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Journal Articles

Impact of Race/Ethnicity on Pediatric Core Binding Factor AML Outcomes and Response to Gemtuzumab Ozogamicin

Shannon E. Conneely, MD, Casey L. McAtee, MD, Rachel E. Rau, MD

Blood (2020) 136 (Supplement 1): 10–11.

https://doi.org/10.1182/blood-2020-138890

Published: 2020

Journal Articles

Effects of Race and Ethnicity on Clinical Features, Tumor Genetics and Outcome in Children with KMT2A Rearranged Acute Myeloid Leukemia

Casey L. McAtee, MD, Joseph Lubega, MBChB, MPH, Michael E. Scheurer, PhD MPH, Rachel E. Rau, MD

Blood (2020) 136 (Supplement 1): 34.

https://doi.org/10.1182/blood-2020-136737

Published: 2020

Journal Articles

Open-Label, Multicenter, Phase 2/3 Study of Recombinant Crisantaspase Produced in Pseudomonas Fluorescens ( RC-P) in Patients with Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL) Following Hypersensitivity to Escherichia coli -Derived Asparaginases

Luke Maese, DO, Rachel E. Rau, MD, Elizabeth A. Raetz, MD, Tong Lin, Jin Zhu, Pil Kim, Reddy Chandula, Sherrie McClung, Julie Gray, Mi Rim Choi, MD, Mignon L. Loh, MD, Peter C. Adamson

Blood (2019) 134 (Supplement_1): 2586.

https://doi.org/10.1182/blood-2019-123710

Published: 2019

Journal Articles

Targeting Activated Signaling Pathways for the Treatment of IKZF1 -Deleted B Lymphoblastic Leukemia

Rohit Gupta, BA, Jason H. Rogers, MS, Xin Long, PhD, Geraldo Medrano, BS, Jaime M. Reyes, BS, Michele Redell, MD PhD, Zachary T Ball, PhD, Margaret Goodell, PhD, Rachel E. Rau, MD

Blood (2019) 134 (Supplement_1): 3789.

https://doi.org/10.1182/blood-2019-127209

Published: 2019

Journal Articles

A Novel Short Latency, High Penetrance Model of KRAS Mutation-Driven T-Cell Acute Lymphoblastic Leukemia

Jacob J. Junco, PhD, Vincent Ulysses Gant, PhD, Maci S. Terrell, BS, Matthew Benjamin Miller, MD, Chun Shik Park, PhD, Taylor J Chen, BS, H. Daniel Lacorazza, PhD, Margaret Goodell, PhD, Rachel E. Rau, MD, Karen R. Rabin, MD PhD

Blood (2019) 134 (Supplement_1): 3792.

https://doi.org/10.1182/blood-2019-126858

Published: 2019

Journal Articles

Precise Modeling of IKZF1 Alterations in Human B-Cell Acute Lymphoblastic Leukemia Cell Lines Reveals Distinct Chemosensitivity, Homing, and Engraftment Properties

Jason H. Rogers, MS, Rohit Gupta, BS, Jaime M. Reyes, BS, Lorenzo Brunetti, MD PhD, Michael C. Gundry, BS, Tidie Song, Cade Johnson, Carlo D. D. Cristobal, BS, Margaret A. Goodell, PhD, Rachel E. Rau, MD

Blood (2018) 132 (Supplement 1): 549.

https://doi.org/10.1182/blood-2018-99-113056

Published: 2018

Journal Articles

Phase I Study of the Selinexor in Relapsed/Refractory Childhood Acute Leukemia

Andrew E. Place, MD PhD, Traci M. Blonquist, MS, Elliot Stieglitz, MD, Todd M Cooper, DO, Lia Gore, MD, Richard Aplenc, MD PhD, Mignon L. Loh, MD, Melinda Pauly, MD, Rachel E. Rau, MD, Michael J. Burke, MD, Julia Etchin, PhD, A. Thomas Look, MD, Maria Luisa Sulis, MD, Lewis B. Silverman, MD

