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Robert G. Schaub, PhD
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Journal Articles

Inhibition of Von Willebrand Factor (VWF) by ARC1779 Normalizes Von Willebrand Factor/FVIII Levels and Corrects Thrombocytopenia in VWD Type 2b Patients,

Petra Jilma-Stohlawetz, MD, Paul Knoebl, MD, Ingrid Pabinger, MD, James Gilbert, MD, Robert G. Schaub, PhD, Bernd Jilma, MD
Journal: Blood
Blood (2011) 118 (21): 3377.
https://doi.org/10.1182/blood.V118.21.3377.3377
Published: 2011
Journal Articles

Investigation Into the Mechanism of Action and Binding Site of BAX 499, An Aptamer Against Tissue Factor Pathway Inhibitor

Emily K. Waters, PhD, Ryan M. Genga, Heather A. Thomson, Robert G. Schaub, PhD, Jeffrey C. Kurz, PhD, Kathleen E. McGinness, PhD
Journal: Blood
Blood (2011) 118 (21): 1214.
https://doi.org/10.1182/blood.V118.21.1214.1214
Published: 2011
Journal Articles

TFPI Antagonist Aptamer ARC19499 Is a Procoagulant In Vitro and In Vivo.

Kathleen E. McGinness, PhD, Emily K. Waters, PhD, Ryan M. Genga, Karen A. Olson, PhD, Jennifer A. Nelson, PhD, Jeffrey C. Kurz, PhD, Robert G. Schaub, PhD
Journal: Blood
Blood (2010) 116 (21): 1134.
https://doi.org/10.1182/blood.V116.21.1134.1134
Published: 2010
Journal Articles

Single-Stranded Oligonucleotide Binding to P-Selectin Inhibits Adhesion of Sickle Red Blood Cells and Leukocytes to Endothelial Cells in Sickle Cell Model Mice: Novel Therapeutics for Vaso-Occlusive Episodes.

Diana Gutsaeva, PhD, James Parkerson, Robert G Schaub, PhD, Jeffrey Kurz, Alvin Head, MD
Journal: Blood
Blood (2009) 114 (22): 1545.
https://doi.org/10.1182/blood.V114.22.1545.1545
Published: 2009
Journal Articles

Evaluation of a Novel Anti-P-Selectin Aptamer ARC5690 On Venous Inflammation Following Acute Venous Thrombosis.

Jose Antonio Diaz, MD, Patrick A Lester, DVM, Jeffrey C Kurz, PhD, Shirley K Wrobleski, BS, LVT, Angela E Hawley, BS, Robert E Sigler, DVM, PhD, Thomas W Wakefield, MD, Robert G Schaub, PhD, Daniel Myers, DVM, MPH, DACLAM
Journal: Blood
Blood (2009) 114 (22): 3599.
https://doi.org/10.1182/blood.V114.22.3599.3599
Published: 2009
Journal Articles

An Aptamer Antagonist of Tissue Factor Pathway Inhibitor Improves Coagulation in Hemophilia A and FVIII Antibody-Treated Plasma.

Emily K. Waters, PhD, Jeffrey C. Kurz, PhD, Ryan Genga, Jennifer A Nelson, PhD, Kathleen E. McGinness, PhD, Robert G. Schaub, PhD
Journal: Blood
Blood (2009) 114 (22): 544.
https://doi.org/10.1182/blood.V114.22.544.544
Published: 2009
Journal Articles

The Anti Von Willebrand Factor Aptamer ARC1779 Prevents the Desmopressin-Induced Thrombocytopenia in VWD Type 2B.

Petra Paulinska, MD, Bernd Jilma, MD, Christa Firbas, MD, Robert G Schaub, PhD, James C. Gilbert, MD, Paul Knoebl, MD
Journal: Blood
Blood (2008) 112 (11): 3374.
https://doi.org/10.1182/blood.V112.11.3374.3374
Published: 2008
Journal Articles

Crystal Structure of Von Willebrand Factor (VWF) A1 Domain in Complex with Aptamer ARC1172, An Inhibitor of VWF-Platelet Binding

Ren-Huai Huang, PhD, David Fremont, PhD, Elodee A Tuley, John L Diener, PhD, Robert G Schaub, PhD, J. Evan Sadler, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 257.
https://doi.org/10.1182/blood.V112.11.257.257
Published: 2008
Journal Articles

Anti Von Willebrand Factor Aptamer ARC 1779 for Refractory Thrombotic Thrombocytopenic Purpura.

Chri sta Firbas, MD, Bernd Jilma, MD, Patricia G Wagner, Renta Hutabarat, Robert G Schaub, PhD, James C. Gilbert, MD, Paul Knoebl, MD
Journal: Blood
Blood (2008) 112 (11): 2298.
https://doi.org/10.1182/blood.V112.11.2298.2298
Published: 2008