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Journal Articles

Development of a Neoantigen Prediction Tool for Patient Stratification in Immuno-Oncology Trials

Daniel Duncan, MD, Venkata Thodima, PhD, Jack Yen, MS, Samir Parekh, MD, Alessandro Lagana, PhD, Rita Shaknovich, MD PhD

Blood (2018) 132 (Supplement 1): 2215.

https://doi.org/10.1182/blood-2018-99-119094

Published: 2018

Journal Articles

Precision in PD-L1 Assessment in Diffuse Large B Cell Lymphoma: Greater Biological Insight Using in Situ Hybridization Approach

Imran Siddiqi, MDPhD, Venkata Thodima, PhD, Kishor Bhatia, PhD, Jane Houldsworth, PhD, Rita Shaknovich, MD PhD

Blood (2017) 130 (Supplement 1): 1477.

https://doi.org/10.1182/blood.V130.Suppl_1.1477.1477

Published: 2017

Journal Articles

DLBCL-Derived Exosomes Provide Key Insights into Genomic Landscape in Cell of Origin and May Lead to a Novel Method of Surveillance and Therapeutic Intervention

Sarah C Rutherford, MD, Angela Fachel, PhD, Sheng Li, PhD, Yanwen Jiang, Maria Pilar Dominguez, PhD, Doron Betel, PhD, Rita Shaknovich, MD PhD

Blood (2017) 130 (Supplement 1): 5132.

https://doi.org/10.1182/blood.V130.Suppl_1.5132.5132

Published: 2017

Journal Articles

PD-L1 Expression Identifies High Risk Diffuse Large B-Cell Lymphoma and Is Associated with Several Genomic Markers

Imran N Siddiqi, MD PhD, Venkata Thodima, PhD, Julia Friedman, PhD, Adames Violeta, Anil Tulpule, MD, Rita Shaknovich, MD PhD, Jane Houldsworth, PhD

Blood (2016) 128 (22): 153.

https://doi.org/10.1182/blood.V128.22.153.153

Published: 2016

Journal Articles

AICDA Introduces Epigenetic Plasticity in Germinal Center-Derived Lymphomas and Accelerates Lymphomagenesis

Maria Del Pilar Dominguez, PhD, Matt Teater, M.S., David Redmond, Zhengming Cheng, PhD, Jayanta Chaudhuri, PhD, Olivier Elemento, PhD, Ari Melnick, MD, Rita Shaknovich, MD PhD

Blood (2016) 128 (22): 1045.

https://doi.org/10.1182/blood.V128.22.1045.1045

Published: 2016

Journal Articles

Crebbp Mutations Disrupt Dynamic Enhancer Acetylation in B-Cells, Enabling HDAC3 to Drive Lymphomagenesis

Blood (2016) 128 (22): 735.

https://doi.org/10.1182/blood.V128.22.735.735

Published: 2016

Journal Articles

SOX11 Cooperates with CCND1 in Mantle Cell Lymphoma Pathogenesis

Pei-Yu Kuo, MS, Zewei Jiang, MD, Deepak Perumal, PhD, Violetta V Leshchenko, PhD, Alessandro Lagana', PhD, Samuel G. Katz, MD PhD, Loren D. Walensky, MD PhD, Rita Shaknovich, MD, PhD, B. Hilda Ye, PhD, Samir Parekh, MD

Blood (2015) 126 (23): 1253.

https://doi.org/10.1182/blood.V126.23.1253.1253

Published: 2015

Journal Articles

Characterization of DLBCL-Derived Exosomes and Investigation of Their Biological Properties

Sarah C. Rutherford, MD, Seema Sawh, Ashish Saxena, MD PhD, Jennifer Ishii, Maria D. Dominguez, PhD, Nyasha Chambwe, PhD, Eloisi Caldas Lopes, PhD, Xabier Agirre, PhD, Doron Betel, PhD, Rita Shaknovich, MD PhD

Blood (2014) 124 (21): 3021.

https://doi.org/10.1182/blood.V124.21.3021.3021

Published: 2014

Journal Articles

Mirna-181a expression Lead to Longer Animal Survival and Slower Tumor-Growth Rate in Diffuse Large B-Cell Lymphoma Xenograft Models

Goldi A Kozloski, PhD, Xiaoyu Jiang, PhD, Shruti Bhatt, PhD, Rita Shaknovich, MD PhD, Ari M Melnick, MD, Izidore S Lossos, MD

Blood (2014) 124 (21): 2963.

https://doi.org/10.1182/blood.V124.21.2963.2963

Published: 2014

Journal Articles

Demethylase Activity of Aid during Germinal Center B Cell Maturation Could Contribute to Lymphomagenesis

