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Matthew Vander Heiden, MD PhD
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Journal Articles

DHODH Inhibitors in the Treatment of Acute Myeloid Leukemia: Defining the Mechanism of Action and the Basis of the Metabolic Therapeutic Window

Peggy P. Hsu, MD PhD, Youmna Kfoury, PhD, Najihah Aziz, Jenna Elkhoury, Brittany Hallgren, David T. Scadden, MD, Matthew Vander Heiden, MD PhD, David B Sykes, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2716.
https://doi.org/10.1182/blood-2018-99-113387
Published: 2018
Journal Articles

Aldehyde Dehydrogenase 3a2 (Aldh3a2) Represents a Distinct Metabolic Vulnerability in MLL-AF9 AML Leukemia Initiating Cells

Rushdia Z. Yusuf, MBBS, MPH, Sanket S. Acharya, BA, MBS, Vionnie W.C. Yu, PhD, Borja Saez, PhD, Julien M Cobert, BA, John Doench, PhD, Lars Bullinger, MD, PhD, Dana S'aulis, BA, Dongjun Lee, PhD, Rahul Palchaudhuri, PhD, Akachimere C. Uzosike, Mildred Duvet, BA, David J. Logan, PhD, Sudeshna Das, PhD, Colleen M Cook, BA, Michael Churchill, BS, Elizabeth Scadden, BA, Gohar Warraich, Hao Liu, BA, Shrikanta Chattopadhyay, MD, Adam Brown, PhD, Stephen M. Sykes, PhD, David B. Sykes, MD, PhD, Francois Mercier, MD, Anne E. Carpenter, PhD, Scott A. Armstrong, MD, PhD, Matthew Vander Heiden, MD, PhD, Benjamin L. Ebert, Andrew L. Kung, MD, PhD, William B. Rizzo, MD, Siddhartha Mukherjee, MD, PhD, David T. Scadden, MD
Journal: Blood
Blood (2012) 120 (21): 208.
https://doi.org/10.1182/blood.V120.21.208.208
Published: 2012
Journal Articles

Cellular Bioenergetics in Lymphoid Neoplasia

Matthew Vander Heiden, MD, PhD
Journal: Blood
Blood (2011) 118 (21): SCI-25.
https://doi.org/10.1182/blood.V118.21.SCI-25.SCI-25
Published: 2011
Journal Articles

Metabolism-Induced Reactive Oxygen Species and Hif1α-Mediated Gene Regulation Control the Timing and Magnitude of Hematopoietic Stem Cell Induction

James M Harris, Lauren J. Harris, Andrew G Cox, Maija K Garnaas, Gregory M Frechette, Mauricio Cortes, Claire C Cutting, Michael C Dovey, PhD, Barry H. Paw, M.D., Ph.D., Matthew Vander Heiden, MD, PhD, Wolfram Goessling, MD, PhD, Trista E. North, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 1266.
https://doi.org/10.1182/blood.V118.21.1266.1266
Published: 2011
Journal Articles

Leukemogenic Tyrosine Kinases Inhibit PKM2 to Promote the Warburg Effect and Tumor Growth

Taro Hitosugi, PhD, Sumin Kang, PhD, Matthew Vander Heiden, MD/PhD, Tea-wook Chung, PhD, Shannon Elf, Katherine Lythgoe, Shaozhong Dong, PhD, Sagar Lonial, MD, Xu Wang, PhD, Georgia Chen, PhD, Jianxin Xie, PhD, Ting-Lei Gu, PhD, Roberto Polakiewicz, PhD, Johannes L. Roesel, PhD, Titus Boggon, PhD, Fadlo Khuri, MD, D. Gary Gilliland, MD, PhD, Lewis Cantley, PhD, Jonathan L. Kaufman, MD, Jing Chen, PhD
Journal: Blood
Blood (2010) 116 (21): 3142.
https://doi.org/10.1182/blood.V116.21.3142.3142
Published: 2010