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Paul Manley, PhD
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Journal Articles

Inhibition of Chronic Myeloid Leukemia Stem Cells by the Combination of the Hedgehog Pathway Inhibitor LDE225 with Nilotinib

Bin Zhang, David Irvine, Yin Wei Ho, Silvia Buonamici, PhD, Paul Manley, PhD, Tessa L. Holyoake, PhD, FRCP, FRCPath, Mhairi Copland, PhD, BSc, MRCP, FRCPath, Ravi Bhatia, MD
Journal: Blood
Blood (2010) 116 (21): 514.
https://doi.org/10.1182/blood.V116.21.514.514
Published: 2010
Journal Articles

Comparative in Vitro Cellular Data Alone Is Insufficient to Predict Clinical Responses and Guide Choice of BCR-ABL Inhibitor to Treat Imatinib-Resistant Chronic Myeloid Leukemia.

Pierre Laneuville, MD, FRCPC, Clifford DiLea, PharmD, Jürgen Mestan, Ophelia Yin, PhD, FCP, Richard C. Woodman, MD, Paul Manley, PhD
Journal: Blood
Blood (2009) 114 (22): 510.
https://doi.org/10.1182/blood.V114.22.510.510
Published: 2009
Journal Articles

The Functional Activity of the OCT-1 Protein Is Predictive of Molecular Response and Survival in CP-CML Patients Treated with Imatinib: A 5 Year Update of the TIDEL Trial.

Deborah L White, PhD, Verity A Saunders, Amity Frede, Phuong Dang, Stephanie Zrim, Michael Philip Osborn, MB, BS, Paul Manley, PhD, Timothy Hughes, MD
Journal: Blood
Blood (2009) 114 (22): 507.
https://doi.org/10.1182/blood.V114.22.507.507
Published: 2009
Journal Articles

Lyn Kinase Overexpression Is One of the Mechanisms of Resistance to Nilotinib In Chronic Myeloid Leukemia

Francois-Xavi er Mahon, Sandrine Hayette, Valerie Lagarde, Franck E Nicolini, MD, PhD, Francis Belloc, Cedric Leroy, Serge Roche, Paul Manley, PhD, Coralie Belanger, Gabriel Etienne, Jean-Max Pasquet
Journal: Blood
Blood (2008) 112 (11): 3181.
https://doi.org/10.1182/blood.V112.11.3181.3181
Published: 2008