Maria Del Pilar Dominguez, PhD, Matt Teater, Nyasha Chambwe, PhD, David Redmond, Bao Vuong, PhD, Jayanta Chaudhuri, PhD, Olivier Elemento, PhD, Rita Shaknovich, MD PhD

Blood (2014) 124 (21): 59.

https://doi.org/10.1182/blood.V124.21.59.59

Published: 2014

Journal Articles

EZH2 and BCL6 Cooperate To Create The Germinal Center B-Cell Phenotype and Induce Lymphomas Through Formation and Repression Of Bivalent Chromatin Domains

Wendy Béguelin, PhD, Matt R. Teater, MS, Katerina Hatzi, PhD, Relja Popovich, PhD, Yanwen Jiang, PhD, Karen L. Bunting, PhD, Monica Rosen, Hao Shen, MD, Shao Ning Yang, Young Rock Chung, MSc, Rita Shaknovich, MD/PhD, Caretha Creasy, Randy D. Gascoyne, MD, Leandro Cerchietti, MD, Ross L. Levine, MD, Omar Abdel-Wahab, MD, Jonathan D. Licht, MD, Olivier Elemento, PhD, Ari M. Melnick, MD

Blood (2013) 122 (21): 1.

https://doi.org/10.1182/blood.V122.21.1.1

Published: 2013

Journal Articles

Epigenomic Evolution In Diffuse Large B-Cell Lymphomas

Heng Pan, BA, Yanwen Jiang, PhD, David Redmond, Kui Nie, PhD, Leandro Cerchietti, MD, Rita Shaknovich, MD/PhD, Ari M. Melnick, MD, Wayne Tam, MD, PhD, Olivier Elemento, PhD

Blood (2013) 122 (21): 634.

https://doi.org/10.1182/blood.V122.21.634.634

Published: 2013

Journal Articles

IL10 Receptor a Is a Novel Therapeutic Target That Is Epigenetically Disregulated in Low Grade Lymphomas with Plasmacytic Differentiation.

Wendy Beguelin, Ph.D., Alisa Chalmers, Lucas Tsikitas, Wayne Tam, MD, PhD, Govind Bhagat, MD, Rita Shaknovich, MD/PhD

Blood (2012) 120 (21): 2383.

https://doi.org/10.1182/blood.V120.21.2383.2383

Published: 2012

Journal Articles

Three-Dimensional Reorganization of the Genome During B Cell Affinity Maturation

Karen L. Bunting, PhD, David Soong, PhD, Yanwen Jiang, PhD, Brandon L. Swed, Katerina Hatzi, PhD, Rita Shaknovich, MD/PhD, William Reisacher, MD, Olivier Elemento, PhD, Ari Melnick, MD

Blood (2012) 120 (21): 279.

https://doi.org/10.1182/blood.V120.21.279.279

Published: 2012

Journal Articles

Epigenetic Profiling of Primary CLL Reveals Novel DNA Methylation-Based Clusters and Novel Mechanisms of Leukemogenesis

Fong Fong, M.D./Ph.D., Haim Y Bar, Ph.D., Kerby Shedden, PhD, Kamlai saiya-Cork, Peter Ouillette, Fabien Campagne, Ph.D., Ari Melnick, MD, Sami Malek, MD, Rita Shaknovich, MD/PhD

Blood (2012) 120 (21): 3877.

https://doi.org/10.1182/blood.V120.21.3877.3877

Published: 2012

Journal Articles

Differential DNA Methylation of TUBB1 Correlates with Tissue-Specific Hβ-1 Tubulin Expression

Paul Andrew Basciano, MD, Rita Shaknovich, MD/PhD, Maria E Figueroa, MD, Paraskevi Giannakakou, PhD

Blood (2011) 118 (21): 4796.

https://doi.org/10.1182/blood.V118.21.4796.4796

Published: 2011

Journal Articles

Epigenetic Profiling of Primary DLBCLs Reveals Novel DNA Methylation-Based Clusters and New Underlying Mechanisms of Lymphomagenesis

Nyasha Chambwe, BS, Matthias Kormaksson, Ph.D, Subhajyoti De, Ph.D., Franziska Michor, Ph.D., Nathalie Johnson, MD, David W Scott, MBChB PhD, Randy D. Gascoyne, MD, Ari Melnick, MD, Fabien Campagne, Ph.D., Rita Shaknovich, MD/PhD

Blood (2011) 118 (21): 556.

https://doi.org/10.1182/blood.V118.21.556.556

Published: 2011

Journal Articles

Chemosensitization of Diffuse Large B Cell Lymphoma by Demethylating Nucleoside Analogues

