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Journal Articles

VSA012, a CFB-targeted siRNA, demonstrates a favorable safety profile and sustained efficacy in PNH patients: Interim Analysis from a Phase Ib Study

Free
Neng Nie, Chen Yang, Jun Shi, WANG Shunqing, Ruiqing Zhou, Hongyan Tong, Hong Chang, Dong You, Jin Chen, Jing Hao, Bing Han
Journal: Blood
Blood (2025) 146 (Supplement 1): 381.
https://doi.org/10.1182/blood-2025-381
Published: 2025
Journal Articles

First-line romiplostim combined with immunosuppressive therapy for severe aplastic anemia: A prospective, single-arm, Phase II study

Free
Lele Zhang, Xiang Ren, Xiangrong Hu, Jing Zhang, Jianping Li, Youzhen Xiong, Neng Nie, Hong Pan, Yuan Li, Xingxin Li, Zhen Gao, Weiwang Li, Jingyu Zhao, Jinbo Huang, Xin Zhao, Guangxin Peng, Liwei Fang, Li Zhang, Yizhou Zheng, Meili Ge, Jun Shi
Journal: Blood
Blood (2025) 146 (Supplement 1): 1426.
https://doi.org/10.1182/blood-2025-1426
Published: 2025
Journal Articles

A Phase I, open-label study of CTD402, a universal CD7-targeting CAR T-cell therapy, in patients with relapsed/refractory severe aplastic anemia

Free
Lele Zhang, Ruonan Li, Jing Zhang, Jianping Li, Neng Nie, Xingxin Li, Xiao Yu, Zhexiang Kuang, Liyun Li, Jingyu Zhao, Maria del Rosario, Xiao Shi, Yong Yu, Yali Zhou, Ming Gao, Wengang Ge, Jiangtao Ren, Jan Davidson-Moncada, Jun Shi
Journal: Blood
Blood (2025) 146 (Supplement 1): 3210.
https://doi.org/10.1182/blood-2025-3210
Published: 2025
Journal Articles

Allogeneic dual-target CD19/BCMA CAR T-cell therapy (QT-019B) for refractory autoimmune hemolytic anemia

Free
Lele Zhang, Ruonan Li, Yucan Shen, Jianping Li, mengze hao, Jing Zhang, Xingxin Li, Neng Nie, Jingyu Zhao, Zhexiang Kuang, Xiao Yu, Liyun Li, Yanan Yue, Jiapan Hu, xu feng, xiaohui ding, li he, hao wang, Zhenkun wang, Hongwei Dou, xuqiang kong, Shanshan Xu, yiwen dong, Xin Zhao, yingyong xu, Luhan Yang, Jun Shi
Journal: Blood
Blood (2025) 146 (Supplement 1): 5922.
https://doi.org/10.1182/blood-2025-5922
Published: 2025
Journal Articles

Targeting CD38 with daratumumab for platelet transfusion refractoriness in aplastic anemia

Available to Purchase
Clinical Trials & Observations
Zhen Gao, Hong Pan, Lele Zhang, Weiwang Li, Ruonan Li, Jingyu Zhao, Yuechen Luo, Yu Lian, Xiao Yu, Zhexiang Kuang, Neng Nie, Jianping Li, Jinbo Huang, Xin Zhao, Yuan Li, Liwei Fang, Meili Ge, Yizhou Zheng, Jun Shi
Journal: Blood
Blood (2025) 145 (26): 3189–3193.
https://doi.org/10.1182/blood.2025029006
Published: 2025
Includes: Supplemental data
Journal Articles

Cyclophosphamide Combined with Standard Immunosuppressive Therapy Improves Early Response Outcomes in Severe Aplastic Anemia

Free
Hong Pan, Lele Zhang, Zhen Gao, Weiwang Li, Jianping Li, Neng Nie, Youzhen Xiong, Xin Zhao, Jinbo Huang, Jingyu Zhao, Xiao Yu, Zhexiang Kuang, Liwei Fang, Meili Ge, Weiping Yuan, Jun Shi
Journal: Blood
Blood (2024) 144 (Supplement 1): 5685.
https://doi.org/10.1182/blood-2024-205532
Published: 2024
Journal Articles

Daratumumab Overcome Platelet Transfusion Refractoriness in Patients with Aplastic Anemia: A Pilot Trail

Free
Zhen Gao, Hong Pan, Jinbo Huang, Xin Zhao, Lele Zhang, Weiwang Li, Jianping Li, Neng Nie, Jingyu Zhao, Liyun Li, Jing Xu, Xiao Yu, Zhexiang Kuang, Meili Ge, Liwei Fang, Jun Shi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4029.
https://doi.org/10.1182/blood-2024-204858
Published: 2024
Journal Articles

Anti-CD38 Monoclonal Antibody Is a Salvage Regimen in Relapsed/Refractory Aplastic Anemia

Free
Weiwang Li, Lele Zhang, Hong Pan, Zhen Gao, Jianping Li, Neng Nie, Xin Zhao, Jinbo Huang, Jingyu Zhao, Xiao Yu, Zhexiang Kuang, Liwei Fang, Meili Ge, Weiping Yuan, Jun Shi
Journal: Blood
Blood (2024) 144 (Supplement 1): 2697.
https://doi.org/10.1182/blood-2024-207110
Published: 2024
Journal Articles

Impaired Immunosuppressive Effect of Bone Marrow Mesenchymal Stem Cell-Derived Exosomes on T Cells in Aplastic Anemia

Free
Shichong Wang, Jiali Huo, Yilin Liu, Lingyun Chen, Xiang Ren, Xingxin Li, Min Wang, Peng Jin, Jinbo Huang, Neng Nie, Jing Zhang, Yingqi Shao, Meili Ge, Yingchang Mi, Yizhou Zheng
Journal: Blood
Blood (2023) 142 (Supplement 1): 2717.
https://doi.org/10.1182/blood-2023-178156
Published: 2023
Journal Articles

Myeloid Dendritic Cells Were Expanded and Functionally Stronger in Aplastic Anemia

Free
Lingyun Chen, Jiali Huo, Xiang Ren, Shichong Wang, Yilin Liu, Jinbo Huang, Xingxin Li, Min Wang, Peng Jin, Neng Nie, Jing Zhang, Yingqi Shao, Yingchang Mi, Yizhou Zheng, Meili Ge
Journal: Blood
Blood (2023) 142 (Supplement 1): 5657.
https://doi.org/10.1182/blood-2023-182739
Published: 2023
Journal Articles

Optimized Rabbit Antithymocyte Globulin Protocol Plus Sequential Cyclosporine and Levamisole Regimen for Newly Diagnosed Severe Aplastic Anemia: A Single-Arm, Single-Centre, Prospective, Phase 2 Trial

Free
Meili Ge, Jiali Huo, Xiang Ren, Jinbo Huang, Min Wang, Neng Nie, Jing Zhang, Peng Jin, Yingchang Mi, Yingqi Shao, Yizhou Zheng
Journal: Blood
Blood (2023) 142 (Supplement 1): 2725.
https://doi.org/10.1182/blood-2023-179386
Published: 2023
Journal Articles

Intrinsic impairment of CD4 + CD25 + regulatory T cells in acquired aplastic anemia

Free
Jun Shi, Meili Ge, Shihong Lu, Xingxin Li, Yingqi Shao, Jinbo Huang, Zhendong Huang, Jing Zhang, Neng Nie, Yizhou Zheng
Journal: Blood
Blood (2012) 120 (8): 1624–1632.
https://doi.org/10.1182/blood-2011-11-390708
Published: 2012