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Journal Articles

Mitochondrial Complex I Inhibition with Iacs-010759 in T-ALL Preclinical Models

Natalia Baran, PhD, Jennifer Molina, PhD, Antonio Cavazos, MS, Karine Harutyunyan, PhD, Ningping Feng, PhD, Jason Gay, MS, Sujan Piya, PhD, Sriram Shanmuga Velandy, MS, Elias J. Jabbour, MD, Michael Andreeff, MD PhD, Stefano Tiziani, PhD, Adolfo A. Ferrando, MD PhD, Patrick Zweidler-McKay, MD PhD, M. Emilia Di Francesco, PhD, Joseph R. Marszalek, PhD, Marina Konopleva, MD PhD

Blood (2016) 128 (22): 4028.

https://doi.org/10.1182/blood.V128.22.4028.4028

Published: 2016

Journal Articles

Clinical Implementation of a Testing Algorithm for the Diagnosis of Ph-like B-Cell Acute Lymphoblastic Leukemia

Xinyan Lu, MD, Alexandra Reynolds, Sergej Konopleva, MD, Sa Wang, MD, Kathryn G. Roberts, PhD, Charles Mullighan, MBBS, MSc, MD, Guilin Tang, MD, Zhenya Tang, MD, Patrick Zweidler-McKay, MD PhD, Jeffrey L. Jorgensen, MD PhD, Keyur P. Patel, MD PhD, L. Jeffrey Medeiros, MD, Pei Lin, MD, Marina Konopleva, MD PhD, Nitin Jain, MD

Blood (2016) 128 (22): 2915.

https://doi.org/10.1182/blood.V128.22.2915.2915

Published: 2016

Journal Articles

Outcomes of Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia Based on Blast Genotype at Diagnosis: A Report from the Children's Oncology Group

Blood (2016) 128 (22): 451.

https://doi.org/10.1182/blood.V128.22.451.451

Published: 2016

Journal Articles

Ex-Vivo Fucosylation Improves the Anti-Graft-Versus-Host-Disease Effects of Mesenchymal Stem Cells in the NOD/SCID/IL-2R Null Mouse Model

Jorge Galvez Silva, MD, Mayela Mendt Vilchez, PhD, Imahashi Nobuhiko, PhD, Bruce R. Blazar, MD, Patrick Zweidler-McKay, MD PhD, Katayoun Rezvani, MD, PhD, Elizabeth J. Shpall, MD

Blood (2016) 128 (22): 4559.

https://doi.org/10.1182/blood.V128.22.4559.4559

Published: 2016

Journal Articles

High-Risk Subtype of Ph-like Acute Lymphoblastic Leukemia (ALL) in Adults: Dismal Outcomes of CRLF2+ ALL Patients Treated with Intensive Chemotherapy

Blood (2016) 128 (22): 1082.

https://doi.org/10.1182/blood.V128.22.1082.1082

Published: 2016

Journal Articles

Targeting the NRF2/HO-1 Antioxidant Pathway with Consequences for Notch Signaling in FLT3-ITD Positive AML: A Novel Therapeutic Approach

Marisa J Hornbaker, B.S., Mary E Irwin, PhD, LaNisha Patterson, B.S., Shelley M Herbrich, MS, Patrick Zweidler-McKay, MD PhD, Joya Chandra, PhD

Blood (2015) 126 (23): 2470.

https://doi.org/10.1182/blood.V126.23.2470.2470

Published: 2015

Journal Articles

BRD4 Proteolysis Targeting Chimera (PROTAC) Leads to Sustained Degradation of BRD4 with Broad Activity Against Acute Leukemias and Overcomes Stroma Mediated Resistance By Modulating Surface Expression of CXCR4

Sujan Piya, Teresa McQueen, Duncan Mak, BSc, MPhil, Marina Konopleva, MD PhD, Patrick Zweidler-McKay, MD PhD, Jing Lu, PhD, Yimin Qian, PhD, Michael Andreeff, MD PhD, Gautam Borthakur, MD

Blood (2015) 126 (23): 675.

https://doi.org/10.1182/blood.V126.23.675.675

Published: 2015

Journal Articles

Phase I-II Study of Fludarabine, Cytarabine and Oxaliplatin In Patients with Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Apostolia Maria Tsimberidou, MD, PhD, Michael J Keating, MD, Elihu H. Estey, MD, Elias Jabbour, Patrick Zweidler-McKay, MD, PhD, William Plunkett, PhD, Hagop M Kantarjian, Gautam Borthakur

Blood (2011) 118 (21): 4274.

https://doi.org/10.1182/blood.V118.21.4274.4274

Published: 2011

Journal Articles

Multiple Mechanisms of Notch-Mediated B-ALL Growth Arrest Via HES1 and PLK1: KIF11, CyclinB and p53

Sankaranarayanan Kannan, PhD, Wendy Fang, MD, Patrick Zweidler-McKay, MD, PhD

Blood (2010) 116 (21): 3137.

