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Meaghen Sharik
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Journal Articles

Alternate dosing schedules of BCMA-directed T cell engagers display altered pathways of relapse in syngeneic vk*MYC multiple myeloma

Free
Erin Meermeier, Caleb Stein, Meaghen Sharik, Megan Du, Yuan Zhu, Chang-Xin Shi, Kirsten Pfeffer, Keith Abayasiriwardana, Timothy Fisher, Kristin Bompiani-Myers, P. Leif Bergsagel, Marta Chesi
Journal: Blood
Blood (2025) 146 (Supplement 1): 913.
https://doi.org/10.1182/blood-2025-913
Published: 2025
Journal Articles

Preclinical evaluation of SWI/SNF targeting agents in multiple myeloma including t(4;14) subtypes

Free
Yusuke Yamashita, Jonathan Patton, Yuliza Shotts, Megan Du, Meaghen Sharik, Kirsten Pfeffer, Yuan Zhu, Chang-Xin Shi, Caleb Stein, Erin Meermeier, Marta Chesi, Lanbo Xiao, Arul Chinnaiyan, Benjamin Barwick, P. Leif Bergsagel
Journal: Blood
Blood (2025) 146 (Supplement 1): 2138.
https://doi.org/10.1182/blood-2025-2138
Published: 2025
Journal Articles

Retention of immunosuppressive C1Q macrophages following therapeutic interventions imparts negative outcomes across human multiple myeloma studies

Free
Caleb Stein, Erin Meermeier, Taxiarchis Kourelis, Joselle Cook, Yuliza Shotts, Yuan Zhu, Chang-Xin Shi, Kirsten Pfeffer, Meaghen Sharik, P. Leif Bergsagel, Marta Chesi
Journal: Blood
Blood (2025) 146 (Supplement 1): 7481.
https://doi.org/10.1182/blood-2025-7481
Published: 2025
Journal Articles

An immunostimulatory CELMoD combination overcomes resistance to T-cell engagers caused by a high multiple myeloma burden

Available to Purchase
Erin W Meermeier, Kirsten Pfeffer, Caleb K Stein, Meaghen Sharik, Megan Tien Du, Yuliza Tafoya Alvarado, Chang-Xin Shi, Yuan Xiao Zhu, Peter Leif Bergsagel, Marta Chesi
Journal: Blood
Blood blood.2025029215.
https://doi.org/10.1182/blood.2025029215
Published: 2025
Includes: Supplemental data
Journal Articles

Combination with Cytotoxic Therapy and Checkpoint Blockade Overcomes Primary Resistance to BCMA Bispecific Antibody Therapy and Leads to Durable Remission of Vk*MYC Multiple Myeloma

Free
Erin W Meermeier, Caleb K Stein, Meaghen Sharik, Megan Du, Yuan Xiao Zhu, Chang-Xin Shi, Yuliza Shotts, Maria Josic, Keith Abayasiriwardana, Natalie Bezman, Timothy Fisher, Kristin Bompiani-Myers, Leif Bergsagel, Marta Chesi
Journal: Blood
Blood (2024) 144 (Supplement 1): 358.
https://doi.org/10.1182/blood-2024-210917
Published: 2024
Journal Articles

Celmod-Dexamethasone Combination Overcomes Primary Resistance to T Cell Engagers Caused By High Tumor Burden in a Human CRBN + Preclinical Model of Multiple Myeloma

Free
Erin W Meermeier, Meaghen Sharik, Megan Du, Caleb K Stein, Yuan Xiao Zhu, Chang-Xin Shi, Yuliza Shotts, Leif Bergsagel, Marta Chesi
Journal: Blood
Blood (2024) 144 (Supplement 1): 356.
https://doi.org/10.1182/blood-2024-212225
Published: 2024
Journal Articles

Abundance of C1q Expressing Macrophages Promotes Resistance to Modern Therapy

Free
Caleb K Stein, Erin W Meermeier, Yuliza Shotts, Yuan Xiao Zhu, Chang-Xin Shi, Kirsten Pfeffer, Megan Du, Meaghen Sharik, Leif Bergsagel, Marta Chesi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3275.
https://doi.org/10.1182/blood-2024-212331
Published: 2024