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Ramasamy Jagadeeswaran, PhD
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Journal Articles

The Impact of Selenium Deficiency on a Sickle Cell Disease Mouse Model

Ramasamy Jagadeeswaran, PhD, Hong Lenny, PhD, Helen Zhang, Jennifer Afranie-Sakyi, Robert E. Molokie, MD, Donald Lavelle, PhD, Alan Diamond, PhD, Angela Rivers, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3645.
https://doi.org/10.1182/blood-2018-99-111833
Published: 2018
Journal Articles

The LSD1 Inhibitor RN-1 Increases γ-Globin Expression in Baboons By Targeting an Early Event Responsible for γ-Globin Repression

Kestis Vaitkus, Vinzon Ibanez, B.S., Maria Armila Ruiz, B.S., Ramasamy Jagadeeswaran, PhD, Yogenthiran Saunthararajah, MD, James Douglas Engel, PhD, Joseph DeSimone, PhD, Angela Rivers, MD, Donald Lavelle, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1054.
https://doi.org/10.1182/blood-2018-99-113539
Published: 2018
Journal Articles

The Abnormal Presence of Mitochondria in Circulating Red Blood Cells Cause an Increased Oxygen Consumption Rate, ROS Generation and Hemolysis in Patients with Sickle Cell Disease

Ramasamy Jagadeeswaran, PhD MSc, Hong Lenny, PhD, Benjamin Vazquez, BA, Joshua Muniz, BS, Aimee Schad, Shivi Jain, MD, Michel Gowhari, DO, Donald Lavelle, PhD, Alan Diamond, PhD, Robert E. Molokie, MD, Angela Rivers, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2237.
https://doi.org/10.1182/blood.V130.Suppl_1.2237.2237
Published: 2017
Journal Articles

Oral Administration of the LSD1 Inhibitor OG-S1335 Increases Fetal Hemoglobin in Humanized Transgenic Sickle Cell Disease Mice and in Baboons

Angela Rivers, MD PhD, Kestis Vaitkus, Ramasamy Jagadeeswaran, PhD MSc, Vinzon Ibanez, B.S., Maria Armila Ruiz, B.S., Filippo Ciceri, PhD, Fernando Cavalcanti, PhD, Robert E. Molokie, MD, Donald Lavelle, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 356.
https://doi.org/10.1182/blood.V130.Suppl_1.356.356
Published: 2017
Journal Articles

Mitophagy Induction Is a Potential Therapeutic Approach for Sickle Cell Disease

Ramasamy Jagadeeswaran, PhD, Benjamin Alejandro Vazquez, BS, Vinzon Ibanez, Maria A Ruiz, Robert E Molokie, MD, Joseph DeSimone, PhD, Donald Lavelle, PhD, Angela Rivers, MD PhD
Journal: Blood
Blood (2016) 128 (22): 267.
https://doi.org/10.1182/blood.V128.22.267.267
Published: 2016
Journal Articles

Investigation of Two Combination HbF Induction Regimens, RN-1 and Hydroxyurea Versus RN-1 and Decitabine, in a Humanized Sickle Cell Mouse Model

Ramasamy Jagadeeswaran, PhD, Yash Agarwal, Vinzon Ibanez, Maria Armila Ruiz, Kestis Vaitkus, Joseph DeSimone, PhD, Donald Lavelle, PhD, Angela Rivers, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3386.
https://doi.org/10.1182/blood.V126.23.3386.3386
Published: 2015