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Journal Articles

Failures and Successes in Pediatric Patients with Acute Myeloid Leukemia with First Relapse: A Large International Report on Current Treatment Strategies and Outcome

Blood (2020) 136 (Supplement 1): 6–7.

https://doi.org/10.1182/blood-2020-141774

Published: 2020

Journal Articles

Impact of Minimal Residual Disease (MRD) Assessed before Transplantation on the Outcome of Children with Acute Myeloid Leukemia Given an Allograft: A Retrospective Study By the I-BFM Study Group

Martina Pigazzi, PhD, Maddalena Benetton, Christiane Walter, MSc, Maria Hansen, Anne-Sofie Skou, MD, Ambra Da Ros, Anna Marchetti, Katia Polato, Mattia Belloni, Claudia Tregnago, PhD, Jonas Abrahamsson, MD PhD, Linda Fogelstrand, Nils Von Neuhoff, PhD, Dirk Reinhardt, MDPhD, Henrik Hasle, PhD, Franco Locatelli, MD, Pietro Merli, MD

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-137424

Published: 2020

Journal Articles

Second Relapse of Pediatric Patients with Acute Myeloid Leukemia: A Report on Current Treatment Strategies and Outcome of the AML-BFM Study Group

Mareike Rasche, MD, Emma Steidel, Martin Zimmermann, Jean-Pierre Bourquin, MD PhD, Heidrun Boztug, Iveta Janotová, Edward A. Kolb, MD, Thomas Lehrnbecher, Nils Von Neuhoff, PhD, Naghmeh Niktoreh, Nora Muehlegger, Lucie Sramkova, MD, Jan Stary, MD PhD, Christiane Walter, MSc, Ursula Creutzig, MD PhD, Michael Dworzak, MD PhD, Dirk Reinhardt, MD

Blood (2020) 136 (Supplement 1): 24.

https://doi.org/10.1182/blood-2020-139317

Published: 2020

Journal Articles

Mutational Landscape of Pediatric Acute Myeloid Leukemia: A Report of the AML-BFM Study Group with a Targeted NGS Approach in 525 Patients Integrating De Novo, Relapsed and Secondary AML

Christiane Walter, MSc, Markus Schneider, PhD, Nils Von Neuhoff, PhD, Helmut Hanenberg, MD, Dirk Reinhardt, MD, Mareike Rasche, MD

Blood (2019) 134 (Supplement_1): 1398.

https://doi.org/10.1182/blood-2019-129778

Published: 2019

Journal Articles

Impact of a Risk-Adapted Treatment Approach in Pediatric AML: A Report of the AML-BFM Registry 2012

Mareike Rasche, MD, Emma Steidel, Denise Kondryn, Nils Von Neuhoff, PhD, Lucie Sramkova, MD, Ursula Creutzig, MD, Michael Dworzak, MD, Dirk Reinhardt, MD

Blood (2019) 134 (Supplement_1): 293.

https://doi.org/10.1182/blood-2019-130969

Published: 2019

Journal Articles

Induction of a Leukemic Bone Marrow Niche Mediated By TGFB1 of Leukemic Blasts in Pediatric Acute Mekaryoblastic Leukemia: Results of an in Vitro and In Vivo Analysis

Theresa Hack, MSc, Stefanie Bertram, MD, Guntram Büsche, MD, Helmut Hanenberg, MD, Ludger Klein-Hitpass, PhD, Nils Von Neuhoff, PhD, Dirk Reinhardt, MD, Markus Schneider, PhD, Mareike Rasche, MD

Blood (2019) 134 (Supplement_1): 3734.

https://doi.org/10.1182/blood-2019-126536

Published: 2019

Journal Articles

Response to Front-Line Imatinib Treatment in Children and Adolescents with CML - Data from a Large Pediatric Cohort

Blood (2017) 130 (Supplement 1): 898.

https://doi.org/10.1182/blood.V130.Suppl_1.898.898

Published: 2017

Journal Articles

Evaluation of Genetic Mutations in Plasma Exosomes As a Biomarker Tool for Detecting the Clonal Evolution of Leukemic Cells in Pediatric AML

