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Journal Articles

Biased PAR-1 Signaling Regulates Thrombo-Inflammation in a Mouse Model of Sickle Cell Disease

Erica Sparkenbaugh, PhD, John H. Griffin, PhD, Laurent O Mosnier, Rafal Pawlinski, PhD

Blood (2020) 136 (Supplement 1): 16–17.

https://doi.org/10.1182/blood-2020-139862

Published: 2020

Journal Articles

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

Michael Wayne Henderson, MSc, Erica Sparkenbaugh, PhD BS, Denis Noubouossie, MD PhD, Reiner Mailer, Thomas Renne, MD PhD, Keith R McCrae, MD, Nigel S. Key, MBChB, FRCP, Rafal Pawlinski, PhD

Blood (2019) 134 (Supplement_1): 3621.

https://doi.org/10.1182/blood-2019-127206

Published: 2019

Journal Articles

Thrombin-Mediated Activation of PAR-1 Contributes to Microvascular Stasis in Mouse Models of Sickle Cell Disease Via Increased Endothelial Expression of P-Selectin and VWF

Erica Sparkenbaugh, PhD BS, Chunsheng Chen, MD, Julia Nguyen, BS, Shaobin Wang, PhD, Gregory M. Vercellotti, MD, John D Belcher, PhD, Rafal Pawlinski, PhD

Blood (2018) 132 (Supplement 1): 266.

https://doi.org/10.1182/blood-2018-99-116238

Published: 2018

Journal Articles

High Molecular Weight Kininogen Contributes to End-Organ Damage and Mortality in a Mouse Model of Sickle Cell Disease

Erica Sparkenbaugh, PhD BS, Kathryn Wilson, BS, Malgorzata Kasztan, PhD, David M. Pollock, PhD, Keith R. McCrae, MD, Rafal Pawlinski, PhD

Blood (2018) 132 (Supplement 1): 268.

https://doi.org/10.1182/blood-2018-99-116526

Published: 2018

Journal Articles

Upregulation of Tissue Factor May Contribute to Thrombosis in Polycythemia Vera and Essential Thrombocythemia

Brandi Reeves, MD, Soo Jin Kim, MS, Jihyun Song, PhD, Radhika Gangaraju, MD, Rafal Pawlinski, PhD, Perumal Thiagarajan, MD, Victor R. Gordeuk, MD, Nigel S. Key, MBChB, FRCP, Josef T. Prchal, MD

Blood (2018) 132 (Supplement 1): 2513.

https://doi.org/10.1182/blood-2018-99-117812

Published: 2018

Journal Articles

FXIIa Differentially Regulates Thrombin Generation during Steady State and Vaso-Occlusive Crisis in Sickle Cell Mice

Erica M Sparkenbaugh, PhD, Camille Faes, PhD, Denis Noubouossie, MD PhD, Daniel K. Kirchhofer, PhD, András Gruber, MD, Nigel S. Key, MB, ChB, Rafal Pawlinski, PhD

Blood (2016) 128 (22): 162.

https://doi.org/10.1182/blood.V128.22.162.162

Published: 2016

Journal Articles

Alteration of the Structure and Dynamics of Venous Clot Formation in Human and Murine Sickle Cell Disease

Camille Faes, PhD, Anton Ilich, MD, Erica M Sparkenbaugh, PhD, Alisa S. Wolberg, PhD, Brian C. Cooley, PhD, Kenneth I. Ataga, MD, Nigel S. Key, MB, ChB, FRCP,, Rafal Pawlinski, PhD

Blood (2016) 128 (22): 2478.

https://doi.org/10.1182/blood.V128.22.2478.2478

Published: 2016

Journal Articles

Protease Activated Receptor 2 (PAR-2) Promotes Vascular Inflammation in a Mouse Model of Sickle Cell Disease

Pichika Chantrathammachart, MD, Erica M Sparkenbaugh, PhD, BS, Nigel Mackman, PhD, Nigel S Key, MBChB, Rafal Pawlinski, PhD

Blood (2012) 120 (21): 375.

https://doi.org/10.1182/blood.V120.21.375.375

Published: 2012

Journal Articles

Heme Induces Systemic Activation of Coagulation in Vivo in a Tissue Factor-Dependent Manner

Erica M Sparkenbaugh, PhD, BS, Pichika Chantrathammachart, MD, Nigel Mackman, PhD, Nigel S Key, MBChB, Rafal Pawlinski, PhD

Blood (2012) 120 (21): 820.

https://doi.org/10.1182/blood.V120.21.820.820

Published: 2012

Journal Articles

Generation of Floxed Tissue Factor Mice.

Rafal Pawlinski, PhD, Brian Pedersen, BS, Michael Tencati, BS, Nigel Mackman, PhD

Blood (2004) 104 (11): 3976.

https://doi.org/10.1182/blood.V104.11.3976.3976

Published: 2004

Journal Articles

The Synthetic Pentasaccharide, Fondaparinux, Reduces Inflammation and Neutrophil Accumulation in Kidney Ischemia-Reperfusion Injury.

Gernot Schabbauer, PhD, Rolf D. Frank, MD, Todd Holscher, BSc, Yuichiro Sato, MD, PhD, Michael Tencati, BSc, Rafal Pawlinski, PhD, Nigel Mackman, PhD

Blood (2004) 104 (11): 217.

https://doi.org/10.1182/blood.V104.11.217.217

Published: 2004

NARROW

Biased PAR-1 Signaling Regulates Thrombo-Inflammation in a Mouse Model of Sickle Cell Disease

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

Thrombin-Mediated Activation of PAR-1 Contributes to Microvascular Stasis in Mouse Models of Sickle Cell Disease Via Increased Endothelial Expression of P-Selectin and VWF

High Molecular Weight Kininogen Contributes to End-Organ Damage and Mortality in a Mouse Model of Sickle Cell Disease

Upregulation of Tissue Factor May Contribute to Thrombosis in Polycythemia Vera and Essential Thrombocythemia

FXIIa Differentially Regulates Thrombin Generation during Steady State and Vaso-Occlusive Crisis in Sickle Cell Mice

Alteration of the Structure and Dynamics of Venous Clot Formation in Human and Murine Sickle Cell Disease

Protease Activated Receptor 2 (PAR-2) Promotes Vascular Inflammation in a Mouse Model of Sickle Cell Disease

Heme Induces Systemic Activation of Coagulation in Vivo in a Tissue Factor-Dependent Manner

Generation of Floxed Tissue Factor Mice.

The Synthetic Pentasaccharide, Fondaparinux, Reduces Inflammation and Neutrophil Accumulation in Kidney Ischemia-Reperfusion Injury.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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