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Cytokine Profile Following Varnimcabtagene Autoleucel (IMN-003A) in Patients with Relapsed Refractory B Cell Malignancies in the First-in-India Industry Phase-2 Study (IMAGINE)

Sharat Damodar, Sunil Bhat, Raja Thirumalairaj, Pankaj Malhotra, Sudeshna Dhar, Sandeepa Shetty, Mani Bharathi T.I., Anne Roshan Joseph, Gowri Shankar Krishnan, Pallavi Arasu, Sri Ramulu Elluru, Mohammed Manzoor Akheel, Rahul Nahar, Lakshmikanth Gandikota, Anil Kamat
Journal: Blood
Blood (2023) 142 (Supplement 1): 6862.
https://doi.org/10.1182/blood-2023-181585
Published: 2023
Journal Articles

Hypogammaglobulinemia and Infection Risk in Relapsed Refractory B Cell Malignancy Patients Treated with Varnimcabtagene Autoleucel (IMN-003A), a CD19-Directed Chimeric Antigen Receptor T (CAR-T) Cell Therapy, in the Phase-2 Study (IMAGINE)

Sharat Damodar, Sunil Bhat, Raja Thirumalairaj, Pankaj Malhotra, Akshatha Nayak, Pooja Mallya, Ravi Joshi, Revathy Raj, Rameez Ahamed, Charanpreet Singh, Raja B, Pallavi Arasu, Sri Ramulu Elluru, Mohammed Manzoor Akheel, Anil Kamat
Journal: Blood
Blood (2023) 142 (Supplement 1): 6853.
https://doi.org/10.1182/blood-2023-179833
Published: 2023
Journal Articles

Varnimcabtagene Autoleucel (IMN-003A): Differences in T Cell Subset Phenotype in B-ALL and B-NHL Cohorts Did Not Influence Efficacy Outcomes in the Phase-2 Study (IMAGINE)

Sunil Bhat, Sharat Damodar, Raja Thirumalairaj, Pankaj Malhotra, Alex Jose Pulikkottil, Jeetendra Kumar, Melina Soares, Sudeshna Dhar, Sandeepa Shetty, Mani Bharathi T.I., Gopinadh Jakka, Anne Roshan Joseph, Arun Kumar MG, Pallavi Arasu, Sri Ramulu Elluru, Mohammed Manzoor Akheel, Giridhar K Chenji, Lakshmikanth Gandikota, Rahul Nahar, Anil Kamat
Journal: Blood
Blood (2023) 142 (Supplement 1): 6881.
https://doi.org/10.1182/blood-2023-184521
Published: 2023
Journal Articles

Factors Associated with Refractoriness or Relapse after Varnimcabtagene Autoleucel (IMN-003A) in Patients with Relapsed Refractory B Cell Malignancies: Phase 2 First-in-India Industry (IMAGINE) Study

Sharat Damodar, Sunil Bhat, Raja Thirumalairaj, Pankaj Malhotra, Akshatha Nayak, Pooja Mallya, Ravi Joshi, Revathy Raj, Rameez Ahamed, Charanpreet Singh, Sudarshan Chougule, Deepak MB, Lakshman Vaidhyanathan, Man Updesh Singh Sachdeva, Karthik GA, Sunil HV, Jayaraj Govindaraj, Shelley Simon, Rajender Kumar Basher, Nalini Raju, Pallavi Arasu, Sri Ramulu Elluru, Mohammed Manzoor Akheel, Anil Kamat
Journal: Blood
Blood (2023) 142 (Supplement 1): 6879.
https://doi.org/10.1182/blood-2023-181112
Published: 2023
Journal Articles

Primary Analysis of Varnimcabtagene Autoleucel (IMN-003A) in Phase 2 Study (IMAGINE), a First-in-India Industry CD19-Directed CAR-T Cell Therapy for Patients with Relapsed Refractory B Cell Malignancies

Sharat Damodar, Sunil Bhat, Raja Thirumalairaj, Pankaj Malhotra, Akshatha Nayak, Pooja Mallya, Ravi Joshi, Revathy Raj, Rameez Ahamed, Charanpreet Singh, Deepak MB, Sudarshan Chougule, Lakshman Vaidhyanathan, Man Updesh Singh Sachdeva, Karthik GA, Sunil HV, Jayaraj Govindaraj, Shelley Simon, Rajender Kumar Basher, Sudeshna Dhar, Arun Kumar MG, Pallavi Arasu, Sri Ramulu Elluru, Mohammed Manzoor Akheel, Anil Kamat
Journal: Blood
Blood (2023) 142 (Supplement 1): 2104.
https://doi.org/10.1182/blood-2023-179424
Published: 2023
Journal Articles