Fabienne Kunz, Katarina Reinhardt, PhD, Nils Von Neuhoff, PhD, Karl Welte, MD, Dirk Reinhardt, MD PhD, Basant Kumar Thakur, PhD

Blood (2016) 128 (22): 1711.

https://doi.org/10.1182/blood.V128.22.1711.1711

Published: 2016

Journal Articles

Amplicon Based Panel Targeted Resequencing Identified ZRSR2 As a Potential New Favorable Marker in Pediatric AML

Christiane Walter, MSc, Zhenyu Xu, PhD, Martin Zimmermann, PhD, Dirk Reinhardt, MD PhD, Nils Von Neuhoff, PhD

Blood (2016) 128 (22): 2905.

https://doi.org/10.1182/blood.V128.22.2905.2905

Published: 2016

Journal Articles

The Novel FLT3-N676K Mutant Induces Acute Leukemia Independently of the Inv(16) Chimeric Gene CBFB-MYH11

Kezhi Huang, Min Yang, Zengkai Pan, Florian H. Heidel, MD, Michaela Scherr, PhD, Matthias Eder, MD, Thomas Fischer, MD, Guntram Buesche, MD, Nils von Neuhoff, PhD, Arnold Ganser, MD, Zhixiong Li, MD

Blood (2015) 126 (23): 1383.

https://doi.org/10.1182/blood.V126.23.1383.1383

Published: 2015

Journal Articles

Analysis of WT1 Mutations and Combined Aberrations in Childhood Acute Myeloid Leukemia using Whole Exome Sequencing

Nils von Neuhoff, PhD, Peter Husemann, PhD, Robert Geffers, PhD, Christiane Walter, M.Sc., Christine von Neuhoff, MD, Martin Zimmermann, PhD, Brigitte Schlegelberger, MD, Dirk Reinhardt, MD PhD

Blood (2014) 124 (21): 2340.

https://doi.org/10.1182/blood.V124.21.2340.2340

Published: 2014

Journal Articles

Expression of the ETS Transcription Factor GABPα Is Correlated to BCR-ABL/ABL ratio in Human CML and Mediates Imatinib Sensitivity

Georgi Manukjan, MSc, Tim Ripperger, MDPhD, Laura Santer, BSc, Nils von Neuhoff, PhD, Arnold Ganser, MD, Axel Schambach, MDPhD, Brigitte Schlegelberger, MD, Doris Steinemann, PhD

Blood (2014) 124 (21): 1787.

https://doi.org/10.1182/blood.V124.21.1787.1787

Published: 2014

Journal Articles

Decisions Taken in Children and Adolescents with Chronic Myeloid Leukemia (CML) at Failure of Imatinib Treatment

Meinolf Suttorp, Prof. Dr., Josephine Tabea Tauer, PhD, Manuela Krumbholz, PhD, Nils von Neuhoff, PhD, Brigitte Schlegelberger, MD, Markus Metzler, Prof. Dr., Christian Thiede, MD, all Participants of Trial CML-PAED II

Blood (2014) 124 (21): 1798.

https://doi.org/10.1182/blood.V124.21.1798.1798

Published: 2014

Journal Articles

Single Cell Whole Exome Sequencing in NPM1/Flt3 Positive Pediatric Acute Myeloid Leukemia

Christiane Walter, M.Sc., Winfried Hofmann, Dr. rer. nat., Katarina Reinhardt, PhD, Dirk Reinhardt, MD PhD, Nils von Neuhoff, PhD

Blood (2014) 124 (21): 1043.

https://doi.org/10.1182/blood.V124.21.1043.1043

Published: 2014

Journal Articles

Mimicking the Bone Marrow Niche in Vitro : Establishment of a 3D Perfusion Culture System for Mesenchymal Stromal Cells

Lika Drakhlis, B.Sc., Christiane Walter, M.Sc., Maike Hinrichs, PhD, Katarina Reinhardt, PhD, Dirk Reinhardt, MD PhD, Nils von Neuhoff, PhD

