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Margrét Sigurdardóttir
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Journal Articles

Approaching Hypercalcemia in Monoclonal Gammopathy of Undetermined Significance: Insights from the iStopMM study

Ástrún Helga Jónsdóttir, Helga Ágústa Sigurjónsdóttir, Prof., Sigrun Thorsteinsdottir, Thorir Einarsson Long, Ingigerður Sólveig Sverrisdóttir, Elias Eythorsson, Jon Thorir Oskarsson, Runólfur Pálsson, Olafur Skuli Indridason, Bryjnar Vidarsson, Pall T Onundarson, Isleifur Olafsson, Ingunn Þorsteinsdóttir, Bjarni A Agnarsson, Margret Sigurdardottir, Asbjorn Jonsson, Malin L. Hultcrantz, Brian G.M. Durie, Stephen Harding, Carl Ola Landgren, Thorvardur Jon Love, Sigurdur Yngvi Kristinsson, Sæmundur Rögnvaldsson
Journal: Blood
Blood blood.2024025624.
https://doi.org/10.1182/blood.2024025624
Published: 2024
Includes: Supplemental data
Journal Articles

Differential Detection of Clonal Bone Marrow Plasma Cells in IgA Vs. IgG Monoclonal Gammopathy of Undetermined Significance and Its Association with Disease Progression

Jon Thorir Oskarsson, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Andri Olafsson, Elias Eythorsson, Asbjorn Jonsson, Brynjar Vidarsson, Pall T. Onundarson, Bjarni Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Isleifur Olafsson, Stephen J. Harding, Brian G.M. Durie, Thorvardur Jon Love, Sigurdur Y Kristinsson
Journal: Blood
Blood (2024) 144 (Supplement 1): 1015.
https://doi.org/10.1182/blood-2024-200422
Published: 2024
Journal Articles

Predicting an Underlying Clonal Plasma Cell Population in Light-Chain Monoclonal Gammopathy of Undetermined Significance Using Free Light-Chain Ratio

Jon Thorir Oskarsson, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Thorir E. Long, Gudrun Asta Sigurdardottir, Asdis Rosa Thordardottir, Gauti Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Elias Eythorsson, Asbjorn Jonsson, Brynjar Vidarsson, Pall T. Onundarson, Bjarni Agnarsson, Robert Palmason, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Isleifur Olafsson, Stephen J. Harding, Brian GM Durie, Thorvardur Jon Love, Sigurdur Y. Kristinsson
Journal: Blood
Blood (2023) 142 (Supplement 1): 530.
https://doi.org/10.1182/blood-2023-182661
Published: 2023
Journal Articles

Risk Factors of Smoldering Multiple Myeloma: Results from the Screened Istopmm Study

Sigrun Thorsteinsdottir, Ingigerdur Sverrisdottir, Sæmundur Rögnvaldsson, Sara Ekberg, Malin Hultcrantz, Brynjar Vidarsson, Pall T. Onundarson, Bjarni Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Isleifur Olafsson, Asdis Rosa Thordardottir, Jon Thorir Oskarsson, Gudrun Asta Sigurdardottir, Elias Eythorsson, Asbjorn Jonsson, Gauti Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Thorir Einarsson Long, Brian GM Durie, Stephen J. Harding, Ola Landgren, Thorvardur Jon Love, Sigurdur Y. Kristinsson
Journal: Blood
Blood (2023) 142 (Supplement 1): 3397.
https://doi.org/10.1182/blood-2023-188469
Published: 2023
Journal Articles

The Early Benefits and Psychological Effects of Screening for Monoclonal Gammopathy of Undetermined Significance: Results of the Istopmm Study

Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Jon Oskarsson, Elias Eythorsson, Gudrun Asta Sigurdardottir, Brynjar Vidarsson, Pall T. Onundarson, Bjarni Agnarsson, Margret Sigurdardottir, Isleifur Olafsson, Ingunn Thorsteinsdottir, Andri Steinthor Bjornsson, Inga Dröfn Wessman, Gauti Gislason, Jon Kristinn Sigurdsson, Andri Olafsson, Ingigerdur Sverrisdottir, Thorir E. Long, Robert Palmason, Signy Vala Sveinsdottir, Fridbjorn Sigurdsson, Asdis Rosa Thordardottir, Asbjorn Jonsson, Runolfur Palsson, Olafur Indridason, Elin Ruth Reed, Gudlaug Katrin Hakonardottir, Hlif Steingrimsdottir, Malin Hultcrantz, Brian GM Durie, Stephen J. Harding, Thor Aspelund, Ola Landgren, Thorvardur Jon Love, Sigurdur Y. Kristinsson
Journal: Blood
Blood (2023) 142 (Supplement 1): 214.
https://doi.org/10.1182/blood-2023-186397
Published: 2023
Journal Articles