Blood (2018) 132 (Supplement 1): 1405.

https://doi.org/10.1182/blood-2018-99-116689

Published: 2018

Journal Articles

Mosaic DNMT3A Germline Mutation As a Model for Mutant DNMT3A Competitive Advantage in the Blood Lineage

Ayala Tovy, PhD, Hyun Jung Park, PhD, Jaime M. Reyes, BS, Anna Guzman, Rachel E. Rau, MD, Aaron Jeffries, PhD, Mill Jonnathan, PhD, Emma Baple, PhD, Andrew Crosby, MD, Mia Petljak, Henry Lee-Six, PhD, Heng Wang, MD PhD, Xin Baozhong, MD PhD, Mathijs A. Sanders, PhD, Peter J. Campbell, PhD, Michael Stratton, Wei Li, Margaret Goodell, PhD

Blood (2018) 132 (Supplement 1): 173.

https://doi.org/10.1182/blood-2018-173

Published: 2018

Journal Articles

Vitamin K3 (menadione) Induces Cytotoxicity in Chronic Myeloid Leukemia Stem Cells By Upregulating DYRK2 through the Inhibition of SIAH2 Ubiquitin Ligase

Chun Shik Park, PhD, Ye Shen, PhD, Andrew H Lewis, BS, Koramit Suppipat, MD, Monica Puppi, Julie Tomolonis, Taylor J Chen, Paul Pang, Toni-Ann Mistretta, Leyuan Ma, Michael R Green, PhD, Rachel E. Rau, MD, H. Daniel Lacorazza, PhD

Blood (2017) 130 (Supplement 1): 4171.

https://doi.org/10.1182/blood.V130.Suppl_1.4171.4171

Published: 2017

Journal Articles

Leukemia Fusion Gene Detection in the Clinical Molecular Laboratory Using RNA-Based Targeted Next-Generation Sequencing

Kevin E. Fisher, MD PhD, Jacquelyn Reuther, PhD, Hadi Sayeed, MS, Erica Fang Tam, MS, Vijetha Kumar, MS, Lizmery Suarez Ferguson, MS, Jyotinder Nain Punia, MD, Maria Monica Gramatges, MD PhD, Rachel E. Rau, MD, Karen R. Rabin, MD PhD, Dolores H. Lopez-Terrada, MD PhD, Angshumoy Roy, MD PhD

Blood (2016) 128 (22): 4074.

https://doi.org/10.1182/blood.V128.22.4074.4074

Published: 2016

Journal Articles

Aberrant Precursor B Lymphoid Blast Population in a Patient with Juvenile Myelomonocytic Leukemia

Saman Khalid Hashmi, MD, Jyotinder Nain Punia, MD, Amos S. Gaikwad, PhD, Kevin E. Fisher, MD PhD, Angshumoy Roy, MD PhD, Dolores H. Lopez-Terrada, MD PhD, Pulivarthi Rao, PhD, Jo Ringrose, CG(ASCP), Andrea N. Marcogliese, MD, Rachel E Rau, MD

Blood (2016) 128 (22): 5557.

https://doi.org/10.1182/blood.V128.22.5557.5557

Published: 2016

Journal Articles

A Wilms Tumor 1 (WT1) Mutation Causes Myelodysplastic Syndrome in a Knock-in Mouse Model, and a Mixed Myelodysplastic/Myeloproliferative Neoplam in Double Knock-in Mice with WT1 and FLT3/ITD Mutations

Colleen E. Annesley, MD, Amy S. Duffield, MD PhD, Rachel E. Rau, MD, Gregory McCarty, Daniel Magoon, Li Li, MD PhD, Vicki Huff, PhD, Donald Small, MD PhD, David Loeb, MD PhD, Patrick Brown, MD

Blood (2015) 126 (23): 312.

https://doi.org/10.1182/blood.V126.23.312.312

Published: 2015

Journal Articles

Poorer Relapse-Free Survival in Hispanic Children Diagnosed with Acute Myeloid Leukemia Compared with Non-Hispanics: A Texas Single Institution Experience