Blood (2014) 124 (21): 5136.

https://doi.org/10.1182/blood.V124.21.5136.5136

Published: 2014

Journal Articles

Stability of Conversion Factors for BCR-ABL Monitoring -– Implications for the Frequency of Validation Rounds

Martin C. Müller, MD, Umang Munjal, PhD, Philipp Erben, MD, Thomas Lion, MD, PhD, Gerlinde Mitterbauer-Hohendanner, MD, Hakim El Housni, MD, Nancy Boeckx, Renata Zadro, MD, PhD, Jiri Mayer, MD, PhD, Peter Rohon, MD, Jana Rulcova, PhD, Lykke Grubach, Kadri Raudsepp, MD, Veli Kairisto, MD, PhD, Francois-Xavier Mahon, MD, PhD, Claude Preudhomme, MD, Sandrine Hayette, MD, Jean Gabert, MD, Jean-Michel Cayuela, MD, PhD, Christian Thiede, Lars Galonska, MD, Heike Pfeifer, MD, Carsten Hirt, MD, Philippe Schafhausen, MD, Nils von Neuhoff, PhD, Martin Roskos, MD, Christiane Pott, MD, Thoralf Lange, MD, Georg Hess, MD, Susanne Schnittger, PhD, Annika Dufour, MD, Steffen Koschmieder, MD, Frank Stegelmann, MD, Katerina Zoi, MD, PhD, Kostas Stamatopoulos, Hajnalka Andrikovics, MD, PhD, Tali Tohami, MD, PhD, Giovanni Martinelli, MD, Barbara Izzo, PhD, Enrico Gottardi, MD, Mindaugas Stoskus, Dag Andre Nymoen, MD, Tomasz Sacha, MD, Joana Diamond, MD, PhD, Rodica Talmaci, PhD, Andrey Misyurin, MD, Michael V. Dubina, MD, Tadej Pajic, MD, PhD, Josep F. Nomdedeu, MD, Dolors Colomer, MD, PhD, Gisela Barbany-Bustinza, MD, Hans Ehrencrona, MD, Elisabeth Oppliger Leibundgut, PhD, Jeroen Janssen, MD, Vincent H. J. van der elden, MD, Peter J.M. Valk, MD, PhD, Ugur Ozbek, MD, PhD, Lihui Wang, Gareth Gerrard, PhD, Helen E White, PhD, Thomas Schenk, MD, Thomas Ernst, MD, Rüdiger Hehlmann, MD, Giuseppe Saglio, MD, PhD, Andreas Hochhaus, MD, Nicholas C. P. Cross, PhD

Blood (2010) 116 (21): 893.

https://doi.org/10.1182/blood.V116.21.893.893

Published: 2010

Journal Articles

New Aspects for Future Stratifications In Paediatric AML: Outcome According to Cytogenetics of 386 Patients Enrolled In Study AML-BFM 2004

Christine von Neuhoff, MD, Annette Sander, MD, Jutta Bradtke, PhD, Silja Roettgers, PhD, Andrea Teigler-Schlegel, PhD, Martin Zimmermann, PhD, Johanna Ohlendorf, Nils von Neuhoff, PhD, Ursula Creutzig, MD, Dirk Reinhardt, MD, PhD

Blood (2010) 116 (21): 2741.

https://doi.org/10.1182/blood.V116.21.2741.2741

Published: 2010

Journal Articles

Proteasome Inhibitor Bortezomib Induces Apoptosis in Prednisone-Resistant Childhood Acute Lymphoblastic Leukemia Cells.

Stefanie Junk, Melchior Lauten, MD, Gunnar Cario, MD, Nicole Wittner, Martin Schrappe, MD, Brigitte Schlegelberger, MD, Nils von Neuhoff, PhD

Blood (2009) 114 (22): 991.

https://doi.org/10.1182/blood.V114.22.991.991

Published: 2009

Journal Articles

Can Bortezomib Treatment Overcome Glucocorticoid Resistance of Childhood Acute Lymphoblastic Leukemia Cells?.

