

Blood (2017) 130 (Supplement 1): 1416.

https://doi.org/10.1182/blood.V130.Suppl_1.1416.1416

Published: 2017

Journal Articles

NPM1 Mutated AML Can Relapse with Wildtype NPM1 and Evolve with Novel Mutations: Implications for Pathobiology and MRD Monitoring

Alexander Höllein, MD, Manja Meggendorfer, PhD, Annette Fasan, PhD, Frank Dicker, PhD, Sabine Jeromin, PhD, Niroshan Nadarajah, Wolfgang Kern, MD, Claudia Haferlach, MD, Torsten Haferlach, MD

Blood (2017) 130 (Supplement 1): 1417.

https://doi.org/10.1182/blood.V130.Suppl_1.1417.1417

Published: 2017

Journal Articles

Clonal Evolution of Molecular and Cytogenetic Aberrations in 80 CLL Patients

Sabine Jeromin, PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Torsten Haferlach, MD, Wolfgang Kern, MD

Blood (2017) 130 (Supplement 1): 1720.

https://doi.org/10.1182/blood.V130.Suppl_1.1720.1720

Published: 2017

Journal Articles

Homozygosity of Mutated Calreticulin in Myeloproliferative Neoplasms By an Acquired Chromosome 19p UPD Is Associated with Deletions in the Long Arm of Chromosome 5 and SF3B1 Mutations

Anna Stengel, PhD, Manja Meggendorfer, PhD, Wolfgang Kern, MD, Torsten Haferlach, MD, Claudia Haferlach, MD, Sabine Jeromin, PhD

Blood (2016) 128 (22): 3145.

https://doi.org/10.1182/blood.V128.22.3145.3145

Published: 2016

Journal Articles

Characterization and Prognostic Impact of Multiple Productive IGHV Rearrangements in CLL

Sabine Jeromin, PhD, Claudia Haferlach, MD, Frank Dicker, PhD, Manja Meggendorfer, PhD, Torsten Haferlach, MD, Wolfgang Kern, MD

Blood (2016) 128 (22): 3207.

https://doi.org/10.1182/blood.V128.22.3207.3207

Published: 2016

Journal Articles

Cytogenetic and Molecular Genetic Clonal Evolution in CLL Is Associated with an Unmutated IGHV Status and Frequently Leads to a Combination of Loss of 17p and TP53 mutation

Claudia Haferlach, MD, Sabine Jeromin, PhD, Niroshan Nadarajah, M.Sc., Melanie Zenger, Wolfgang Kern, MD, Torsten Haferlach, MD

Blood (2016) 128 (22): 3213.

https://doi.org/10.1182/blood.V128.22.3213.3213

Published: 2016

Journal Articles

Patients with TP53 Disruption and IGHV Mutated Status Show Indolent Clinical Course: A Study on 1,327 Treatment-Naive CLL Cases

Sabine Jeromin, PhD, Claudia Haferlach, MD, Frank Dicker, PhD, Torsten Haferlach, MD, Wolfgang Kern, MD

Blood (2016) 128 (22): 4378.

https://doi.org/10.1182/blood.V128.22.4378.4378

Published: 2016

Journal Articles

In Chronic Lymphocytic Leukemia the Gain of the Short Arm of Chromosome 2 Is Highly Associated with an Unmutated IGHV status, 11q/ ATM Deletion, SF3B1 Mutation and a Complex Karyotype

Claudia Haferlach, MD, Sabine Jeromin, PhD, Anna Stengel, PhD, Manja Meggendorfer, PhD, Melanie Zenger, Wolfgang Kern, MD, Torsten Haferlach, MD

Blood (2016) 128 (22): 4379.

https://doi.org/10.1182/blood.V128.22.4379.4379

Published: 2016

Journal Articles

SF3B1 Mutations in AML, MDS and MDS/MPN-RS-T Are Accompanied By Different Other Gene Mutations: Impact for Targeted Treatment Studies

Manja Meggendorfer, PhD, Sabine Jeromin, PhD, Karolína Perglerová, Claudia Haferlach, MD, Wolfgang Kern, MD, Torsten Haferlach, MD

Blood (2016) 128 (22): 1976.

https://doi.org/10.1182/blood.V128.22.1976.1976

Published: 2016

Journal Articles

In CLL with Normal Karyotype By Conventional and Genomic Array Karyotyping the Prognostic Impact of an Unmutated IGHV Status Is Stronger Than the Impact of Gene Mutations

Calogero Vetro, MD, Torsten Haferlach, MD, Manja Meggendorfer, PhD, Sabine Jeromin, PhD, Constance Regina Baer, PhD, Niroshan Nadarajah, M.Sc., Wolfgang Kern, MD, Claudia Haferlach, MD

Blood (2016) 128 (22): 4357.

https://doi.org/10.1182/blood.V128.22.4357.4357

Published: 2016

Journal Articles

In Depth Characterization of CLL with Normal Karyotype By Array CGH and Mutation Screening

Claudia Haferlach, MD, Sabine Jeromin, PhD, Wolfgang Kern, MD, Susanne Schnittger, PhD, Torsten Haferlach

Blood (2015) 126 (23): 1707.

https://doi.org/10.1182/blood.V126.23.1707.1707

Published: 2015

Journal Articles

Modulation of the Clonal Composition in Relapsed CLL: A Study Based on Targeted Deep-Sequencing of ATM, BIRC3, NOTCH1, POT1, SF3B1, SAMHD1 and TP53

Sabine Jeromin, PhD, Wolfgang Kern, MD, Richard Schabath, Tamara Alpermann, Niroshan Nadarajah, M.Sc., Manja Meggendorfer, PhD, Susanne Schnittger, PhD, Torsten Haferlach, Claudia Haferlach, MD

