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Journal Articles

Molecular Pathways Responsible for Adaptive Resistance to Single-Checkpoint Inhibition May Reveal Biomarkers and Immunotherapy Targets in Multiple Myeloma Patients

Barbara Castella, PhD, Myriam Foglietta, MD, Chiara Riganti, PhD, Ezio Tripoli, PharmD, Mario Boccadoro, Massimo Massaia, MD

Blood (2017) 130 (Supplement 1): 1798.

https://doi.org/10.1182/blood.V130.Suppl_1.1798.1798

Published: 2017

Journal Articles

ATP-Binding-Cassette A1 Regulates Extracellular Isopentenyl Pyrophosphate Release and Vγ9Vδ2 T-Cell Activation By Dendritic Cells

Patrizia Sciancalepore, MD, Barbara Castella, PhD, Chiara Riganti, MD, Myriam Foglietta, MD, Joanna Kopecka, PhD, Francesco Novelli, Giorgia Mandili, Ezio Tripoli, PharmD, Nico Mitro, Donatella Caruso, Mario Boccadoro, MD, Massimo Massaia, MD

Blood (2016) 128 (22): 3709.

https://doi.org/10.1182/blood.V128.22.3709.3709

Published: 2016

Journal Articles

Immune Checkpoint Blockade Combinations As Promising Strategy for Cancer Immunotherapy in Multiple Myeloma Patients

Barbara Castella, PhD, Myriam Foglietta, MD, Patrizia Sciancalepore, MD, Ezio Tripoli, PharmD, Mario Boccadoro, MD, Massimo Massaia, MD

Blood (2016) 128 (22): 2059.

https://doi.org/10.1182/blood.V128.22.2059.2059

Published: 2016

Journal Articles

Prosurvival and Chemoprotective Effects of Tumor-Associated Macrophages Reversed By Anti-CSF-1R Monoclonal Antibody in B-Cell Lymphomas

Anupama Gopisetty, PhD, Myriam Foglietta, MD PhD, Min Zhang, PhD, Zhiqiang Wang, Nathan Fowler, MD, Richard E. Davis, MD, Sattva S Neelapu, MD

Blood (2014) 124 (21): 498.

https://doi.org/10.1182/blood.V124.21.498.498

Published: 2014

Journal Articles

The Mevalonate Metabolic Pathway and the CXCL12/CXCR4 Axis Reciprocally Interact and Are Implicated in Fludarabine Resistance of Chronic Lymphocytic Leukemia Cells

Candida Vitale, MD, Valentina Griggio, MS, Chiara Riganti, MD, Ivana Campia, PhD, Marta Robino, MD, Micol Rigoni, PhD, Patrizia Sciancalepore, MD, Myriam Foglietta, MD PhD, Barbara Castella, PhD, Mario Boccadoro, MD, Massimo Massaia, Marta Coscia, MD PhD

Blood (2014) 124 (21): 833.

https://doi.org/10.1182/blood.V124.21.833.833

Published: 2014

Journal Articles

Identification of Novel Tumor-Associated Antigens in Chronic Lymphocytic Leukemia (CLL) by Serological Proteome Analysis (SERPA)

Marta Coscia, MD, PhD, Valentina Griggio, Michela Capello, PhD, Candida Vitale, MD, Federica Linty, PhD, Paola Cappello, PhD, Giorgia Mandili, PhD, Barbara Castella, PhD, Myriam Foglietta, MD, Micol Rigoni, PhD, Patrizia Sciancalepore, MD, Marta Robino, Marina Ruggeri, PhD, Daniela Drandi, PhD, Paola Omedè, PhD, Marco Ladetto, MD, Francesco Novelli, MD, Mario Boccadoro, MD, Massimo Massaia, MD

Blood (2012) 120 (21): 3878.

https://doi.org/10.1182/blood.V120.21.3878.3878

Published: 2012

Journal Articles

The Mevalonate Pathway and Downstream Signal Transducers As Therapeutic Targets to Overcome Multidrug Resistance in Chronic Lymphocytic Leukemia (CLL)

Marta Coscia, MD, PhD, Micol Rigoni, PhD, Chiara Riganti, MD, Candida Vitale, MD, Ivana Campia, PhD, Valentina Griggio, PhD, Myriam Foglietta, MD, Barbara Castella, PhD, Patrizia Sciancalepore, MD, Maria Elisa Canepari, MD, Marta Robino, Daniela Drandi, PhD, Marco Ladetto, MD, Amalia Bosia, MD, Mario Boccadoro, MD, Massimo Massaia, MD