Stefanie V. Junk, Melchior Lauten, MD, Gunnar Cario, MD, Nicole Wittner, Martin Schrappe, MD, Brigitte Schlegelberger, MD, Nils von Neuhoff, PhD

Blood (2007) 110 (11): 2801.

https://doi.org/10.1182/blood.V110.11.2801.2801

Published: 2007

Journal Articles

Neurotrophin Receptors and Ligands Are Highly Expressed in Acute Leukemia and Promote Leukemogenesis.

Zhixiong Li, MD, Gernot Beutel, MD, Johann Meyer, PhD, Christian Koenecke, MD, Thomas Neumann, Min Yang, Juergen Krauter, MD, Mathias Rhein, Msc, Nils von Neuhoff, PhD, Michael Heuser, MD, Helmut Diedrich, MD, Ludwig Wilkens, MD, Brigitte Schlegelberger, MD, Arnold Ganser, MD, Christopher Baum, MD

Blood (2007) 110 (11): 696.

https://doi.org/10.1182/blood.V110.11.696.696

Published: 2007

NARROW

Failures and Successes in Pediatric Patients with Acute Myeloid Leukemia with First Relapse: A Large International Report on Current Treatment Strategies and Outcome

Impact of Minimal Residual Disease (MRD) Assessed before Transplantation on the Outcome of Children with Acute Myeloid Leukemia Given an Allograft: A Retrospective Study By the I-BFM Study Group

Second Relapse of Pediatric Patients with Acute Myeloid Leukemia: A Report on Current Treatment Strategies and Outcome of the AML-BFM Study Group

Mutational Landscape of Pediatric Acute Myeloid Leukemia: A Report of the AML-BFM Study Group with a Targeted NGS Approach in 525 Patients Integrating De Novo, Relapsed and Secondary AML

Impact of a Risk-Adapted Treatment Approach in Pediatric AML: A Report of the AML-BFM Registry 2012

Induction of a Leukemic Bone Marrow Niche Mediated By TGFB1 of Leukemic Blasts in Pediatric Acute Mekaryoblastic Leukemia: Results of an in Vitro and In Vivo Analysis

Response to Front-Line Imatinib Treatment in Children and Adolescents with CML - Data from a Large Pediatric Cohort

Evaluation of Genetic Mutations in Plasma Exosomes As a Biomarker Tool for Detecting the Clonal Evolution of Leukemic Cells in Pediatric AML

Amplicon Based Panel Targeted Resequencing Identified ZRSR2 As a Potential New Favorable Marker in Pediatric AML

The Novel FLT3-N676K Mutant Induces Acute Leukemia Independently of the Inv(16) Chimeric Gene CBFB-MYH11

Analysis of WT1 Mutations and Combined Aberrations in Childhood Acute Myeloid Leukemia using Whole Exome Sequencing

Expression of the ETS Transcription Factor GABPα Is Correlated to BCR-ABL/ABL ratio in Human CML and Mediates Imatinib Sensitivity

Decisions Taken in Children and Adolescents with Chronic Myeloid Leukemia (CML) at Failure of Imatinib Treatment

Single Cell Whole Exome Sequencing in NPM1/Flt3 Positive Pediatric Acute Myeloid Leukemia

Mimicking the Bone Marrow Niche in Vitro : Establishment of a 3D Perfusion Culture System for Mesenchymal Stromal Cells

Stability of Conversion Factors for BCR-ABL Monitoring -– Implications for the Frequency of Validation Rounds

New Aspects for Future Stratifications In Paediatric AML: Outcome According to Cytogenetics of 386 Patients Enrolled In Study AML-BFM 2004

Proteasome Inhibitor Bortezomib Induces Apoptosis in Prednisone-Resistant Childhood Acute Lymphoblastic Leukemia Cells.

Can Bortezomib Treatment Overcome Glucocorticoid Resistance of Childhood Acute Lymphoblastic Leukemia Cells?.

Neurotrophin Receptors and Ligands Are Highly Expressed in Acute Leukemia and Promote Leukemogenesis.

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American Society of Hematology

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American Society of Hematology

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