Aditya Deshpande, Maria Monica Gramatges, MD PhD, Ghadir S. Sasa, MD, Philip J Lupo, PhD MPH, Rachel E Rau, MD, Michele S. Redell, MD PhD, Terzah M. Horton, MD PhD, Michael E Scheurer, PhD MPH, Karen R. Rabin, MD PhD

Blood (2015) 126 (23): 1312.

https://doi.org/10.1182/blood.V126.23.1312.1312

Published: 2015

Journal Articles

Targeting BCL6-Mediated Resistance to BCR-ABL Targeted Tyrosine Kinase Inhibitors (TKIs) in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL) through the Addition of Histone Deacetylase (HDAC) Inhibitors

Gordon Cohen, MD MPH, Colleen E. Annesley, MD, Rachel E. Rau, MD, Shannon Kelley, Daniel Magoon, Patrick Brown, MD

Blood (2015) 126 (23): 1277.

https://doi.org/10.1182/blood.V126.23.1277.1277

Published: 2015

Journal Articles

DOT1L As a Therapeutic Target for the Treatment of DNMT3A -Mutant Acute Myeloid Leukemia

Rachel E. Rau, MD, Min Luo, PhD, Benjamin Rodriguez, PhDBA, Mira Jeong, PhD, Allison Rosen, M.S., Lishing Deng, Yongcheng Song, PhD, Margaret A Goodell, PhD

Blood (2014) 124 (21): 614.

https://doi.org/10.1182/blood.V124.21.614.614

Published: 2014

Journal Articles

Leukemogenic Wilms Tumor 1 (WT1) Mutations Enhance Progenitor Self Renewal, Inhibit Terminal Myeloid Differentiation, and Influence Survival in a Mouse Model

Colleen E. Annesley, MD, Rachel E. Rau, MD, Daniel Magoon, BS, Gregory McCarty, David Loeb, MD PhD, Patrick Brown, MD

Blood (2014) 124 (21): 3572.

https://doi.org/10.1182/blood.V124.21.3572.3572

Published: 2014

Journal Articles

Next-Generation NAMPT Inhibitors For ALL Identified By Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens

Michael C. Wei, MD, PhD, Christina J. Matheny, PhD, Michael C. Bassik, PhD, Alicia J. Donnelly, PhD, Martin Kampmann, PhD, Masayuki Iwasaki, PhD, MSC, Obdulio Piloto, PhD, David E. Solow-Cordero, PhD, Donna Bouley, DVM, PhD, Rachel E. Rau, MD, Patrick Brown, MD, Michael T. McManus, PhD, Jonathan S. Weissman, PhD, Michael L. Cleary, MD

Blood (2013) 122 (21): 171.

https://doi.org/10.1182/blood.V122.21.171.171

Published: 2013

Journal Articles

Oncogenic Wilms Tumor 1 (WT1) Mutation Augments Hematopoietic Progenitor Cell Clonogenicity and Promotes Expansion Of The Long-Term Hematopoietic Stem Cell (LT-HSC) Compartment: Implications For WT1-Mediated Leukemogenesis

Colleen E. Annesley, MD, Rachel E. Rau, MD, Daniel Magoon, David Loeb, MD, PhD, Patrick Brown, MD

Blood (2013) 122 (21): 1269.

https://doi.org/10.1182/blood.V122.21.1269.1269

Published: 2013

Journal Articles

Dnmt3a-Deletion Accelerates FLT3-ITD Malignancies In Mice By Hypomethylation Of Enhancer Sites and Activating Stem Cell Programs; Implications For Therapy

Liubin Yang, Benjamin Rodriguez, Min Luo, Ph.D., Mira Jeong, Ph.D., David Ruau, Choladda V. Curry, MD, Xiaotian Zhang, B.S, Grant A Challen, PhD, Rachel E. Rau, MD, Berthold Gottgens, Ph.D., Wei Li, Ph.D., Margaret A. Goodell, PhD

Blood (2013) 122 (21): 595.