Monoclonal Gammopathy of Undetermined Significance and the Risk of Thrombotic Events: Results from Istopmm, a Population-Based Screening Study in Iceland

Sæmundur Rögnvaldsson, Alessandro Gasparini, Sigrun Thorsteinsdottir, Ingigerdur Sverrisdottir, Elias Eythorsson, Thorir E. Long, Brynjar Vidarsson, Pall T. Onundarson, Bjarni Agnarsson, Margret Sigurdardottir, Isleifur Olafsson, Ingunn Thorsteinsdottir, Jon Oskarsson, Robert Palmason, Signy Vala Sveinsdottir, Asdis Rosa Thordardottir, Asbjorn Jonsson, Runolfur Palsson, Olafur Indridason, Thor Aspelund, Gauti Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Malin Hultcrantz, Brian GM Durie, Stephen J. Harding, Ola Landgren, Thorvardur Jon Love, Sigurdur Y. Kristinsson
Journal: Blood
Blood (2023) 142 (Supplement 1): 216.
https://doi.org/10.1182/blood-2023-186098
Published: 2023
Journal Articles

Sars-Cov-2 Infection Does Not Lead to Progression of Monoclonal Gammopathy of Undetermined Significance: Results from the Population-Based Istopmm Screening Study

Robert Palmason, Sara Ekberg, Elias Eythorsson, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Michael Crowther, Elin Ruth Reed, Jon Oskarsson, Gudrun Asta Sigurdardottir, Thor Aspelund, Brynjar Vidarsson, Pall T. Onundarson, Bjarni Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Signy Vala Sveinsdottir, Isleifur Olafsson, Asdis Rosa Thordardottir, Asbjorn Jonsson, Olafur Indridason, Gauti Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Hlif Steingrimsdottir, Thorir E. Long, Malin Hultcrantz, Brian GM Durie, Stephen J. Harding, Ola Landgren, Runolfur Palsson, Thorvardur Jon Love, Sigurdur Y. Kristinsson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4766.
https://doi.org/10.1182/blood-2023-173078
Published: 2023
Journal Articles

Revised Definition of Free Light Chains in Serum and Light Chain Monoclonal Gammopathy of Undetermined Significance: Results of the Istopmm Study

Thorir Einarsson Long, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Ingigerdur Sverrisdottir, Elias Eythorsson, Olafur Indridason, Runolfur Palsson, Thor Aspelund, Brynjar Vidarsson, Pall T. Onundarson, Bjarni Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Isleifur Olafsson, Asdis Rosa Thordardottir, Asbjorn Jonsson, Gauti Gislason, Andri Olafsson, Malin Hultcrantz, Brian GM Durie, Stephen J. Harding, Thorvardur Jon Love, Ola Landgren, Sigurdur Y. Kristinsson
Journal: Blood
Blood (2023) 142 (Supplement 1): 535.
https://doi.org/10.1182/blood-2023-188547
Published: 2023
Journal Articles

Transient M-Proteins: Epidemiology, Causes, and the Impact of Mass Spectrometry: The Istopmm Study

Robert Palmason, Oscar Berlanga, Jon Kristinn Sigurdsson, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Sara Ekberg, Michael Crowther, Marina Levy, Elin Ruth Reed, Jon Þórir Oskarsson, Gudrun Asta Sigurdardottir, Brynjar Vidarsson, Pall Torfi Onundarson, Bjarni Agnar Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Signy Vala Sveinsdottir, Fridbjorn Sigurdsson, Isleifur Olafsson, Asdis Rosa Thordardottir, Elias Eythorsson, Asbjorn Jonsson, Runolfur Palsson, Olafur Skuli Indridason, Thor Aspelund, Gauti Gislason, Andri Olafsson, Ingigerdur Solveig Sverrisdottir, Hlif Steingrimsdottir, Thorir Einarsson Long, Malin Hultcrantz, Ola Landgren, Stephen Harding, Brian G.M. Durie, Thorvardur Jon Love, Sigurdur Y Kristinsson
Journal: Blood
Blood (2022) 140 (Supplement 1): 2338–2340.
https://doi.org/10.1182/blood-2022-164758
Published: 2022
Journal Articles

