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Journal Articles

Rapid Personalized Manufacture (RPM) of Sleeping Beauty System-Generated NY-ESO-1-Specific TCR-T Cells Co-Expressing Membrane-Bound IL-15 Yields Anti-Tumor Responses

Lenka V Hurton, PhD, Tiejuan Mi, Kirsten C Switzer, PhD, Ling Zhang, Cuiping Dai, Misun Kim, Karishma R Bavisi, Matthew J Figliola, Vazquez M Lydia, Sourindra N Maiti, Shihuang Su, Drew C Deniger, PhD, Simon Olivares, Laurence J N Cooper, MD PhD, Harjeet Singh, MSc, PhD

Blood (2019) 134 (Supplement_1): 3218.

https://doi.org/10.1182/blood-2019-131419

Published: 2019

Journal Articles

Somatic TERT promoter Mutations in a Broad Spectrum of Telomeropathies

Fernanda Gutierrez-Rodrigues, PhD, Flávia S Donaires, PhD, André Pinto, Alana Vicente, MD, Laura Dillon, PhD, Diego V Clé, MDPhD, Bárbara Santana, Maria del Pilar Fernandez Ibanez, Danielle M. Townsley, MD MSc, Sachiko Kajigaya, PhD, Christopher S. Hourigan, DPhil FACP FRCP, James N. Cooper, MD, Rodrigo T. Calado, MD PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 539.

https://doi.org/10.1182/blood-2018-99-115430

Published: 2018

Journal Articles

Adoptive T-Cell Therapy with TCL1-Specific TCR for B-Cell Lymphomas

Jinsheng Weng, MD PhD, Kelsey Moriarty, BD, Yong Pan, Man Chun John MA, PhD, Rohit Mathur, PhD, Zheng Zhang, Hiroki Torikai, MD, Sourindra N Maiti, Fuliang Chu, PhD, Xiaoyun Cheng, Swathi Karri, Deepshika Medapalli, Laurence J N Cooper, MD PhD, R. Eric Davis, MD, Sattva S. Neelapu, MD

Blood (2018) 132 (Supplement 1): 3488.

https://doi.org/10.1182/blood-2018-99-115424

Published: 2018

Journal Articles

Eltrombopag for Refractory Severe Aplastic Anemia: Dosing Regimens, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Thomas Winkler, MD, James N. Cooper, MD, Danielle M. Townsley, MDMSc, Phillip Scheinberg, MD, Sophia Grasmeder, RN, Colin Wu, PhD, Jennifer Lotter, Marie J Desierto, MS, Ronan Desmond, MD, Matthew J. Olnes, MD PhD, Katherine R Calvo, MD PhD, Neal S. Young, MD, Cynthia E Dunbar, MD

Blood (2017) 130 (Supplement 1): 777.

https://doi.org/10.1182/blood.V130.Suppl_1.777.777

Published: 2017

Journal Articles

Myeloid Neoplasm Gene Somatic Mutations in Patients with Severe Aplastic Anemia Treated with Eltrombopag and Standard Immunosuppression

Danielle M. Townsley, MD, James N. Cooper, MD, Thomas Winkler, MD, Phillip Scheinberg, MD, Olga Rios, RN, Barbara Weinstein, RN, Janet Valdez, Jennifer Lotter, Marie J. Desierto, BS, Maria del Pilar Fernandez Ibanez, MS, Colin Wu, PhD, Cynthia E. Dunbar, MD, Wanlong Ma, BS, Maher Albitar, MD, Neal S. Young

Blood (2016) 128 (22): 727.

https://doi.org/10.1182/blood.V128.22.727.727

Published: 2016

Journal Articles

Targeting An Ancient Retrovirus In Tumor Using Engineered T Cells

Janani Krishnamurthy, Brian Rabinovich, Simon Olivares, BS, Mi Teijuan, Kirsten Switzer, Joshua Plummer, Sourindra Maiti, PHD, Harjeet Singh, PhD, Helen Huls, BS, Feng-wang Johanning, Laurence J N Cooper, MD, PhD

Blood (2013) 122 (21): 4206.

https://doi.org/10.1182/blood.V122.21.4206.4206

Published: 2013

Journal Articles

Adoptive Immunotherapy Following Umbilical Cord Blood Transplantation Using The Sleeping Beauty System and Artificial Antigen Presenting Cells To Generate Donor-Derived T Cells Expressing a CD19-Specific Chimeric Antigen Receptor

