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Journal Articles

Engraftment and Reconstitution of Hematopoiesis Is Dependent on Endothelial Cell Expressed Prostaglandin EP4 Receptor Signaling Mediated Regeneration of Vascular Niche

Pratibha Singh, PhD, Hongge Li, PhD, Louis M. Pelus, PhD

Blood (2018) 132 (Supplement 1): 1293.

https://doi.org/10.1182/blood-2018-99-119723

Published: 2018

Journal Articles

Attenuation of CXCR4/SDF-1 Axis in Bone Marrow Mesenchymal Stromal Cells Impairs Hematopoietic Niche Activity and Promotes Stem Cell Aging

Pratibha Singh, PhD, Melissa A Kacena, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD

Blood (2017) 130 (Supplement 1): 92.

https://doi.org/10.1182/blood.V130.Suppl_1.92.92

Published: 2017

Journal Articles

Prostaglandin E 2 Prevents Apoptosis and Promotes Homeostasis of Hematopoietic Stem Cells after Lethal Irradiation through Alteration of p53 and TNF Signaling

Andrea M Patterson, PhD, Liqiong Liu, MD PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD

Blood (2017) 130 (Supplement 1): 3766.

https://doi.org/10.1182/blood.V130.Suppl_1.3766.3766

Published: 2017

Journal Articles

Prostaglandin E2 Protects HSC from DNA Damage Induced By Ionizing Radiation By Preventing Generation of Reactive Oxygen Species and Histone Acetylation

Liqiong Liu, MD PhD, Andrea M Patterson, PhD, Hui Lin Chua, PhD, Carol Sampson, MS, Artur Plett, PhD, Hongge Li, PhD, Pratibha Singh, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD

Blood (2017) 130 (Supplement 1): 1151.

https://doi.org/10.1182/blood.V130.Suppl_1.1151.1151

Published: 2017

Journal Articles

Prostaglandin E2 Promotes Recovery of Thymus in Survivors of the Hematopoietic Acute Radiation Syndrome (H-ARS)

TONG WU, MD PhD, Artur Plett, PhD, Hui Lin Chua, PhD, Louis M. Pelus, PhD, Christie M. Orschell, PhD

Blood (2017) 130 (Supplement 1): 1008.

https://doi.org/10.1182/blood.V130.Suppl_1.1008.1008

Published: 2017

Journal Articles

Prostaglandin E 2 Promotes Early Bone Marrow Reconstitution for Survival after Lethal Irradiation

Andrea M. Patterson, PhD, Pratibha Singh, PhD, Hongge Li, PhD, Hui Lin Chua, PhD, Alexa Fisher, BS, Carol Sampson, MS, Artur Plett, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD

Blood (2016) 128 (22): 1481.

https://doi.org/10.1182/blood.V128.22.1481.1481

Published: 2016

Journal Articles

Neuropeptide Y Is Critical for Bone Marrow Stromal Cells and Hematopoietic Recovery Following Injury

Pratibha Singh, PhD, Louis M. Pelus, PhD

Blood (2016) 128 (22): 173.

https://doi.org/10.1182/blood.V128.22.173.173

Published: 2016

Journal Articles

CXCR4-SDF-1 Signaling in Nestin+ Mesenchymal Stem Cell Is Required for HSC Maintenance during Homeostasis and Regeneration after Irradiation

Pratibha Singh, PhD, Louis M. Pelus, PhD

Blood (2016) 128 (22): 3883.

https://doi.org/10.1182/blood.V128.22.3883.3883

Published: 2016

Journal Articles

Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell

Jonathan Hoggatt, PhD, Pratibha Singh, PhD, Tiffany Tate, BS, Peter V. Kharchenko, PhD, Amir Schajnovitz, PhD, Ninib Barawnyo, PhD, Francois Mercier, MD, Dwight Morrow, PhD, David T. Scadden, MD, Louis M. Pelus, PhD

Blood (2016) 128 (22): 368.

https://doi.org/10.1182/blood.V128.22.368.368

Published: 2016

Journal Articles

Prostaglandin E2 Signaling through EP4 Receptor Promotes Hematopoietic Stem Cell Niche Regeneration and Enhances Hematopoietic Recovery

Pratibha Singh, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD

Blood (2015) 126 (23): 784.

https://doi.org/10.1182/blood.V126.23.784.784

Published: 2015

Journal Articles

Mitigation of a Newly Discovered Phenomenon, Extra Physiologic Oxygen Shock/Stress (EPHOSS), Mediated By the Mitochondria Permeability Transition Pore, Greatly Improves Stem Cell Collection and Transplantation