https://doi.org/10.1182/blood.V116.21.3137.3137

Published: 2010

Journal Articles

Targeting the Leukemia-Associated Hypoxic Microenvironment with Hypoxia-Activated Prodrug PR-104

Blood (2010) 116 (21): 868.

https://doi.org/10.1182/blood.V116.21.868.868

Published: 2010

Journal Articles

Ex Vivo Expansion of Cord Blood Natural Killer Cells Overcomes Impaired Immune Synapse Formation and Effector Function in Acute Myeloid Leukemia

Dongxia Xing, PhD, Alan G Ramsay, PhD, John G. Gribben, MD, William K Decker, PhD, Jared K Burt, PhD, Sufang Li, Simon N Simon, PhD, Hong Yang, PhD, Laurence Cooper, MD, PhD, John D. McMannis, PhD, Richard E Champlin, MD, PhD, Elizabeth J Shpall, MD, Patrick Zweidler-McKay, MD, PhD, Catherine M. Bollard, MD, FRACP, FRCPA

Blood (2008) 112 (11): 2905.

https://doi.org/10.1182/blood.V112.11.2905.2905

Published: 2008

Journal Articles

Epigenetic Inactivation of Notch Signaling Target Genes HES in B Cell Acute Lymphoblastic Leukemia.

Shaoqing Kuang, Patrick Zweidler-McKay, MD, PhD, Hui Yang, Zhi Hong Fang, PhD, Weigang Tong, MD, PhD, Guillermo Garcia-Manero, MD

Blood (2008) 112 (11): 3372.

https://doi.org/10.1182/blood.V112.11.3372.3372

Published: 2008

Journal Articles

Rooting into the Soil, a Model for the Role of Sox4 in Leukemia

Saradhi Mallampati, PhD, Baohua Sun, MD, PhD, Yun Gong, MD, Enze Wang, M. James You, MD, PhD, Hesham M. Amin, MD, MSC, Yupo Ma, MD, PhD, Haifa Shen, MD, PhD, Patrick Zweidler-McKay, MD, PhD, Dan Jones, MD, PhD, Cheng Yin, Armand Glassman, MD, Hagop M. Kantarjian, MD, Ralph B. Arlinghaus, PhD, Xiaoping Sun, MD, PhD

Blood (2008) 112 (11): 3794.

https://doi.org/10.1182/blood.V112.11.3794.3794

Published: 2008

Journal Articles

A Therapeutic Approach for Acute Leukemias: Glycolysis Inhibition Revisited

Lauren J. Akers, DO, Alejandro G. Levy, MD, Anna R. Franklin, MD, Wendy Fang, MD, Peng Huang, PhD, Patrick Zweidler-McKay, MD, PhD

Blood (2008) 112 (11): 5020.

https://doi.org/10.1182/blood.V112.11.5020.5020

Published: 2008

NARROW

Mitochondrial Complex I Inhibition with Iacs-010759 in T-ALL Preclinical Models

Clinical Implementation of a Testing Algorithm for the Diagnosis of Ph-like B-Cell Acute Lymphoblastic Leukemia

Outcomes of Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia Based on Blast Genotype at Diagnosis: A Report from the Children's Oncology Group

Ex-Vivo Fucosylation Improves the Anti-Graft-Versus-Host-Disease Effects of Mesenchymal Stem Cells in the NOD/SCID/IL-2R Null Mouse Model

High-Risk Subtype of Ph-like Acute Lymphoblastic Leukemia (ALL) in Adults: Dismal Outcomes of CRLF2+ ALL Patients Treated with Intensive Chemotherapy

Targeting the NRF2/HO-1 Antioxidant Pathway with Consequences for Notch Signaling in FLT3-ITD Positive AML: A Novel Therapeutic Approach

BRD4 Proteolysis Targeting Chimera (PROTAC) Leads to Sustained Degradation of BRD4 with Broad Activity Against Acute Leukemias and Overcomes Stroma Mediated Resistance By Modulating Surface Expression of CXCR4

Phase I-II Study of Fludarabine, Cytarabine and Oxaliplatin In Patients with Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Multiple Mechanisms of Notch-Mediated B-ALL Growth Arrest Via HES1 and PLK1: KIF11, CyclinB and p53

Targeting the Leukemia-Associated Hypoxic Microenvironment with Hypoxia-Activated Prodrug PR-104

Ex Vivo Expansion of Cord Blood Natural Killer Cells Overcomes Impaired Immune Synapse Formation and Effector Function in Acute Myeloid Leukemia

Epigenetic Inactivation of Notch Signaling Target Genes HES in B Cell Acute Lymphoblastic Leukemia.

Rooting into the Soil, a Model for the Role of Sox4 in Leukemia

A Therapeutic Approach for Acute Leukemias: Glycolysis Inhibition Revisited

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American Society of Hematology

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ASH Publications

American Society of Hematology

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