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Marcos J. Ruiz
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Journal Articles

Bone Marrow Stromal Cells Enhance DNA Damage Signaling Independent Of Stat3 Activation In Pediatric AML

Xin Long, PhD, Marcos J. Ruiz, BS, Michele S. Redell, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2548.
https://doi.org/10.1182/blood.V122.21.2548.2548
Published: 2013
Journal Articles

FACS analysis of Stat3/5 signaling reveals sensitivity to G-CSF and IL-6 as a significant prognostic factor in pediatric AML: a Children's Oncology Group report

Clinical Trials & Observations
Michele S. Redell, Marcos J. Ruiz, Robert B. Gerbing, Todd A. Alonzo, Beverly J. Lange, David J. Tweardy, Soheil Meshinchi
Journal: Blood
Blood (2013) 121 (7): 1083–1093.
https://doi.org/10.1182/blood-2012-04-421925
Published: 2013
Includes: Supplemental data
Journal Articles

Increased Responsiveness to Ligand Stimulation of the STAT Pathway At Relapse in Acute Myelogenous Leukemia

Alexandra M. Stevens, MD, Marcos J. Ruiz, BS, Michele S. Redell, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3544.
https://doi.org/10.1182/blood.V120.21.3544.3544
Published: 2012
Journal Articles

FACS Analysis of Stat3/5 Signaling Reveals Ligand Sensitivity As a Significant Prognostic Factor in Pediatric AML: A Children's Oncology Group Report

Michele S. Redell, MD, PhD, Marcos J. Ruiz, BS, Robert B. Gerbing, M.A., Todd A. Alonzo, PhD, Beverly Lange, MD, David J. Tweardy, MD, Soheil Meshinchi, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 938.
https://doi.org/10.1182/blood.V118.21.938.938
Published: 2011
Journal Articles

Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor

Michele S. Redell, Marcos J. Ruiz, Todd A. Alonzo, Robert B. Gerbing, David J. Tweardy
Journal: Blood
Blood (2011) 117 (21): 5701–5709.
https://doi.org/10.1182/blood-2010-04-280123
Published: 2011
Includes: Supplemental data
Journal Articles

Multiparameter FACS Analysis of G-CSF and IL-6 Signaling through Stat3 and Stat5 In Primary Pediatric AML Samples.

Michele S. Redell, MD, PhD, Marcos J. Ruiz, BS, Robert B. Gerbing, Todd A. Alonzo, PhD, David John Tweardy, MD
Journal: Blood
Blood (2010) 116 (21): 1051.
https://doi.org/10.1182/blood.V116.21.1051.1051
Published: 2010
Journal Articles

3-D Pharmacophore Identification of Second Generation Small Molecule Inhibitors of Stat3 SH2-Phosphotyrosine Binding That Induce Apoptosis in Acute Myeloid Leukemia Cells.

Redell S. Redell, MD, PhD, Xuejun Xu, PhD, Moses M. Kasembeli, PhD, Marcos J. Ruiz, David John Tweardy, MD
Journal: Blood
Blood (2009) 114 (22): 1727.
https://doi.org/10.1182/blood.V114.22.1727.1727
Published: 2009
Journal Articles

Stat3β Promotes Basal Granulopoiesis and Inhibits Emergency Granulopoiesis, While Stat3α Inhibits Basal Granulopoiesis and Promotes Emergency Granulopoiesis

Michele Redell, MD, PhD, S. Wen-Wen Chen, MD, Marcos J. Ruiz, David J. Tweardy, MD
Journal: Blood
Blood (2008) 112 (11): 3871.
https://doi.org/10.1182/blood.V112.11.3871.3871
Published: 2008
Journal Articles

Wild-Type and Mutant C-Kit Activation of Stat3α Contribute to Leukemogenesis through Distinct Effects on Myeloid Cell Proliferation and Resistance to Apoptosis

Michele Redell, MD, PhD, Marcos J. Ruiz, David John Tweardy, MD
Journal: Blood
Blood (2008) 112 (11): 5317.
https://doi.org/10.1182/blood.V112.11.5317.5317
Published: 2008