Blood (2012) 120 (21): 3881.

https://doi.org/10.1182/blood.V120.21.3881.3881

Published: 2012

Journal Articles

PD-1 + T Cell Subsets in Follicular Lymphoma Tumor Microenvironment and Their Implications for Prognosis and Therapy

Fuliang Chu, PhD, Wencai Ma, Ph.D., Tomohide Yamazaki, Myriam Foglietta, MD, Durga Nattama, Seema Rawal, PhD, Zhiqiang Wang, Ph.D., Yanli Gao, Natalia M Orozco, Luis Vence, Laszlo Radvanyi, Chen Dong, PhD, Richard Eric Davis, MD, Sattva S. Neelapu, MD

Blood (2011) 118 (21): 2648.

https://doi.org/10.1182/blood.V118.21.2648.2648

Published: 2011

Journal Articles

Cross-Talk Between Tumor B Cells, Follicular Dendritic Cells, and Follicular Helper T Cells: Implications for Follicular Lymphoma Pathogenesis and Therapy,

Shibichakravarthy Kannan, PhD, Fuliang Chu, PhD, Seema Rawal, PhD, Myriam Foglietta, MD, David Delgado, Sattva S. Neelapu, MD

Blood (2011) 118 (21): 3696.

https://doi.org/10.1182/blood.V118.21.3696.3696

Published: 2011

Journal Articles

The Defective Proliferation of Vgamma9Vdelta2 T Cells to Zoledronic Acid In Chronic Lymphocytic Leukemia (CLL) Is a Powerful Time to First Treatment (TFT) Predictor Associated with the IGHV Mutational Status

Marta Coscia, MD, PhD, Candida Vitale, MD, Silvia Peola, PhD, Chiara Riganti, MD, Daniela Angelini, PhD, Myriam Foglietta, MD, Francesca Pantaleoni, PhD, Giorgia Matta, MD, Sabina Chiaretti, MD, Anna Guarini, PhD, Daniela Drandi, PhD, Marco Ladetto, MD, Amalia Bosia, MD, Luca Battistini, MD, Robin Foà, MD, Mario Boccadoro, MD, Jean-Jacques Fournié, PhD, Massimo Massaia, MD

Blood (2010) 116 (21): 3602.

https://doi.org/10.1182/blood.V116.21.3602.3602

Published: 2010

Journal Articles

Analysis of Antigen-Specific T-Cell Responses and Regulatory T Cells Following Sibling Donor Immunization with Patient-Derived Idiotype Vaccine Prior to Non-Myeloablative Allogeneic Stem Cell Transplantation for Multiple Myeloma.

Myriam Foglietta, MD, Sattva Neelapu, M.D., Daniel H. Fowler, Seth M. Steinberg, Larry W. Kwak, Michael R. Bishop

Blood (2009) 114 (22): 2250.

https://doi.org/10.1182/blood.V114.22.2250.2250

Published: 2009

Journal Articles

In Vitro and In Vivo Effects of CT-011, a Humanized Anti–PD-1 Monoclonal Antibody, in Combination with Rituximab against Human B-Cell Lymphomas.

Fuliang Chu, PhD, Myriam Foglietta, MD, Hong Qin, MD, PhD, Rakesh Sharma, Ph.D., Qing Yi, MD, PhD, Galina Rodionov, Rinat Rotem-Yehudar, PhD, Sattva Neelapu, M.D.

Blood (2009) 114 (22): 724.

https://doi.org/10.1182/blood.V114.22.724.724

Published: 2009

Journal Articles

CD4 + Foxp3 + Regulatory T Cells Persist in High Numbers in Peripheral Blood after Induction of Clinical Remission with Standard Chemotherapy and Suppress Tumor-Specific Effector T Cells in Patients with Follicular Lymphoma

Myriam Foglietta, MD, David Delgado, Durgha Nattamai, Larry W Kwak, MD, PhD, Sattva Neelapu, MD

Blood (2008) 112 (11): 3778.

https://doi.org/10.1182/blood.V112.11.3778.3778

Published: 2008

Journal Articles

Phenotypic and Functional Features of Vγ9/Vδ2 T Cells in Chronic Lymphocytic Leukemia Are Strongly Correlated with the Mutational Status of the Immunoglobulin Heavy Chain Variable Region (IgVH) and Metabolic Activity of the Mevalonate Pathway in Tumor Cells.