Partow Kebriaei, MD, Helen Huls, BS, Harjeet Singh, PhD, Simon Olivares, BS, Matthew Figliola, BS, Pappanaicken R Kumar, BS, Bipulendu Jena, PhD, Rineka N Jackson, BBA, Tingting Liu, BS, Ian K. McNiece, PhD, Gabriela Rondon, MD, Perry Hackett, PhD, Richard E Champlin, MD, Elizabeth J Shpall, MD, Laurence J N Cooper, MD, PhD

Blood (2013) 122 (21): 4208.

https://doi.org/10.1182/blood.V122.21.4208.4208

Published: 2013

Journal Articles

Stable Expression Of Chimeric Antigen Receptors (CARs) By Sleeping Beauty-Mediated Gene Transfer and Efficient Expansion Of Leukemia-Specific Cytokine-Induced Killer (CIK) Cells

Chiara Francesca Magnani, PhD, Nice Turazzi, Fabrizio Benedicenti, Greta Maria Paola Giordano Attianese, PhD, Sarah Tettamanti, PhD, Eugenio Montini, PhD, Laurence J N Cooper, MD, PhD, Alessandro Aiuti, MD, PhD, Andrea Biondi, MD, Ettore Biagi, MD, PhD

Blood (2013) 122 (21): 1663.

https://doi.org/10.1182/blood.V122.21.1663.1663

Published: 2013

Journal Articles

Immune Reconstitution With Activated T Cells In Companion Canines With Lymphoma

Colleen M. O'Connor, PhD, Sonny Ang, PhD, Sourindra Maiti, PHD, George McNamara, PHD, Sabina Sheppard, MS, Tasha Miller, BS, Helen Huls, BS, Richard E Champlin, MD, Heather Wilson, DVM, Laurence J N Cooper, MD, PhD

Blood (2013) 122 (21): 5153.

https://doi.org/10.1182/blood.V122.21.5153.5153

Published: 2013

Journal Articles

Ex Vivo Fucosylation Of Cord Blood Accelerates Neutrophil and Platelet Engraftment

Blood (2013) 122 (21): 691.

https://doi.org/10.1182/blood.V122.21.691.691

Published: 2013

Journal Articles

ZFN-Driven Gene Editing Prevents HLA-A Expression On Hematopoietic Stem Cells -Improving The Chance Of Finding An HLA-Matched Donor

Hiroki Torikai, Tiejuan Mi, Sonny O Ang, PhD, Loren Gragert, Martin Maiers, Sourindra Maiti, PHD, Kirsten Switzer, Helen Huls, BS, Andreas Reik, Michael C. Holmes, PhD, Philip D Gregory, PhD, Richard E Champlin, MD, Elizabeth J Shpall, MD, Laurence J N Cooper, MD, PhD

Blood (2013) 122 (21): 1655.

https://doi.org/10.1182/blood.V122.21.1655.1655

Published: 2013

Journal Articles

First Clinical Trials Employing Sleeping Beauty Gene Transfer System and Artificial Antigen Presenting Cells To Generate and Infuse T Cells Expressing CD19-Specific Chimeric Antigen Receptor

Partow Kebriaei, MD, Helen Huls, BS, Harjeet Singh, PhD, Simon Olivares, BS, Matthew Figliola, BS, Pappanaicken R. Kumar, BS, Bipulendu Jena, PhD, Marie Andree Forget, Sonny Ang, PhD, Rineka N. Jackson, BBA, Tingting Liu, BS, Doyle Bosque, ADN, Ian K. McNiece, PhD, Gabriela Rondon, MD, Perry Hackett, PhD, Chitra M. Hosing, MD, Elizabeth J. Shpall, MD, Richard E. Champlin, MD, Laurence J N. Cooper, MD, PhD

Blood (2013) 122 (21): 166.

https://doi.org/10.1182/blood.V122.21.166.166

Published: 2013

Journal Articles

Sustained Functional T Cell Persistence and B Cell Aplasia Following CD19-Targeting Adoptive T Cell Immunotherapy for Relapsed, Refractory CD19+ Malignacy

Michael Kalos, PhD, Bruce L. Levine, PhD, Timothy L Macatee, Irina Kulikovskaya, Erica Suppa, Bipulendu Jena, Saar I. Gill, MBBS, Laurence J N Cooper, MD, PhD, Stephan A. Grupp, MD, PhD, David L Porter, MD, Carl H. June, MD

Blood (2012) 120 (21): 756.

https://doi.org/10.1182/blood.V120.21.756.756

Published: 2012

Journal Articles

Targeting Leukemias by CD123 Specific Chimeric Antigen Receptor

Radhika Thokala, MS, Harjeet Singh, PhD, Simon Olivares, BS, Richard Champlin, MD, Laurence J N Cooper, MD, PhD