https://doi.org/10.1182/blood.V122.21.595.595

Published: 2013

Journal Articles

Chemotherapy-Induced CXCR4 Modulation Predicts the In Vivo Efficacy of Plerixafor As a Chemosensitizer in Acute Leukemia

Edward Allan R. Sison, MD, Daniel Magoon, Li Li, PhD, Rachel E. Rau, MD, Colleen E. Annesley, MD, Donald Small, MD, PhD, Patrick A. Brown, MD

Blood (2011) 118 (21): 1410.

https://doi.org/10.1182/blood.V118.21.1410.1410

Published: 2011

NARROW

Impact of Race/Ethnicity on Pediatric Core Binding Factor AML Outcomes and Response to Gemtuzumab Ozogamicin

Effects of Race and Ethnicity on Clinical Features, Tumor Genetics and Outcome in Children with KMT2A Rearranged Acute Myeloid Leukemia

Open-Label, Multicenter, Phase 2/3 Study of Recombinant Crisantaspase Produced in Pseudomonas Fluorescens ( RC-P) in Patients with Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL) Following Hypersensitivity to Escherichia coli -Derived Asparaginases

Targeting Activated Signaling Pathways for the Treatment of IKZF1 -Deleted B Lymphoblastic Leukemia

A Novel Short Latency, High Penetrance Model of KRAS Mutation-Driven T-Cell Acute Lymphoblastic Leukemia

Precise Modeling of IKZF1 Alterations in Human B-Cell Acute Lymphoblastic Leukemia Cell Lines Reveals Distinct Chemosensitivity, Homing, and Engraftment Properties

Phase I Study of the Selinexor in Relapsed/Refractory Childhood Acute Leukemia

Mosaic DNMT3A Germline Mutation As a Model for Mutant DNMT3A Competitive Advantage in the Blood Lineage

Vitamin K3 (menadione) Induces Cytotoxicity in Chronic Myeloid Leukemia Stem Cells By Upregulating DYRK2 through the Inhibition of SIAH2 Ubiquitin Ligase

Leukemia Fusion Gene Detection in the Clinical Molecular Laboratory Using RNA-Based Targeted Next-Generation Sequencing

Aberrant Precursor B Lymphoid Blast Population in a Patient with Juvenile Myelomonocytic Leukemia

A Wilms Tumor 1 (WT1) Mutation Causes Myelodysplastic Syndrome in a Knock-in Mouse Model, and a Mixed Myelodysplastic/Myeloproliferative Neoplam in Double Knock-in Mice with WT1 and FLT3/ITD Mutations

Poorer Relapse-Free Survival in Hispanic Children Diagnosed with Acute Myeloid Leukemia Compared with Non-Hispanics: A Texas Single Institution Experience

Targeting BCL6-Mediated Resistance to BCR-ABL Targeted Tyrosine Kinase Inhibitors (TKIs) in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL) through the Addition of Histone Deacetylase (HDAC) Inhibitors

DOT1L As a Therapeutic Target for the Treatment of DNMT3A -Mutant Acute Myeloid Leukemia

Leukemogenic Wilms Tumor 1 (WT1) Mutations Enhance Progenitor Self Renewal, Inhibit Terminal Myeloid Differentiation, and Influence Survival in a Mouse Model

Next-Generation NAMPT Inhibitors For ALL Identified By Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens

Oncogenic Wilms Tumor 1 (WT1) Mutation Augments Hematopoietic Progenitor Cell Clonogenicity and Promotes Expansion Of The Long-Term Hematopoietic Stem Cell (LT-HSC) Compartment: Implications For WT1-Mediated Leukemogenesis

Dnmt3a-Deletion Accelerates FLT3-ITD Malignancies In Mice By Hypomethylation Of Enhancer Sites and Activating Stem Cell Programs; Implications For Therapy

Chemotherapy-Induced CXCR4 Modulation Predicts the In Vivo Efficacy of Plerixafor As a Chemosensitizer in Acute Leukemia

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American Society of Hematology

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American Society of Hematology

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