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Malith Karunasiri
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Journal Articles

Epithelial growth factor like-7 (EGFL7) regulates hematopoiesis stem cell (HSC) activation via AP-1 suppression

Free
Rohan Kulkarni, Yaphet Bustos, Alexander Rudich, Malith Karunasiri, Amog Urs, Ozlen Balcioglu, Wenjun Li, Sadie Chidester, Kyleigh Rodgers, Elizabeth Garfinkle, Ami Patel, Katherine Miller, Phillip Popovich, Shannon Elf, Ramiro Garzon, Chinmayee Goda, Adrienne Dorrance
Journal: Blood
Blood (2025) 146 (Supplement 1): 209.
https://doi.org/10.1182/blood-2025-209
Published: 2025
Journal Articles

BET inhibition targets pathogenic interstitial macrophages to limit antibody mediated fibrosis in bronchiolitis obliterans chronic gvhd

Free
Rathan Kumar, Lotus Neidemire-Colley, Elizabeth Garfinkle, Camryn Steere, Simran Surana, Annie Murray, Giorgia Giordano, Olivia Martin, Emerson Woodbury, Kara Corps, Malith Karunasiri, Mathew Gorr, Loren Wold, Kenneth Oestreich, Nicole Grieselhuber, Bruce Blazar, Ivan Maillard, Katherine Miller, Hannah Choe, Parvarthi Ranganathan
Journal: Blood
Blood (2025) 146 (Supplement 1): 5859.
https://doi.org/10.1182/blood-2025-5859
Published: 2025
Journal Articles

Disrupted DNA repair and oxidative stress responses underlie hematopoietic stem cell failure after spinal cord injury

Free
Kyleigh Rodgers, Katherine Mifflin, Kristina Kigerl, Jodie Hall, Rohan Kulkarni, Elizabeth Garfinkle, Elham Asghari, Cankun Wang, Wenmin Lai, Zhen Guan, Malith Karunasiri, Chinmayee Goda, Katherine Miller, Qin Ma, Adrienne Dorrance, Phillip Popovich
Journal: Blood
Blood (2025) 146 (Supplement 1): 3204.
https://doi.org/10.1182/blood-2025-3204
Published: 2025
Journal Articles

Comparing Immune Reconstitution in Post-Transplant Cy Myeloablative Vs Reduced Intensity Transplants: Notable Trends in Monocyte Population

Free
Manan Shah, Mandi Zhu, Rathan Kumar, Malith Karunasiri, Lotus Neidemire-Colley, Nicholas Yuhasz, Elizabeth Miller, Marcos de Lima, Parvathi Ranganathan, Hannah Choe
Journal: Blood
Blood (2024) 144 (Supplement 1): 7336.
https://doi.org/10.1182/blood-2024-201863
Published: 2024
Journal Articles

Bromodomain/Extra-Terminal Inhibition (BETi) and Ruxolitinib: Immune Profiling Insights from Human Samples in Acute Gvhd

Free
Manan Shah, Rathan Kumar, Lotus Neidemire-Colley, Mandi Zhu, Nicholas Yuhasz, Malith Karunasiri, Parvathi Ranganathan, Hannah Choe
Journal: Blood
Blood (2024) 144 (Supplement 1): 4906.
https://doi.org/10.1182/blood-2024-199900
Published: 2024
Journal Articles

Inhibition of Bromodomain and Extraterminal Domain (BET) Proteins Alleviates Chronic Graft- Versus -Host-Disease Via Modulating the CXCR5/CXCL13 Axis

Free
Rathan Kumar, Lotus Neidermire-Colley, Charlie Spencer, David Aslaner, Yandi Gao, Simran Surana, Matthew W Gorr, Katiri Snyder, Malith Karunasiri, Loren E Wold, Gideon Bollag, Ben Powell, Hannah Choe, Parvathi Ranganathan
Journal: Blood
Blood (2023) 142 (Supplement 1): 2047.
https://doi.org/10.1182/blood-2023-182354
Published: 2023
Journal Articles

