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Robert E. Fleming, MD
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Journal Articles

Erythroferrone Regulates Bone Remodeling in β-Thalassemia

Melanie Castro-Mollo, MD, Marc Ruiz Martinez, PhD, Maria Feola, PhD, Anisa Azatovna Gumerova, MD, Carla Casu, PhD, Robert E Fleming, MD, Stefano Rivella, PhD, Tony Yuen, PhD, Mone Zaidi, MD PhD, Yelena Ginzburg, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2.
https://doi.org/10.1182/blood-2019-125822
Published: 2019
Journal Articles

Iron Restriction Improves Markers of Disease Severity in the Townes Mouse Model of Sickle Cell Anemia

Nermi Parrow, PhD, Pierre-Christian Violet, PhD, Nisha George, PhD, Faris Ali, Shivam Bhanvadia, Mark Levine, MD, Robert E Fleming, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2261.
https://doi.org/10.1182/blood-2019-130732
Published: 2019
Journal Articles

Iron Binding to Specific Lobes of Transferrin Differentially Affects Erythropoiesis and Hepcidin Signaling

Nermi Parrow, PhD, Amaliris Gonzalez, PhD, Yihang Li, PhD, Princy Prasad, Luke Mammen, Faris Ali, Edvinas Vaicikauskas, Maria Feola, PhD, Yelena Ginzburg, MD, Stefano Rivella, PhD, Robert E Fleming, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 173.
https://doi.org/10.1182/blood.V130.Suppl_1.173.173
Published: 2017
Journal Articles

Influential Role of Macrophages in Hepcidin Regulation in Apo-Transferrin Treated β-Thalassemic Mice

Daniel Moskop, Shuming Sun, PhD, Maria Feola, PhD, Marc Ruiz Martinez, PhD, Huiyong Chen, PhD, Jing Liu, PhD, Nathan Brinkman, PhD, Robert E Fleming, MD, Stefano Rivella, PhD, Yelena Ginzburg, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 172.
https://doi.org/10.1182/blood.V130.Suppl_1.172.172
Published: 2017
Journal Articles

Administration of Minihepcidins to Animals Affected By β-Thalassemia Major Reduces Anemia and Splenomegaly

Roberta Chessa, PhD, Ritama Gupta, MSc, Carla Casu, PhD, Robert E Fleming, MD, Yelena Ginzburg, Brian MacDonald, MB, ChB, PhD, Stefano Rivella, PhD
Journal: Blood
Blood (2016) 128 (22): 259.
https://doi.org/10.1182/blood.V128.22.259.259
Published: 2016
Journal Articles

Hepcidin and Atoh8 mRNA Expression Are Decreased in Murine Models of Hemochromatosis However Hepcidin Expression Is Unaffected By Atoh8 Knockout

Robert E Fleming, MD, Yihang Li, PhD, Ian Miller, BS, Princy Prasad, MS, Andrew McKie, PhD
Journal: Blood
Blood (2015) 126 (23): 947.
https://doi.org/10.1182/blood.V126.23.947.947
Published: 2015
Journal Articles

Peroxisome Proliferator-Activated Receptor Alpha Contributes to Hepcidin up-Regulation in Mice during Fasting

Yihang Li, PhD, Princy Prasad, MS, Ian Miller, BS, Cedric Langhi, PhD, Angel Baldan, PhD, Robert E Fleming, MD
Journal: Blood
Blood (2015) 126 (23): 948.
https://doi.org/10.1182/blood.V126.23.948.948
Published: 2015
Journal Articles

Down-Regulation of TfR1 Increases Erythroid Precursor Enucleation and Hepatocyte Hepcidin Expression in ß-Thalassemic Mice

Huihui Li, MS, Tenzin Choesang, MS, Weili Bao, MS, Lionel Blanc, PhD, Huiyong Chen, PhD, Maria Feola, MS, Jie Li, MD, Guiyuan Li, MD, Shuming Sun, PhD, Antonia Follenzi, MDPhD, Petra Pham, MS, Xiuli An, MD PhD, Narla Mohandas, DSc, Robert E Fleming, MD, Stefano Rivella, PhD, Yelena Ginzburg, MD
Journal: Blood
Blood (2015) 126 (23): 754.
https://doi.org/10.1182/blood.V126.23.754.754
Published: 2015
Journal Articles

Increased Hepcidin Expression in β-Thalassemic Mice Treated with Apo-Transferrin Is Associated with Increased Smad1/5/8 and Decreased Erk1/2 Pathway Activation

Huiyong Chen, PhD, Tenzin Choesang, Petra Pham, Weili Bao, Maria Feola, Huihui Li, MS, Mark Westerman, PhD, Guiyuan Li, Antonia Follenzi, Lionel Blanc, PhD, Stefano Rivella, PhD, Robert E Fleming, MD, Yelena Ginzburg, MD
Journal: Blood
Blood (2014) 124 (21): 747.
https://doi.org/10.1182/blood.V124.21.747.747
Published: 2014
Journal Articles

Hypoferremia of Fasting in Mice Is Associated with Increased Hepcidin and Decreased Erythroferrone Expression

Yihang Li, PhD, Gregory R Booth, MD, Qi Feng, MD, Robert E Fleming, MD
Journal: Blood
Blood (2014) 124 (21): 4026.
https://doi.org/10.1182/blood.V124.21.4026.4026
Published: 2014
Journal Articles

Exogenous Apo-Transferrin Increases Monoferric Transferrin, Decreasing Cytosolic Iron Uptake and Heme and Globin Synthesis in β-Thalassemic Mice

Tenzin Choesang, Huihui Li, MS, Michael Dussiot, Thiago Maciel, PhD, Laura Breda, PhD, Daniel Garcia Santos, PhD, Huiyong Chen, PhD, Maria Feola, Weili Bao, Petra Pham, Antonia Follenzi, Guiyuan Li, Ivan Cruz Moura, PhD, Prem Ponka, MD PhD, Robert E Fleming, MD, Stefano Rivella, PhD, Yelena Ginzburg, MD
Journal: Blood
Blood (2014) 124 (21): 4037.
https://doi.org/10.1182/blood.V124.21.4037.4037
Published: 2014
Journal Articles

Upregulation Of Hepcidin Expression By Lactoferrin Administration To Pre-Weanling Mice

Memisoglu Elif, BS, Jeffrey A. Cooper, MD, Robert E. Fleming, MD
Journal: Blood
Blood (2013) 122 (21): 964.
https://doi.org/10.1182/blood.V122.21.964.964
Published: 2013