Sars-Cov-2 Vaccinations Do Not Lead to Progression of Monoclonal Gammopathy of Undetermined Significance: Results from the Population-Based Istopmm Screening Study

Robert Palmason, Elias Eythorsson, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Sara Ekberg, Michael Crowther, Elin Ruth Reed, Jon Þórir Oskarsson, Gudrun Asta Sigurdardottir, Thor Aspelund, Brynjar Vidarsson, Pall Torfi Onundarson, Bjarni Agnar Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Signy Vala Sveinsdottir, Isleifur Olafsson, Asdis Rosa Thordardottir, Asbjorn Jonsson, Olafur Skuli Indridason, Gauti Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Hlif Steingrimsdottir, Thorir Einarsson Long, Malin Hultcrantz, Brian G.M. Durie, Stephen Harding, Ola Landgren, Runolfur Palsson, Thorvardur Jon Love, Sigurdur Y Kristinsson
Journal: Blood
Blood (2022) 140 (Supplement 1): 261–263.
https://doi.org/10.1182/blood-2022-157138
Published: 2022
Journal Articles

Circulating Tumor Plasma Cells in the Screened Istopmm Smoldering Multiple Myeloma Cohort

Sigrún Thorsteinsdóttir, Jon Þórir Oskarsson, Sæmundur Rögnvaldsson, Gauti Gíslason, Thor Aspelund, Gudrún Ásta Sigurdardóttir, Ásdis Rósa Thórdardottir, Brynjar Vidarsson, Páll Torfi Onundarson, Bjarni Agnar Agnarsson, Margrét Sigurdardóttir, Ingunn Thorsteinsdóttir, Ísleifur Ólafsson, Elias Eythorsson, Ásbjorn Jónsson, Malin Hultcrantz, Ola Landgren, Stephen Harding, Brian G.M. Durie, Thorvardur Jon Love, Sigurdur Y Kristinsson
Journal: Blood
Blood (2022) 140 (Supplement 1): 9923–9924.
https://doi.org/10.1182/blood-2022-168690
Published: 2022
Journal Articles

Prevalence of MGUS Is High in the Istopmm Study but the Prevalence of IgA MGUS Does Not Increase with Age in the Way Other Immunoglobulin Subtypes Do

Thorvardur Jon Love, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Thor Aspelund, Elin Ruth Reed, Brynjar Vidarsson, Pall Torfi Onundarson, Bjarni Agnar Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Signy Vala Sveinsdottir, Isleifur Olafsson, Fridbjorn Sigurdsson, Asdis Rosa Thordardottir, Elias Eythorsson, Asbjorn Jonsson, Runolfur Palsson, Olafur Skuli Indridason, Gauti Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Ingigerdur Solveig Sverrisdottir, Hlif Steingrimsdottir, Thorir Einarsson Long, Malin Hultcrantz, Brian G.M. Durie, Stephen Harding, Ola Landgren, Sigurdur Y Kristinsson
Journal: Blood
Blood (2022) 140 (Supplement 1): 256–258.
https://doi.org/10.1182/blood-2022-163169
Published: 2022
Journal Articles

Predicting the Need for Upfront Bone Marrow Sampling in Individuals with MGUS: Derivation of a Multivariable Prediction Model Using the Prospective Population-Based Istopmm Cohort