Epidermal Growth Factor-like 7 As a Novel Therapeutic Target in Mantle Cell Lymphoma

Free
Chinmayee Goda, Sofia Kolovich, Rohan SUDHIR Kulkarni, Malith Karunasiri, Alex Ruddich, Eric Nauman, Satishkumar Singh, Girish Rajgolikar, Ramiro Garzon, Lalit Sehgal, Adrienne M. Dorrance
Journal: Blood
Blood (2021) 138 (Supplement 1): 3300.
https://doi.org/10.1182/blood-2021-151169
Published: 2021
Journal Articles

Modulating Endothelial Cells with EGFL7 to Diminish aGVHD after Allogeneic Bone Marrow Transplantation in Mice

Free
Martin Guimond, Moutuaata Moutuou, Chinmayee Goda, Nathalie Sell, Sonu Kaylan, Malith Karunasiri, Rohan SUDHIR Kulkarni, Marie Goulard, Sofia Kovovich, Eric Naumann, Antoire Ackaoui, Charles-Etienne Bigras, Francis Daudelin, Alex Ruddich, Ramiro Garzon, Parvathi Ranganathan, Adrienne M. Dorrance
Journal: Blood
Blood (2021) 138 (Supplement 1): 4786.
https://doi.org/10.1182/blood-2021-152740
Published: 2021
Journal Articles

EGFL7 Antagonizes NOTCH Signaling and Represents a Novel Therapeutic Target in Acute Myeloid Leukemia (AML)

Free
Marius Bill, MD PhD, Aparna Pathmanathan, Malith Karunasiri, Changxian Shen, Matthew Burke, Parvathi Ranganathan, PhD, Dimitrios Papaioannou, MD, Nina C. Zitzer, DVM, Katiri Snyder, Allison LaRocco, Allison Walker, Zachary Brannan, Ansel P. Nalin, Aharon G. Freud, MD PhD, Mikhail Dikov, Xiaoli Zhang, PhD, Clara D. Bloomfield, MD, Ramiro Garzon, MD, Adrienne M. Dorrance, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2546.
https://doi.org/10.1182/blood-2019-131856
Published: 2019
Journal Articles

CircPCMTD1 : A Protein-Coding Circular RNA That Regulates DNA Synthesis in Leukemic Myeloblasts

Free
Dimitrios Papaioannou, MD, Remi Buisson, Andreas Petri, PhD, Allison Walker, Marius Bill, MD PhD, Felice Pepe, PhD, Deedra Nicolet, MS, Lauren A Woodward, Krzysztof Mrózek, MD PhD, Malith Karunasiri, Gregory K. Behbehani, MD PhD, Emanuele Cocucci, PhD, Guramrit Singh, PhD, Sakari Kauppinen, PhD, Adrienne M. Dorrance, PhD, Clara D. Bloomfield, MD, Ramiro Garzon, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 640.
https://doi.org/10.1182/blood-2019-126223
Published: 2019
Journal Articles

EGFL7 Antagonizes NOTCH Signaling, Stimulates Blast Proliferation and Confers Poor Prognosis in Cytogenetically-Normal Acute Myeloid Leukemia (CN-AML)

Free
Changxian Shen, Dimitrios Papaioannou, MD, Betina Mcneil, Deedra Nicolet, Malith Karunasiri, Matthew Burke, Zitzer Nina, Gregory K. Behbehani, MD PhD, Hatice G Ozer, PhD, Selen Yilmaz, Guido Marcucci, MD, Michael A. Caligiuri, MD, Clara D. Bloomfield, MD, Ramiro Garzon, MD, Adrienne Dorrance, PhD
Journal: Blood
Blood (2016) 128 (22): 2689.
https://doi.org/10.1182/blood.V128.22.2689.2689
Published: 2016