Blood (2015) 126 (23): 1721.

https://doi.org/10.1182/blood.V126.23.1721.1721

Published: 2015

Journal Articles

Characterization of Del(14)(q24q32) in Mature B-Cell Neoplasms By Array-CGH, Cytogenetics and Molecular Mutations

Sabine Jeromin, PhD, Wolfgang Kern, MD, Torsten Haferlach, Susanne Schnittger, PhD, Claudia Haferlach, MD

Blood (2015) 126 (23): 3901.

https://doi.org/10.1182/blood.V126.23.3901.3901

Published: 2015

Journal Articles

Higher Percentages of Ring Sideroblasts and SF3B1 Mutations in Patients with AML Correlate with Mutations in TP53 and Adverse Cytogenetics, but Have No Independent Impact on Outcome

Pedro Martin-Cabrera, MD, Sabine Jeromin, PhD, Tamara Alpermann, Karolína Perglerová, Claudia Haferlach, MD, Wolfgang Kern, MD, Torsten Haferlach

Blood (2015) 126 (23): 3847.

https://doi.org/10.1182/blood.V126.23.3847.3847

Published: 2015

Journal Articles

Mutations in CALR Are Associated with Del(13q) and Are Mutually Exclusive of Monosomy 7 in BCR-ABL1 -Negative MPN

Sabine Jeromin, PhD, Claudia Haferlach, MD, Manja Meggendorfer, PhD, Wolfgang Kern, MD, Torsten Haferlach, MD, Susanne Schnittger, PhD

Blood (2014) 124 (21): 1870.

https://doi.org/10.1182/blood.V124.21.1870.1870

Published: 2014

Journal Articles

Molecular Analyses of MDS/MPN Overlap Entities According to WHO Classification Reveal a Distinct Molecular Pattern for MDS/MPN, Unclassifiable

Manja Meggendorfer, PhD, Torsten Haferlach, MD, Sabine Jeromin, PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Susanne Schnittger, PhD

Blood (2014) 124 (21): 4618.

https://doi.org/10.1182/blood.V124.21.4618.4618

Published: 2014

Journal Articles

Characterization and Quantification Of Rare BCR-ABL1 Fusion Transcripts

Susanne Schnittger, PhD, Frank Dicker, PhD, Tamara Alpermann, Christiane Eder, PhD, Annette Fasan, PhD, Simone Weber, Sabine Jeromin, PhD, Manja Meggendorfer, PhD, Wolfgang Kern, MD, Torsten Haferlach, MD, Claudia Haferlach, MD

Blood (2013) 122 (21): 4013.

https://doi.org/10.1182/blood.V122.21.4013.4013

Published: 2013

NARROW

DNMT3A and NPM1 Double Mutated AML Is a Phenomenon of the Younger Patient and Could Represent a New Entity

Final Evaluation of Randomized CML-Study IV: 10-Year Survival and Evolution of Terminal Phase

Impact of Infrequently Mutated Genes on Prognosis in 531 Untreated CLL Patients

In Depth Molecular Characterization of AML with RUNX1-RUNX1T1 at Diagnosis and Relapse

NPM1 Mutated AML Can Relapse with Wildtype NPM1 and Evolve with Novel Mutations: Implications for Pathobiology and MRD Monitoring

Clonal Evolution of Molecular and Cytogenetic Aberrations in 80 CLL Patients

Homozygosity of Mutated Calreticulin in Myeloproliferative Neoplasms By an Acquired Chromosome 19p UPD Is Associated with Deletions in the Long Arm of Chromosome 5 and SF3B1 Mutations

Characterization and Prognostic Impact of Multiple Productive IGHV Rearrangements in CLL

Cytogenetic and Molecular Genetic Clonal Evolution in CLL Is Associated with an Unmutated IGHV Status and Frequently Leads to a Combination of Loss of 17p and TP53 mutation

Patients with TP53 Disruption and IGHV Mutated Status Show Indolent Clinical Course: A Study on 1,327 Treatment-Naive CLL Cases

In Chronic Lymphocytic Leukemia the Gain of the Short Arm of Chromosome 2 Is Highly Associated with an Unmutated IGHV status, 11q/ ATM Deletion, SF3B1 Mutation and a Complex Karyotype

SF3B1 Mutations in AML, MDS and MDS/MPN-RS-T Are Accompanied By Different Other Gene Mutations: Impact for Targeted Treatment Studies

In CLL with Normal Karyotype By Conventional and Genomic Array Karyotyping the Prognostic Impact of an Unmutated IGHV Status Is Stronger Than the Impact of Gene Mutations

In Depth Characterization of CLL with Normal Karyotype By Array CGH and Mutation Screening

Modulation of the Clonal Composition in Relapsed CLL: A Study Based on Targeted Deep-Sequencing of ATM, BIRC3, NOTCH1, POT1, SF3B1, SAMHD1 and TP53

Characterization of Del(14)(q24q32) in Mature B-Cell Neoplasms By Array-CGH, Cytogenetics and Molecular Mutations

Higher Percentages of Ring Sideroblasts and SF3B1 Mutations in Patients with AML Correlate with Mutations in TP53 and Adverse Cytogenetics, but Have No Independent Impact on Outcome

Mutations in CALR Are Associated with Del(13q) and Are Mutually Exclusive of Monosomy 7 in BCR-ABL1 -Negative MPN

Molecular Analyses of MDS/MPN Overlap Entities According to WHO Classification Reveal a Distinct Molecular Pattern for MDS/MPN, Unclassifiable

Characterization and Quantification Of Rare BCR-ABL1 Fusion Transcripts

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American Society of Hematology

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