Blood (2011) 118 (21): 1908.

https://doi.org/10.1182/blood.V118.21.1908.1908

Published: 2011

Journal Articles

Gene Transfer to Hematopoietic Stem/Progenitor Cells As a Novel Approach for Immunotherapy Against B-Lineage Malignancies: In Vivo Xenograft Model,

Satiro N. De Oliveira, MD, Francesca Giannoni, Ph.D., Cinnamon Hardee, MS, Arineh Sahaghian, Laurence J N Cooper, MD, PhD, Donald B. Kohn, MD

Blood (2011) 118 (21): 4168.

https://doi.org/10.1182/blood.V118.21.4168.4168

Published: 2011

Journal Articles

Assessing Potential Genotoxicity of Sleeping Beauty Transposition Events in T-Cell Immunotherapy by Supercomputer-Based High Throughput Profiling,

Sonny O. Ang, PhD, Sourindra Maiti, PHD, Branden Moriarity, Martin Ossowski, PHD, Kim Andrews, PHD, Kathy Tzeng, PHD, Richard Talbot, PHD, Denise Kellar, Helen Huls, BS, Partow Kebriaei, MD, David A. Largaespada, PhD, Richard Champlin, MD, Perry Hackett, PHD, Laurence J N Cooper, MD, PhD

Blood (2011) 118 (21): 4174.

https://doi.org/10.1182/blood.V118.21.4174.4174

Published: 2011

Journal Articles

The Role of PET Scanning in Directing Immune Manipulations Following Reduced Intensity Transplants in Adults with Lymphoid Malignancies.

N. Cooper, MD, I. Avivi, MD, K. Peggs, MD, D. Hart, MD, K. Thomson, MD, A. Goldstone, MD, D. Linch, MD, P. Ell, MD, J. Bomanji, MD, S. Mackinnon, MD

Blood (2004) 104 (11): 2261.

https://doi.org/10.1182/blood.V104.11.2261.2261

Published: 2004

NARROW

Rapid Personalized Manufacture (RPM) of Sleeping Beauty System-Generated NY-ESO-1-Specific TCR-T Cells Co-Expressing Membrane-Bound IL-15 Yields Anti-Tumor Responses

Somatic TERT promoter Mutations in a Broad Spectrum of Telomeropathies

Adoptive T-Cell Therapy with TCL1-Specific TCR for B-Cell Lymphomas

Eltrombopag for Refractory Severe Aplastic Anemia: Dosing Regimens, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Myeloid Neoplasm Gene Somatic Mutations in Patients with Severe Aplastic Anemia Treated with Eltrombopag and Standard Immunosuppression

Targeting An Ancient Retrovirus In Tumor Using Engineered T Cells

Adoptive Immunotherapy Following Umbilical Cord Blood Transplantation Using The Sleeping Beauty System and Artificial Antigen Presenting Cells To Generate Donor-Derived T Cells Expressing a CD19-Specific Chimeric Antigen Receptor

Stable Expression Of Chimeric Antigen Receptors (CARs) By Sleeping Beauty-Mediated Gene Transfer and Efficient Expansion Of Leukemia-Specific Cytokine-Induced Killer (CIK) Cells

Immune Reconstitution With Activated T Cells In Companion Canines With Lymphoma

Ex Vivo Fucosylation Of Cord Blood Accelerates Neutrophil and Platelet Engraftment

ZFN-Driven Gene Editing Prevents HLA-A Expression On Hematopoietic Stem Cells -Improving The Chance Of Finding An HLA-Matched Donor

First Clinical Trials Employing Sleeping Beauty Gene Transfer System and Artificial Antigen Presenting Cells To Generate and Infuse T Cells Expressing CD19-Specific Chimeric Antigen Receptor

Sustained Functional T Cell Persistence and B Cell Aplasia Following CD19-Targeting Adoptive T Cell Immunotherapy for Relapsed, Refractory CD19+ Malignacy

Targeting Leukemias by CD123 Specific Chimeric Antigen Receptor

Gene Transfer to Hematopoietic Stem/Progenitor Cells As a Novel Approach for Immunotherapy Against B-Lineage Malignancies: In Vivo Xenograft Model,

Assessing Potential Genotoxicity of Sleeping Beauty Transposition Events in T-Cell Immunotherapy by Supercomputer-Based High Throughput Profiling,

The Role of PET Scanning in Directing Immune Manipulations Following Reduced Intensity Transplants in Adults with Lymphoid Malignancies.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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