Charlie Mantel, Heather A. O'Leary, PhD, Brahmananda Reddy Chitteti, PhD, Xinxin Huang, PhD, Scott Cooper, BS, Giao Hangoc, DVM, PhD, Nickolay Brustovetsky, PhD, Edward F. Srour, PhD, Man Ryul Lee, PhD, Steven Messina-Graham, Nadia Falah, MD, Reuben Kapur, PhD, Louis M. Pelus, PhD, Mircea Ivan, MD, PhD, Kye-Seong Kim, PhD, Hal E. Broxmeyer, PhD

Blood (2014) 124 (21): 2905.

https://doi.org/10.1182/blood.V124.21.2905.2905

Published: 2014

Journal Articles

Survivin Is a Master Regulator of Mesenchymal Stem Cell Functions and Potential Therapeutic Target for Mesenchymal Stem Cell Expansion

Pratibha Singh, PhD, Seiji Fukuda, MD PhD, Mary R. Saunders, PhD, Louis M. Pelus, PhD

Blood (2014) 124 (21): 774.

https://doi.org/10.1182/blood.V124.21.774.774

Published: 2014

Journal Articles

Bone Marrow Sinusoidal Integrity Regulates Hematopoietic Stem and Progenitor Cell Trafficking

Pratibha Singh, PhD, Khalid Mohammad, PhD, Jonathan Hoggatt, PhD, Jennifer M. Speth, PhD, Louis M. Pelus, PhD

Blood (2013) 122 (21): 3687.

https://doi.org/10.1182/blood.V122.21.3687.3687

Published: 2013

Journal Articles

Hif1α and Rac1 Are Necessary For Enhanced HSPC Migration and Homing In Response To Prostaglandin E 2 Treatment

Jennifer M. Speth, PhD, Maegan L. Capitano, Ph.D., Jonathan Hoggatt, PhD, Louis M. Pelus, PhD

Blood (2013) 122 (21): 889.

https://doi.org/10.1182/blood.V122.21.889.889

Published: 2013

Journal Articles

The Internal-Tandem-Duplication of Flt3 Mutation Generates Growth Inhibitory Signals in Mouse Hematopoietic Progenitor Cells by Down-Regulating Pbx1 Expression Via P21 cdkn1a .

Seiji Fukuda, MD, PhD, Mariko Abe, MD, Tomohiro Hirade, MD, Chie Onishi, MD, Louis M. Pelus, PhD, Seiji Yamaguchi, MD

Blood (2012) 120 (21): 2340.

https://doi.org/10.1182/blood.V120.21.2340.2340

Published: 2012

Journal Articles

Sinusoidal Endothelial CD26 Cleavage of Neuropeptide Y Regulates Transendothelial Migration and Mobilization of Hematopoietic Stem and Progenitor Cells in Response to G-CSF.

Pratibha Singh, PhD, Jonathan Hoggatt, Ph.D., Peirong Hu, PhD, Louis M. Pelus, PhD

Blood (2012) 120 (21): 2347.

https://doi.org/10.1182/blood.V120.21.2347.2347

Published: 2012

Journal Articles

CD166 (ALCAM): A Functional Marker of Primitive Murine and Human Hematopoietic Stem Cells and Cellular Elements of Their Niche

Brahmananda Reddy Chitteti, PhD, MIchihiro Kobayashi, M.D., Ph.D., Yinghua Cheng, M.D., Peirong Hu, PhD, Bradley Poteat, Hal E. Broxmeyer, Ph.D., Louis M. Pelus, PhD, Melissa A. Kacena, PhD, Edward F. Srour, Ph.D.

Blood (2012) 120 (21): 640.

https://doi.org/10.1182/blood.V120.21.640.640

Published: 2012

Journal Articles

Enhanced Homing of HSPCs After Treatment with Prostaglandin E2 (PGE 2 ) May Be An Effect of Transcriptional Regulation of CXC Chemokine Receptor 4 (CXCR4) Through Hypoxia Inducible Factor 1α (HIF1α)

Jennifer M Speth, Jonathan Hoggatt, Ph.D., Louis M. Pelus, PhD

Blood (2011) 118 (21): 918.

https://doi.org/10.1182/blood.V118.21.918.918

Published: 2011

Journal Articles

Bone Marrow Niche Attenuation by Non-Steroidal Anti-Inflammatory Drugs Mobilizes Hematopoietic Stem and Progenitor Cells by Differing Mechanisms

