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Philip J. Fay, PhD
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Journal Articles

Stabilizing Factor VIIIa By Combining Mutations That Modulate Inter-Subunit Interactions and Proteolytic Inactivation

Hironao Wakabayashi, MD, PhD, Jennifer Wintermute, Philip J. Fay, PhD
Journal: Blood
Blood (2013) 122 (21): 3572.
https://doi.org/10.1182/blood.V122.21.3572.3572
Published: 2013
Journal Articles

Reduced Affinity To VWF Induced By a Novel Mutation At Pro1809Leu (factor VIII-Tenri) Is The Cause Of Mild Hemophilia A Developing Anti-Factor VIII Inhibitor

Koji Yada, MD, PhD, Keiji Nogami, MD, PhD, Masahiro Takeyama, MD, PhD, Hiroaki Minami, MD, Philip J. Fay, PhD, Midori Shima, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2343.
https://doi.org/10.1182/blood.V122.21.2343.2343
Published: 2013
Journal Articles

A Coagulation Mechanism for the Mild Bleeding Tendency in a Patient with Severe Hemophilia A Possessing an Arg1781His Mutation.

Koji Yada, MD, Keiji Nogami, MD, PhD, Kenichi Ogiwara, MD, PhD, Hironao Wakabayashi, MD, PhD, Philip J. Fay, PhD, Midori Shima, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2213.
https://doi.org/10.1182/blood.V120.21.2213.2213
Published: 2012
Journal Articles

Residues Surrounding Arg372, Arg740, and Arg1689 Contribute to the Rates of Thrombin-Catalyzed Cleavage of Factor VIII.

Jennifer L. Newell, PhD, Amy E. Griffiths, MS, Philip J. Fay, PhD
Journal: Blood
Blood (2009) 114 (22): 847.
https://doi.org/10.1182/blood.V114.22.847.847
Published: 2009
Journal Articles

Localization of Factor VIII Residues Contributing to Factor VIII and/or VIIIa Structural Stability as Detected by Rates of Activity Decay.

Hironao Wakabayashi, MD, PhD, Philip J. Fay, PhD
Journal: Blood
Blood (2007) 110 (11): 1763.
https://doi.org/10.1182/blood.V110.11.1763.1763
Published: 2007
Journal Articles

The Mutation Leu335Pro in Factor VIII Results in Its Rapid Inactivation by Thrombin-Catalyzed Proteolysis at Arg336.

Fatbardha Varfaj, Ph.D., Hironao Wakabayashi, Ph.D., Philip J. Fay, PhD
Journal: Blood
Blood (2007) 110 (11): 2690.
https://doi.org/10.1182/blood.V110.11.2690.2690
Published: 2007
Journal Articles

pH-Dependent Association of Factor VIII Chains: Enhancement of Affinity at Physiological pH by Cu 2+ .

Hironao Wakabayashi, MD, PhD, Qian Zhou, MS, Keiji Nogami, MD, Charles Ansong, MS, Fatbardha Varfaj, MS, Stephen Miles, PhD, Philip J. Fay, PhD
Journal: Blood
Blood (2005) 106 (11): 1015.
https://doi.org/10.1182/blood.V106.11.1015.1015
Published: 2005
Journal Articles

Mapping Factor VIIIa Inter-Subunit Interactions Using Chemical Modification and Zero-Length Cross-Linking.

Stephen M. Miles, PhD, Jan Freas, BS, Philip J. Fay, PhD
Journal: Blood
Blood (2005) 106 (11): 1016.
https://doi.org/10.1182/blood.V106.11.1016.1016
Published: 2005
Journal Articles

Factor VIII A2 Domain Residues 497–510 and 584–593 Comprise the R8B12 Epitope.

Charles Ansong, MS, Stephen Miles, PhD, Philip J. Fay, PhD
Journal: Blood
Blood (2005) 106 (11): 4028.
https://doi.org/10.1182/blood.V106.11.4028.4028
Published: 2005