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Journal Articles

Metformin Suppress Cellular and Molecular Processes Related to Maintenance and Proliferation of Myeloproliferative Neoplasm Stem Cell

Juan L Coelho-Silva, BSc, MSc, Thiago Mantello Bianco, MSc, Antonio Bruno Alves Silva, BSc, Diego Antonio Pereira-Martins, M.Sc., Natasha Peixoto Fonseca, B.Sc., M.Sc., Isabel Weinhäuser, MSc, Eduardo M Rego, MD PhD, Fernando Chahud, MD PhD, João Agostinho Machado-Neto, PhD, Lorena Lobo Figueiredo-Pontes, MD PhD, Fabiola Traina, MD PhD

Blood (2019) 134 (Supplement_1): 1682.

https://doi.org/10.1182/blood-2019-132115

Published: 2019

Journal Articles

Efficacy of the Pan-Bcl-2 Inhibitor (Obatoclax) As a Single Agent to Treat Myeloproliferative Neoplasm in JAK2V617F Murine Transplantation Model

Thiago Mantello Bianco, MSc, Juan L Coelho-Silva, BSc, MSc, Diego A Pereira-Martins, MSc, Priscila Santos Scheucher, PhD, Isabel Weinhäuser, MSc, Antonio Bruno Alves Silva, BSc, Cleide Lucia Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo M Rego, MD PhD, Fabiola Traina, MD PhD, Lorena Lobo Figueiredo-Pontes, MD PhD

Blood (2019) 134 (Supplement_1): 2977.

https://doi.org/10.1182/blood-2019-131023

Published: 2019

Journal Articles

Reduced SLIT2 Are Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in APL Cells

Isabel Weinhäuser, MSc, Diego A Pereira-Martins, MSc, Luíse A A Simões, BSc, César Alexander Ortiz Rojas, BSc, Thiago Mantello Bianco, MSc, Cleide Lucia Silva, MSc, Mariane Cristina Do Nascimento, BSc, Lorena Lobo Figueiredo-Pontes, MD PhD, Antonio R. Lucena-Araujo, PhD, Eduardo M Rego, MD PhD

Blood (2019) 134 (Supplement_1): 5165.

https://doi.org/10.1182/blood-2019-131496

Published: 2019

Journal Articles

The Scenario of Myelofibrosis in Brazil in the View of a Panel of Experts: Challenges and Proposals

Laura Maria Fogliatto, MD PhD, Cristiana Solza, MD PhD, Alexandre Gustavo Apa, MD, Gustavo HR Magalhaes, MD MSc, Marcia Torresan Delamain, MD, Renato Tavares, MD, Lorena Lobo Figueiredo-Pontes, MD PhD

Blood (2019) 134 (Supplement_1): 5851.

https://doi.org/10.1182/blood-2019-121960

Published: 2019

Journal Articles

Experience of Generic Imatinib As a First Line Therapy for Patients with Chronic Myeloid Leukemia in a Single Reference Institution

Gabriel Carvalho Pereira, MD, Fernanda B da Silva, BSc and MSc, Luisa Espirito Santo Oliveira, Pedro Marques Garibaldi, MD, Lorena Lobo Figueiredo-Pontes, MD PhD, Belinda Pinto Simões, MD PhD, Leonardo Carvalho Palma, MD PhD, Fabiola Traina, MD PhD

Blood (2019) 134 (Supplement_1): 5916.

https://doi.org/10.1182/blood-2019-132045

Published: 2019

Journal Articles

Clinical and Functional Studies Reveal That TP73 Isoforms Levels Are Associated with Prognosis and RA-Resistance in Acute Promyelocytic Leukemia

Blood (2019) 134 (Supplement_1): 2719.

https://doi.org/10.1182/blood-2019-131211

Published: 2019

Journal Articles

C/Ebpg (CCAAT/Enhancer Binding Protein Gamma) Balances Cytotoxic and Secretory Potential of Natural Killer Cells

Izabela Aparecida Lopes, MSc, Miroslava Kardosova, MSc, Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Cleide Araújo Silva, MSc, Priscila Santos Scheucher, PhD, Daniel G. Tenen, MD, Sanghoon Lee, PhD, Eduardo Magalhães Rego, MD PhD, Robert S. Welner, PhD, Meritxell Alberich-Jorda, Lorena Lobo Figueiredo-Pontes, MD PhD

Blood (2018) 132 (Supplement 1): 3721.

https://doi.org/10.1182/blood-2018-99-119389

Published: 2018

Journal Articles

NSD1 and NSD2 Transcriptional Levels Might Predict Clinical Outcome in AML Patients

Virginia Mara De Deus Wagatsuma, PhD, Diego Antonio Pereira-Martins, MSc, Mariane Cristina Do Nascimento, BSc, Silvia Elena Sanchez Mendoza, Antonio R. Lucena-Araujo, PhD, Aleide Lima, MSc, Felipe Saldanha-Araujo, PhD, Fabio Pitella, PhD, Fabiola Traina, MD PhD, Maria Isabel A Madeira, MSc, MD, Lorena Lobo Figueiredo-Pontes, MD PhD, Eduardo Magalhães Rego, MD PhD

Blood (2018) 132 (Supplement 1): 5257.