Varnimcabtagene Autoleucel (IMN-003A): Pharmacokinetic Profile with Predominant Naïve and Central Memory Phenotype Demonstrates Sustained In Vivo Persistence and Durable Responses in a First-in-India Industry Phase-2 Study (IMAGINE)

Sunil Bhat, Sharat Damodar, Raja Thirumalairaj, Pankaj Malhotra, Pooja Mallya, Akshatha Nayak, Ravi Joshi, Revathy Raj, Charanpreet Singh, Rameez Ahamed, Sudarshan Chougule, Deepak MB, Lakshman Vaidhyanathan, Man Updesh Singh Sachdeva, Sudeshna Dhar, Anne Roshan Joseph, Arun Kumar MG, Jeetendra Kumar, Melina Soares, Rahul Nahar, Lakshmikanth Gandikota, Pallavi Arasu, Sri Ramulu Elluru, Mohammed Manzoor Akheel, Anil Kamat
Journal: Blood
Blood (2023) 142 (Supplement 1): 6876.
https://doi.org/10.1182/blood-2023-179709
Published: 2023
Journal Articles

The Bengaluru Score - a Prognostic Predictive Score for Clinical Efficacy Outcomes Based on Discovery Cohort of Patients Treated with Varnimcabtagene Autoleucel (IMN-003A) in the Phase-2 (IMAGINE) Study

Anil Kamat, Sharat Damodar, Sunil Bhat, Raja Thirumalairaj, Pankaj Malhotra, Pallavi Arasu, Mohammed Manzoor Akheel, Arun Anand
Journal: Blood
Blood (2023) 142 (Supplement 1): 6859.
https://doi.org/10.1182/blood-2023-181120
Published: 2023
Journal Articles

Reinfusion of Varnimcabtagene Autoleucel (IMN-003A) in Patients with Relapsed Refractory B Cell Malignancies Is Feasible with Sustained Responses

Sharat Damodar, Raja Thirumalairaj, Akshatha Nayak, Shilpa Prabhu, Rameez Ahamed, Deepak MB, Sudarshan Chougule, Lakshman Vaidhyanathan, Karthik GA, Sunil HV, Shelley Simon, Jayaraj Govindaraj, Pallavi Arasu, Sri Ramulu Elluru, Mohammed Manzoor Akheel, Anil Kamat
Journal: Blood
Blood (2023) 142 (Supplement 1): 6858.
https://doi.org/10.1182/blood-2023-181106
Published: 2023
Journal Articles

Modified Endothelial Activation and Stress Index (mEASIX) Score and Immune Effector Cell Associated Haematotoxicity (ICAHT) Following Varnimcabtagene Autoleucel (IMN-003A), a CD19-Directed Chimeric Antigen Receptor T (CAR-T) Cell Therapy, in the Phase-2 Study (IMAGINE)

Sunil Bhat, Sharat Damodar, Raja Thirumalairaj, Pankaj Malhotra, Pooja Mallya, Akshatha Nayak, Ravi Joshi, Revathy Raj, Charanpreet Singh, Rameez Ahamed, Manjunatha BR, Pallavi Arasu, Sri Ramulu Elluru, Mohammed Manzoor Akheel, Anil Kamat
Journal: Blood
Blood (2023) 142 (Supplement 1): 6856.
https://doi.org/10.1182/blood-2023-180478
Published: 2023
Journal Articles

Response, Peak and Persistence of Varnimcabtagene Autoleucel (IMN-003A), First-in-India Industry CD19-Directed CAR-T Cell Therapy, with Fractionated Infusions for Patients with Relapsed and/or Refractory B Cell Malignancies: Early Results (IMAGINE Study)

Sunil Bhat, Sharat Damodar, Pooja Mallya, Akshatha Nayak, Ravi Joshi, Bharath Ram S, Sudarshan Chougule, Deepak MB, Gopinadh Jakka, Sudeshna Dhar, Anne Roshan Joseph, Arun Kumar MG, Murugan Palanisamy, Jeetendra Kumar, Melina Soares, Pallavi Arasu, Sri Ramulu Elluru, Mohammed Manzoor Akheel, Anil Kamat
Journal: Blood
Blood (2022) 140 (Supplement 1): 7478–7479.
https://doi.org/10.1182/blood-2022-166650
Published: 2022