Jonathan Hoggatt, Ph.D., Khalid S Mohammad, M.D. Ph.D., Brahmananda Reddy Chitteti, PhD, Pratibha Singh, PhD, Jennifer M Speth, Peirong Hu, PhD, Bradley Poteat, Edward Srour, PhD, Theresa Guise, M.D., Louis M. Pelus, PhD

Blood (2011) 118 (21): 724.

https://doi.org/10.1182/blood.V118.21.724.724

Published: 2011

Journal Articles

CXCR4-SDF-1 Signaling Mediated up-Regulation of Survivin Expression In Mesenchymal Progenitor Cells Is Critical for Their Proliferation and Maintenance of Osteoblastic Niche

Pratibha Singh, PhD, Jennifer Speth, Peirong Hu, PhD, Louis M. Pelus, PhD

Blood (2010) 116 (21): 941.

https://doi.org/10.1182/blood.V116.21.941.941

Published: 2010

NARROW

Engraftment and Reconstitution of Hematopoiesis Is Dependent on Endothelial Cell Expressed Prostaglandin EP4 Receptor Signaling Mediated Regeneration of Vascular Niche

Attenuation of CXCR4/SDF-1 Axis in Bone Marrow Mesenchymal Stromal Cells Impairs Hematopoietic Niche Activity and Promotes Stem Cell Aging

Prostaglandin E 2 Prevents Apoptosis and Promotes Homeostasis of Hematopoietic Stem Cells after Lethal Irradiation through Alteration of p53 and TNF Signaling

Prostaglandin E2 Protects HSC from DNA Damage Induced By Ionizing Radiation By Preventing Generation of Reactive Oxygen Species and Histone Acetylation

Prostaglandin E2 Promotes Recovery of Thymus in Survivors of the Hematopoietic Acute Radiation Syndrome (H-ARS)

Prostaglandin E 2 Promotes Early Bone Marrow Reconstitution for Survival after Lethal Irradiation

Neuropeptide Y Is Critical for Bone Marrow Stromal Cells and Hematopoietic Recovery Following Injury

CXCR4-SDF-1 Signaling in Nestin+ Mesenchymal Stem Cell Is Required for HSC Maintenance during Homeostasis and Regeneration after Irradiation

Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell

Prostaglandin E2 Signaling through EP4 Receptor Promotes Hematopoietic Stem Cell Niche Regeneration and Enhances Hematopoietic Recovery

Mitigation of a Newly Discovered Phenomenon, Extra Physiologic Oxygen Shock/Stress (EPHOSS), Mediated By the Mitochondria Permeability Transition Pore, Greatly Improves Stem Cell Collection and Transplantation

Survivin Is a Master Regulator of Mesenchymal Stem Cell Functions and Potential Therapeutic Target for Mesenchymal Stem Cell Expansion

Bone Marrow Sinusoidal Integrity Regulates Hematopoietic Stem and Progenitor Cell Trafficking

Hif1α and Rac1 Are Necessary For Enhanced HSPC Migration and Homing In Response To Prostaglandin E 2 Treatment

The Internal-Tandem-Duplication of Flt3 Mutation Generates Growth Inhibitory Signals in Mouse Hematopoietic Progenitor Cells by Down-Regulating Pbx1 Expression Via P21 cdkn1a .

Sinusoidal Endothelial CD26 Cleavage of Neuropeptide Y Regulates Transendothelial Migration and Mobilization of Hematopoietic Stem and Progenitor Cells in Response to G-CSF.

CD166 (ALCAM): A Functional Marker of Primitive Murine and Human Hematopoietic Stem Cells and Cellular Elements of Their Niche

Enhanced Homing of HSPCs After Treatment with Prostaglandin E2 (PGE 2 ) May Be An Effect of Transcriptional Regulation of CXC Chemokine Receptor 4 (CXCR4) Through Hypoxia Inducible Factor 1α (HIF1α)

Bone Marrow Niche Attenuation by Non-Steroidal Anti-Inflammatory Drugs Mobilizes Hematopoietic Stem and Progenitor Cells by Differing Mechanisms

CXCR4-SDF-1 Signaling Mediated up-Regulation of Survivin Expression In Mesenchymal Progenitor Cells Is Critical for Their Proliferation and Maintenance of Osteoblastic Niche

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American Society of Hematology

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ASH Publications

American Society of Hematology

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