Elias Eythorsson, Sæmundur Rögnvaldsson, Sigrún Thorsteinsdóttir, Elin Ruth Reed, Gudrún Ásta Sigurdardóttir, Brynjar Vidarsson, Páll Torfi Onundarson, Bjarni Agnarsson, Margrét Sigurdardóttir, Ísleifur Ólafsson, Ingunn Þorsteinsdóttir, Signy Vala Sveinsdottir, Fridbjorn Sigurdsson, Ásdis Rósa Thórdardottir, Runolfur Palsson, Olafur Indridason, Thorir Einarsson Long, Asbjorn Jonsson, Gauti Kjartan Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Hlif Steingrimsdottir, Malin Hultcrantz, Brian G.M. Durie, Stephen Harding, Ola Landgren, Thor Aspelund, Thorvardur Jon Love, Sigurdur Y Kristinsson
Journal: Blood
Blood (2022) 140 (Supplement 1): 266–267.
https://doi.org/10.1182/blood-2022-170166
Published: 2022
Journal Articles

Monoclonal Gammopathy of Undetermined Significance and Risk of Chronic Kidney Disease: Results of the Population-Based Iceland Screens, Treats, or Prevents Multiple Myeloma (iStopMM) Study

Thorir Einarsson Long, Elias Eythorsson, Sæmundur Rögnvaldsson, Olafur Indridason, Runolfur Palsson, Sigrún Thorsteinsdóttir, Ingigerdur S Sverrisdottir, Thor Aspelund, Brynjar Vidarsson, Páll Torfi Onundarson, Bjarni Agnarsson, Margrét Sigurdardóttir, Ingunn Thorsteinsdottir, Ísleifur Ólafsson, Asdis Rosa Thordardottir, Asbjorn Jonsson, Gauti Kjartan Gislason, Andri Olafsson, Hlif Steingrimsdottir, Malin Hultcrantz, Brian G.M. Durie, Stephen Harding, Ola Landgren, Thorvardur Jon Love, Sigurdur Y Kristinsson
Journal: Blood
Blood (2022) 140 (Supplement 1): 10108–10109.
https://doi.org/10.1182/blood-2022-170623
Published: 2022
Journal Articles

Autoimmune Diseases Are Not Associated with Monoclonal Gammopathy of Undetermined Significance: Results of the Prospective Population-Based Istopmm Study

Ingigerdur S Sverrisdottir, Sigrún Thorsteinsdóttir, Sæmundur Rögnvaldsson, Thor Aspelund, Brynjar Vidarsson, Páll Torfi Önundarson, Bjarni Agnarsson, Margrét Sigurdardóttir, Ingunn Thorsteinsdottir, Signy Vala Sveinsdottir, Robert Palmason, Ísleifur Ólafsson, Fridbjorn Sigurdsson, Ásdis Rósa Thórdardottir, Elias Eythorsson, Asbjorn Jonsson, Runolfur Palsson, Olafur Skuli Indridason, Gauti Kjartan Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Hlif Steingrimsdottir, Thorir Einarsson Long, Malin Hultcrantz, Brian G.M. Durie, Stephen Harding, Ola Landgren, Sigurdur Y Kristinsson, Thorvardur Jon Love
Journal: Blood
Blood (2022) 140 (Supplement 1): 10031–10032.
https://doi.org/10.1182/blood-2022-169393
Published: 2022
Journal Articles

Monoclonal Gammopathy of Undetermined Significance (MGUS) with Multiple Paraproteins: Results from the Population-Based Istopmm Screening Study

Sæmundur Rögnvaldsson, Jon Þórir Oskarsson, Sigrun Thorsteinsdottir, Elin Ruth Reed, Gudrun Asta Sigurdardottir, Brynjar Vidarsson, Pall Torfi Onundarson, Margret Sigurdardottir, Bjarni Agnar Agnarsson, Isleifur Olafsson, Ingunn Thorsteinsdottir, Signy Vala Sveinsdottir, Robert Palmason, Fridbjorn Sigurdsson, Asdis Rosa Thordardottir, Elias Eythorsson, Asbjorn Jonsson, Runolfur Palsson, Olafur Skuli Indridason, Thor Aspelund, Gauti Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Ingigerdur S Sverrisdottir, Gudlaug Katrin Hakonardottir, Thorir Einarsson Long, Ragnar Danielsen, Malin Hultcrantz, Brian G.M. Durie, Stephen Harding, Ola Landgren, Thorvardur Jon Love, Sigurdur Y Kristinsson
Journal: Blood
Blood (2022) 140 (Supplement 1): 10024–10026.
https://doi.org/10.1182/blood-2022-168070
Published: 2022
Journal Articles