https://doi.org/10.1182/blood-2018-99-119411

Published: 2018

Journal Articles

Abnormal Distribution and Function of NK Cells Subsets May Lead to Impaired Tumor Surveillance in a JAK2V617F Myeloproliferative Neoplasm Model

Thiago Mantello Bianco, MSc, Diego Antonio Pereira-Martins, MSc, Patrícia Vianna Bonini Palma, BSc, Josiane Lilian Schiavinato, PhD, Cleide Araújo Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo Magalhães Rego, MD PhD, Lorena Lobo Figueiredo-Pontes, MD PhD

Blood (2018) 132 (Supplement 1): 4335.

https://doi.org/10.1182/blood-2018-99-115006

Published: 2018

Journal Articles

The Pharmacological IGF1R-IRS1/2 Inhibitor NT157 Presents Multiple Anti-Neoplastic Effects in Myeloproliferative Neoplasms

Bruna Alves Fenerich, BSc, João Agostinho Machado-Neto, BSc, Ana Paula Nunes Rodrigues Alves, MSc, Paula De Melo Campos, MD PhD, Jaqueline Cristina Fernandes, BSc, MSc, Juan Luiz Coelho-Silva, BSc, MSc, Renata Scopim Ribeiro, BSc, MSc, Fernanda B da Silva, BSc and MSc, Priscila Santos Scheucher, PhD, Lorena Lobo Figueiredo-Pontes, MD PhD, Eduardo Magalhães Rego, MDPhD, Fabiola Traina, MD PhD

Blood (2017) 130 (Supplement 1): 1253.

https://doi.org/10.1182/blood.V130.Suppl_1.1253.1253

Published: 2017

Journal Articles

Imbalance between Tolerant and Cytotoxic Functional Subsets of NK Cells in a JAK2 V617F Myeloproliferative Neoplasm Model

Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Izabela Aparecida Lopes, MSc, Priscila Santos Scheucher, PhD, Cleide Araújo Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo Magalhães Rego, MDPhD, Lorena Lobo Figueiredo-Pontes, MD PhD

Blood (2017) 130 (Supplement 1): 4221.

https://doi.org/10.1182/blood.V130.Suppl_1.4221.4221

Published: 2017

Journal Articles

Metformin Reduces Tumor Burden and Splenomegaly in JAK2 V617F Murine Models

João Agostinho Machado-Neto, BSc, Renata Scopim Ribeiro, BSc, MSc, Juan Luiz Coelho-Silva, BSc, MSc, Christopher A. Eide, Bruna Alves Fenerich, BSc, Jaqueline Cristina Fernandes, BSc, MSc, Ana Paula Nunes Rodrigues Alves, MSc, Priscila S Scheucher, PhD, Cristina E. Tognon, PhD, Lorena Lobo Figueiredo-Pontes, MD PhD, Brian J. Druker, MD, Eduardo Magalhães Rego, MDPhD, Fabiola Traina, MD PhD

Blood (2017) 130 (Supplement 1): 4222.

https://doi.org/10.1182/blood.V130.Suppl_1.4222.4222

Published: 2017

Journal Articles

Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) Family Members Expression in Acute Myeloid Leukemia

Virginia Mara De Deus Wagatsuma, PhD, Luisa C A Koury, MD, Silvia Elena Sánchez, MSc, Lorena Lobo Figueiredo Pontes, MD; PhD, Fernanda Borges da Silva, MSc, Adriana Ines Dore, Biologist, Ana Silvia Gouvêa de Lima, PhD, Antonio R. Lucena-Araujo, PhD, Luciana Yamamoto Almeida, PhD, Fabiola Traina, MD, PhD, Felipe Saldanha-Araújo, PhD, Fabio Pittella-Silva, PhD, Eduardo Magalhães Rego, MD, PhD

Blood (2016) 128 (22): 5097.

https://doi.org/10.1182/blood.V128.22.5097.5097

Published: 2016

Journal Articles

Cytokine-Mediated Natural Killer Cells Effects Impair Hematopoietic Stem Cell Function

Lorena Lobo Figueiredo-Pontes, MD, PhD, Robert S. Welner, PhD, Miroslava Kardosova, Hong Zhang, PhD, Meritxell Alberich-Jorda, Daniel G. Tenen

Blood (2016) 128 (22): 2641.

https://doi.org/10.1182/blood.V128.22.2641.2641

Published: 2016

Journal Articles

The Use of Cyclosporine in Association with Chemotherapy As Induction Treatment in Patients with Acute Myeloid Leukemia (AML) and High Rhodamine Efflux at Diagnosis Results in Higher Complete Hematological Remission Rates, but Does Not Prolong Overall Survival

Luisa C A Koury, Graduate Student, Lorena Lobo Figueiredo-Pontes, MD PhD, Belinda Pinto Simoes, MD, PhD, Luciana C O Oliveira, MD, Leandro F F Dalmazzo, MD, Maria Carolina Tostes Pintão, MD, Aglair B Garcia, Roberto Passetto Falcão, MD PhD, Eduardo Magalhães Rego, MD, PhD

Blood (2015) 126 (23): 4896.

https://doi.org/10.1182/blood.V126.23.4896.4896

Published: 2015

Journal Articles

Decreased Activity of NK Cells in Myeloproliferative Neoplasms

Adriana Queiroz Arantes, MD, Cristina Tavares Leal, MD, Cleide Araújo Silva, Priscila Santos Scheucher, PhD, Aglair Bergamo, