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Journal Articles

Heme Synthesis Is Inhibited in Erythroid Cells Derived from Beta-Thalassemic Mice

Daniel Garcia dos Santos, PhD, Amel Hamdi, PhD, Prem Ponka, MD PhD

Blood (2017) 130 (Supplement 1): 3494.

https://doi.org/10.1182/blood.V130.Suppl_1.3494.3494

Published: 2017

Journal Articles

Role of Heme in the Regulation of Transferrin Receptor Expression in Erythroid Cells

Amel Hamdi, PhD, Daniel Garcia dos Santos, PhD, Chun-Nam Lok, PhD, Matthias Schranzhofer, PhD, Prem Ponka, MD PhD

Blood (2017) 130 (Supplement 1): 3495.

https://doi.org/10.1182/blood.V130.Suppl_1.3495.3495

Published: 2017

Journal Articles

Endosome-Mitochondria Interface Controls Intracellular Iron Trafficking in Erythroid Cells

Amel Hamdi, PhD, Daniel Garcia-Santos, PhD, Tariq Roshan, MD, Alex Sheftel, PhD, Prem Ponka, MD PhD FCMA

Blood (2016) 128 (22): 75.

https://doi.org/10.1182/blood.V128.22.75.75

Published: 2016

Journal Articles

Heme Oxygenase 1 Inhibition Reverses Anemia in β-Thalassemia Mice

Daniel Garcia-Santos, PhD, Amel Hamdi, PhD, Zuzana Zidova, MSc, Monika Horvathova, PhD, Prem Ponka, MD PhD FCMA

Blood (2016) 128 (22): 2462.

https://doi.org/10.1182/blood.V128.22.2462.2462

Published: 2016

Journal Articles

Pathophysiology and Treatment of Beta-Thalassemia: Investigations of Heme Oxygenase 1 and Its Inhibitors

Daniel Garcia dos Santos, PhD, Zuzana Zidova, MSc, Marc Mikhael, PhD, Amel Hamdi, PhD, Monika Horvathova, PhD, Prem Ponka, MD PhD FCMA

Blood (2015) 126 (23): 3373.

https://doi.org/10.1182/blood.V126.23.3373.3373

Published: 2015

Journal Articles

Transcriptional Induction of Transferrin Receptors By Heme in Erythroid Cells

Daniel Garcia dos Santos, PhD, Matthias Schranzhofer, MSc, PhD, Nam Lok Chun, PhD, Amel Hamdi, PhD, Prem Ponka, MD PhD FCMA

Blood (2015) 126 (23): 3352.

https://doi.org/10.1182/blood.V126.23.3352.3352

Published: 2015

Journal Articles

Interaction of Transferrin-Endosomes with Mitochondria: Implications for Iron Transport to Ferrochelatase in Erythroid Cells

Amel Hamdi, PhD, Tariq Roshan, MD, Alex Sheftel, PhD, Prem Ponka, MD PhD FCMA

Blood (2015) 126 (23): 407.

https://doi.org/10.1182/blood.V126.23.407.407

Published: 2015

Journal Articles

Further Elucidation of the Mechanism of Iron Transport Form Plasma Transferrin to Mitochondrial Ferrochelatase: Further Evidence for the “Kiss and Run” Hypothesis

Amel Hamdi, PhD, Tariq Roshan, MD, Alex Sheftel, PhD, Prem Ponka, MD PhD FCMA

Blood (2014) 124 (21): 4023.

https://doi.org/10.1182/blood.V124.21.4023.4023

Published: 2014

Journal Articles

Oxidative Stress and Increased Destruction of Red Blood Cells Contribute to the Pathophysiology of Anemia Caused By DMT1 Deficiency

Zuzana Zidova, MSc, Daniel Garcia-Santos, PhD, Katarina Kapralova, MSc, Pavla Koralkova, MSc, Renata Mojzikova, PhD, Dalibor Dolezal, DVM, Prem Ponka, MD PhD FCMA, Vladimir Divoky, PhD, Monika Horvathova, PhD

Blood (2014) 124 (21): 4027.

https://doi.org/10.1182/blood.V124.21.4027.4027

Published: 2014

Journal Articles

Exogenous Apo-Transferrin Increases Monoferric Transferrin, Decreasing Cytosolic Iron Uptake and Heme and Globin Synthesis in β-Thalassemic Mice

Tenzin Choesang, Huihui Li, MS, Michael Dussiot, Thiago Maciel, PhD, Laura Breda, PhD, Daniel Garcia Santos, PhD, Huiyong Chen, PhD, Maria Feola, Weili Bao, Petra Pham, Antonia Follenzi, Guiyuan Li, Ivan Cruz Moura, PhD, Prem Ponka, MD PhD, Robert E Fleming, MD, Stefano Rivella, PhD, Yelena Ginzburg, MD

Blood (2014) 124 (21): 4037.

https://doi.org/10.1182/blood.V124.21.4037.4037

Published: 2014

Journal Articles

Uncovering the Role of Heme Oxygenase 1 in the Pathophysiology of β-Thalassemia

Daniel Garcia-Santos, PhD, Marc Mikhael, PhD, Monika Horvathova, PhD, Prem Ponka, MD PhD

Blood (2014) 124 (21): 1364.

https://doi.org/10.1182/blood.V124.21.1364.1364

Published: 2014

Journal Articles

Heme Oxygenase 1 Plays a Role In The Pathophysiology Of β-Thalassemia

Daniel Garcia Santos, Ph.D., Marc Mikhael, PhD, Stefano Rivella, PhD, Monika Horvathova, PhD, Prem Ponka, MD, PhD

Blood (2013) 122 (21): 3449.

https://doi.org/10.1182/blood.V122.21.3449.3449

Published: 2013

Journal Articles

The Erythropoietin Receptor Regulates The Number Of Cell Divisions and The Duration Of Erythroblast Terminal Differentiation By Regulating Erythroblast Iron

Daniel Hidalgo, MA, Ramona Pop, Prem Ponka, MD, PhD, Merav Socolovsky, MBBS, PhD

Blood (2013) 122 (21): 428.

https://doi.org/10.1182/blood.V122.21.428.428

Published: 2013

Journal Articles

SNX3 Regulates Recycling of the Transferrin Receptor and Iron Assimilation in Developing Erythrocytes*

Blood (2012) 120 (21): 607.

https://doi.org/10.1182/blood.V120.21.607.607

Published: 2012

Journal Articles

Heme Oxygenase 1 Plays An Unexpected Role During Erythroid Differentiation

Daniel Garcia Santos, Phd, Matthias Schranzhofer, MSc, PhD, José Artur Bogo Chies, Msc, Phd, Prem Ponka, MD, PhD

Blood (2011) 118 (21): 344.

https://doi.org/10.1182/blood.V118.21.344.344

Published: 2011

Journal Articles

Glycine Transporter 1 Plays a Crucial Role in Hemoglobinization

Matthias Schranzhofer, MSc, PhD, Richard Bergeron, MD, PhD, Prem Ponka, MD, PhD

Blood (2011) 118 (21): 345.

https://doi.org/10.1182/blood.V118.21.345.345

Published: 2011

Journal Articles

Further Evidence for the “Kiss and Run” Hypothesis of Iron Delivery to Mitochondria in Erythroid Cells,

Tariq Roshan, MD, Tanya Kahawita, MSc, Matthias Schranzhofer, MSc, PhD, Marc Mikhael, PhD, Anne B Mason, Alex Sheftel, PhD, Prem Ponka, MD, PhD

Blood (2011) 118 (21): 3178.

https://doi.org/10.1182/blood.V118.21.3178.3178

Published: 2011

Journal Articles

Transcriptional Regulation of Transferrin Receptor by Heme in Erythroid Cells

Matthias Schranzhofer, MSc, PhD, Nam-Chun Lok, PhD, Manfred Schifrer, MSc, Ernst W Muellner, PhD, Prem Ponka, MD, PhD

Blood (2010) 116 (21): 2049.

https://doi.org/10.1182/blood.V116.21.2049.2049

Published: 2010

Journal Articles

Nitrogen Monoxide Inhibits Heme Synthesis In Reticulocytes

Marc Mikhael, PhD, Sameer Apte, BSc, Shan Soe-Lin, PhD, Prem Ponka, MD, PhD

Blood (2010) 116 (21): 4252.

https://doi.org/10.1182/blood.V116.21.4252.4252

Published: 2010

Journal Articles

Intraendosomal Transferrin Saturation Governs Interorganellar Association for Iron Delivery In Erythroid Cells

Tariq Roshan, MD, Tanya Kahawita, MSc, Matthias Schranzhofer, MSc, PhD, Marc Mikhael, PhD, Alex Sheftel, PhD, Prem Ponka, MD, PhD

Blood (2010) 116 (21): 4253.

https://doi.org/10.1182/blood.V116.21.4253.4253

Published: 2010

NARROW

Heme Synthesis Is Inhibited in Erythroid Cells Derived from Beta-Thalassemic Mice

Role of Heme in the Regulation of Transferrin Receptor Expression in Erythroid Cells

Endosome-Mitochondria Interface Controls Intracellular Iron Trafficking in Erythroid Cells

Heme Oxygenase 1 Inhibition Reverses Anemia in β-Thalassemia Mice

Pathophysiology and Treatment of Beta-Thalassemia: Investigations of Heme Oxygenase 1 and Its Inhibitors

Transcriptional Induction of Transferrin Receptors By Heme in Erythroid Cells

Interaction of Transferrin-Endosomes with Mitochondria: Implications for Iron Transport to Ferrochelatase in Erythroid Cells

Further Elucidation of the Mechanism of Iron Transport Form Plasma Transferrin to Mitochondrial Ferrochelatase: Further Evidence for the “Kiss and Run” Hypothesis

Oxidative Stress and Increased Destruction of Red Blood Cells Contribute to the Pathophysiology of Anemia Caused By DMT1 Deficiency

Exogenous Apo-Transferrin Increases Monoferric Transferrin, Decreasing Cytosolic Iron Uptake and Heme and Globin Synthesis in β-Thalassemic Mice

Uncovering the Role of Heme Oxygenase 1 in the Pathophysiology of β-Thalassemia

Heme Oxygenase 1 Plays a Role In The Pathophysiology Of β-Thalassemia

The Erythropoietin Receptor Regulates The Number Of Cell Divisions and The Duration Of Erythroblast Terminal Differentiation By Regulating Erythroblast Iron

SNX3 Regulates Recycling of the Transferrin Receptor and Iron Assimilation in Developing Erythrocytes*

Heme Oxygenase 1 Plays An Unexpected Role During Erythroid Differentiation

Glycine Transporter 1 Plays a Crucial Role in Hemoglobinization

Further Evidence for the “Kiss and Run” Hypothesis of Iron Delivery to Mitochondria in Erythroid Cells,

Transcriptional Regulation of Transferrin Receptor by Heme in Erythroid Cells

Nitrogen Monoxide Inhibits Heme Synthesis In Reticulocytes

Intraendosomal Transferrin Saturation Governs Interorganellar Association for Iron Delivery In Erythroid Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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