Determining Hemodilution in Diagnostic Bone Marrow Samples in Multiple Myeloma and Its Precursors By Next-Generation Flow Cytometry: Data from the Iceland Screens, Treats, or Prevents Multiple Myeloma (iStopMM) Study

Jón Þórir Óskarsson, Sæmundur Rögnvaldsson, Sigrún Thorsteinsdóttir, Hrafnhildur Una þórðardóttir, Gudlaug Katrin Hakonardottir, Steinar Bragi Gunnarsson, Gudrún Ásta Sigurdardóttir, Ásdis Rósa Thórdardottir, Gauti Gíslason, Andri Olafsson, Jon Kristinn Sigurdsson, Brynjar Vidarsson, Páll Torfi Onundarson, Bjarni Agnar Agnarsson, Robert Palmason, Margrét Sigurdardóttir, Ingunn Thorsteinsdóttir, Ísleifur Ólafsson, Juan Flores-Montero, Alberto Orfao, Brian G.M. Durie, Thorvardur Jon Love, Sigurdur Y Kristinsson
Journal: Blood
Blood (2022) 140 (Supplement 1): 7166–7167.
https://doi.org/10.1182/blood-2022-168741
Published: 2022
Journal Articles

Hypercalcemia in Individuals with Monoclonal Gammopathy of Undetermined Significance: Results from the Istopmm Study

Ástrún Helga Jónsdóttir, Sæmundur Rögnvaldsson, Helga Ágústa Sigurjónsdóttir, Sigrún Thorsteinsdóttir, Brynjar Vidarsson, Páll Torfi Onundarson, Bjarni Agnarsson, Margrét Sigurdardóttir, Ingunn Thorsteinsdóttir, Ísleifur Ólafsson, Signy Vala Sveinsdottir, Robert Palmason, Ásdis Rósa Thórdardottir, Elias Eythorsson, Asbjorn Jonsson, Runolfur Palsson, Olafur Skuli Indridason, Gauti Kjartan Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Ingigerdur S Sverrisdottir, Thorir Einarsson Long, Thor Aspelund, Malin Hultcrantz, Brian G.M. Durie, Stephen Harding, Ola Landgren, Thorvardur Jon Love, Sigurdur Y Kristinsson
Journal: Blood
Blood (2022) 140 (Supplement 1): 10099–10100.
https://doi.org/10.1182/blood-2022-168822
Published: 2022
Journal Articles

Defining New Reference Intervals for Serum Free Light Chains in Individuals with Reduced Kidney Function: Results of the Population- Based on Iceland Screens Treats or Prevents Multiple Myeloma (iStopMM) Study

Thorir Einarsson Long, Olafur Skuli Indridason, Runolfur Palsson, Sæmundur Rögnvaldsson, Thorvardur Jon Love, Sigrun Thorsteinsdottir, Ingigerdur Solveig Sverrisdottir, Brynjar Vidarsson, Pall Torfi Onundarson, Bjarni Agnar Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Isleifur Olafsson, Asdis Rosa Thordardottir, Elias Eythorsson, Asbjorn Jonsson, Gauti Gislason, Andri Olafsson, Hlif Steingrimsdottir, Petros Kampanis, Malin Hultcrantz, Brian G.M. Durie, Stephen Harding, Ola Landgren, Sigurdur Yngvi Kristinsson
Journal: Blood
Blood (2021) 138 (Supplement 1): 542.
https://doi.org/10.1182/blood-2021-153827
Published: 2021
Journal Articles

Monitoring of Circulating Tumor Plasma Cells in Patients with Precursor Conditions of Multiple Myeloma: Data from the Prospective Iceland Screens, Treats, or Prevents Multiple Myeloma (iStopMM) Study

Jón Þórir Óskarsson, Iris Petursdottir, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Gudrun Asta Sigurdardottir, Asdis Rosa Thordardottir, Gauti Kjartan Gislason, Andri Olafsson, Brynjar Vidarsson, Pall Torfi Onundarson, Bjarni Agnar Agnarsson, Robert Palmason, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Isleifur Olafsson, Brian G.M. Durie, Thorvardur Jon Love, Sigurdur Y Kristinsson
Journal: Blood
Blood (2021) 138 (Supplement 1): 2645.
https://doi.org/10.1182/blood-2021-146363
Published: 2021