Thomas Clozel, MD, ShaoNing Yang, Ms, Matthias Kormaksson, PhD, Rebecca Elstrom, MD, Aparna Vasanthakumar, BSc, MSc, PhD, Sarah Brennan, PhD, Biljana Culjkovic, PhD, Michael Leser, Peter Martin, MD, Katherine LB Borden, PhD, Y. Lynn Wang, MD, PhD, Shuhua Cheng, PhD, Wayne Tam, MD, PhD, Rita Shaknovich, MD/PhD, Amy Chadburn, MD, Lucy Godley, MD, PhD, John P. Leonard, MD, Ari Melnick, MD, Leandro Cerchietti, MD

Blood (2011) 118 (21): 1617.

https://doi.org/10.1182/blood.V118.21.1617.1617

Published: 2011

Journal Articles

Genome-Wide Methylation Analysis of Primary Mantle Cell Lymphomas Identifies Novel Gene Targets for Epigenetic Drug Therapy.

Violetta Leshchenko, PhD, Pei-Yu Kuo, MS, Rita Shaknovich, MD, PhD, Tobias Gellen, Yvonne Remache, BS, Marc Weniger, PhD, K. Stephen Suh, PhD, Andre Goy, MD, Wyndham Wilson, MD, PhD, Ira Braunschweig, MD, Amit Verma, MD, Adrian Wiestner, MD, PhD, Ari Melnick, MD, Samir Parekh, MD

Blood (2009) 114 (22): 673.

https://doi.org/10.1182/blood.V114.22.673.673

Published: 2009

Journal Articles

EZH2 Mediates DNA Methylation-Independent Epigenetic Silencing of a Germinal Center Specific Transcriptional Program That Contributes to Cellular Proliferation and Lymphomagenesis.

Irina Velichutina, PhD, Rita Shaknovich, MD, PhD, Huimin Geng, Ari Melnick, Olivier Elemento, Ph.D.

Blood (2009) 114 (22): 3465.

https://doi.org/10.1182/blood.V114.22.3465.3465

Published: 2009

NARROW

Development of a Neoantigen Prediction Tool for Patient Stratification in Immuno-Oncology Trials

Precision in PD-L1 Assessment in Diffuse Large B Cell Lymphoma: Greater Biological Insight Using in Situ Hybridization Approach

DLBCL-Derived Exosomes Provide Key Insights into Genomic Landscape in Cell of Origin and May Lead to a Novel Method of Surveillance and Therapeutic Intervention

PD-L1 Expression Identifies High Risk Diffuse Large B-Cell Lymphoma and Is Associated with Several Genomic Markers

AICDA Introduces Epigenetic Plasticity in Germinal Center-Derived Lymphomas and Accelerates Lymphomagenesis

Crebbp Mutations Disrupt Dynamic Enhancer Acetylation in B-Cells, Enabling HDAC3 to Drive Lymphomagenesis

SOX11 Cooperates with CCND1 in Mantle Cell Lymphoma Pathogenesis

Characterization of DLBCL-Derived Exosomes and Investigation of Their Biological Properties

Mirna-181a expression Lead to Longer Animal Survival and Slower Tumor-Growth Rate in Diffuse Large B-Cell Lymphoma Xenograft Models

Demethylase Activity of Aid during Germinal Center B Cell Maturation Could Contribute to Lymphomagenesis

EZH2 and BCL6 Cooperate To Create The Germinal Center B-Cell Phenotype and Induce Lymphomas Through Formation and Repression Of Bivalent Chromatin Domains

Epigenomic Evolution In Diffuse Large B-Cell Lymphomas

IL10 Receptor a Is a Novel Therapeutic Target That Is Epigenetically Disregulated in Low Grade Lymphomas with Plasmacytic Differentiation.

Three-Dimensional Reorganization of the Genome During B Cell Affinity Maturation

Epigenetic Profiling of Primary CLL Reveals Novel DNA Methylation-Based Clusters and Novel Mechanisms of Leukemogenesis

Differential DNA Methylation of TUBB1 Correlates with Tissue-Specific Hβ-1 Tubulin Expression

Epigenetic Profiling of Primary DLBCLs Reveals Novel DNA Methylation-Based Clusters and New Underlying Mechanisms of Lymphomagenesis

Chemosensitization of Diffuse Large B Cell Lymphoma by Demethylating Nucleoside Analogues

Genome-Wide Methylation Analysis of Primary Mantle Cell Lymphomas Identifies Novel Gene Targets for Epigenetic Drug Therapy.

EZH2 Mediates DNA Methylation-Independent Epigenetic Silencing of a Germinal Center Specific Transcriptional Program That Contributes to Cellular Proliferation and Lymphomagenesis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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