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Journal Articles

A Subcutaneously Administered RNAi Therapeutic (ALN-AT3) Targeting Antithrombin for Treatment of Hemophilia: Interim Phase 1 Study Results in Healthy Volunteers and Patients with Hemophilia a or B

Benny Sorensen, MD PhD, Tim Mant, MD, Akin Akinc, PhD, Amy Simon, MD, Lauren Melton, Christian Lynam, Andrew Strahs, PhD, Alfica Sehgal, PhD, Renta Hutabarat, PhD, Prasoon Chaturvedi, PhD, Scott Barros, PhD, Akshay Vaishnaw, MD PhD, Aln-AT Investigators
Journal: Blood
Blood (2014) 124 (21): 693.
https://doi.org/10.1182/blood.V124.21.693.693
Published: 2014
Journal Articles

Proof of Concept for the Anti Von Willebrand Factor Aptamer in Patients with Relapsing Thrombotic Thrombocytopenic Purpura (TTP).

Bernd Ji lma, MD, Petra Jilma, MD, Petra Paulinska, MD, James C. Gilbert, MD, Renta Hutabarat, PhD, Trish Wagner, Paul Knoebl, MD
Journal: Blood
Blood (2008) 112 (11): 2290.
https://doi.org/10.1182/blood.V112.11.2290.2290
Published: 2008
Journal Articles

Anti Von Willebrand Factor Aptamer ARC 1779 for Refractory Thrombotic Thrombocytopenic Purpura.

Chri sta Firbas, MD, Bernd Jilma, MD, Patricia G Wagner, Renta Hutabarat, Robert G Schaub, PhD, James C. Gilbert, MD, Paul Knoebl, MD
Journal: Blood
Blood (2008) 112 (11): 2298.
https://doi.org/10.1182/blood.V112.11.2298.2298
Published: 2008
Journal Articles

Discovery, Engineering and Pre-Clinical Evaluation of an Anti-vWF A1 Domain Aptamer.

John L. Diener, PhD, H.A. Daniel Lagasse, BS, Madaline Gilbert, MS, Patricia Merlino, MS, Jason Killough, BS, H. Nicholas Marsh, PhD, Ryan M. Boomer, BS, Joseph M. Fraone, BS, Thomas McCauley, PhD, Ankit Makim, BS, Scott D. Lewis, BS, Larry Cai, MS, Renta Hutabarat, PhD, James B. Rottman, PhD/DVM, Claude Benedict, MD/PhD, David Fontana, PhD
Journal: Blood
Blood (2006) 108 (11): 3930.
https://doi.org/10.1182/blood.V108.11.3930.3930
Published: 2006