Marta Coscia, MD, Silvia Peola, PhD, Giorgia Matta, MD, Francesca Pantaleoni, PhD, Myriam Foglietta, MD, Daniela Angelini, PhD, Sabina Chiaretti, MD, Chiara Riganti, MD, Anna Guarini, PhD, Daniela Drandi, PhD, Marco Ladetto, MD, Amalia Bosia, MD, Robin Foà, MD, Luca Battistini, MD, Mario Boccadoro, MD, Jean Jacques Fournie, PhD, Massimo Massaia, MD

Blood (2007) 110 (11): 1131.

https://doi.org/10.1182/blood.V110.11.1131.1131

Published: 2007

Journal Articles

Regulatory T Cells (Tregs) Are Highly Preserved in Multiple Myeloma Patients and Can Dominate Effector Functions.

Myriam Foglietta, MD, Sara Mariani, Barbara Castella, Marta Coscia, MD, Laura Godio, MD, Serena Zappia, Mario Boccadoro, MD, Massimo Massaia, MD

Blood (2006) 108 (11): 658.

https://doi.org/10.1182/blood.V108.11.658.658

Published: 2006

NARROW

Molecular Pathways Responsible for Adaptive Resistance to Single-Checkpoint Inhibition May Reveal Biomarkers and Immunotherapy Targets in Multiple Myeloma Patients

ATP-Binding-Cassette A1 Regulates Extracellular Isopentenyl Pyrophosphate Release and Vγ9Vδ2 T-Cell Activation By Dendritic Cells

Immune Checkpoint Blockade Combinations As Promising Strategy for Cancer Immunotherapy in Multiple Myeloma Patients

Prosurvival and Chemoprotective Effects of Tumor-Associated Macrophages Reversed By Anti-CSF-1R Monoclonal Antibody in B-Cell Lymphomas

The Mevalonate Metabolic Pathway and the CXCL12/CXCR4 Axis Reciprocally Interact and Are Implicated in Fludarabine Resistance of Chronic Lymphocytic Leukemia Cells

Identification of Novel Tumor-Associated Antigens in Chronic Lymphocytic Leukemia (CLL) by Serological Proteome Analysis (SERPA)

The Mevalonate Pathway and Downstream Signal Transducers As Therapeutic Targets to Overcome Multidrug Resistance in Chronic Lymphocytic Leukemia (CLL)

PD-1 + T Cell Subsets in Follicular Lymphoma Tumor Microenvironment and Their Implications for Prognosis and Therapy

Cross-Talk Between Tumor B Cells, Follicular Dendritic Cells, and Follicular Helper T Cells: Implications for Follicular Lymphoma Pathogenesis and Therapy,

The Defective Proliferation of Vgamma9Vdelta2 T Cells to Zoledronic Acid In Chronic Lymphocytic Leukemia (CLL) Is a Powerful Time to First Treatment (TFT) Predictor Associated with the IGHV Mutational Status

Analysis of Antigen-Specific T-Cell Responses and Regulatory T Cells Following Sibling Donor Immunization with Patient-Derived Idiotype Vaccine Prior to Non-Myeloablative Allogeneic Stem Cell Transplantation for Multiple Myeloma.

In Vitro and In Vivo Effects of CT-011, a Humanized Anti–PD-1 Monoclonal Antibody, in Combination with Rituximab against Human B-Cell Lymphomas.

CD4 + Foxp3 + Regulatory T Cells Persist in High Numbers in Peripheral Blood after Induction of Clinical Remission with Standard Chemotherapy and Suppress Tumor-Specific Effector T Cells in Patients with Follicular Lymphoma

Phenotypic and Functional Features of Vγ9/Vδ2 T Cells in Chronic Lymphocytic Leukemia Are Strongly Correlated with the Mutational Status of the Immunoglobulin Heavy Chain Variable Region (IgVH) and Metabolic Activity of the Mevalonate Pathway in Tumor Cells.

Regulatory T Cells (Tregs) Are Highly Preserved in Multiple Myeloma Patients and Can Dominate Effector Functions.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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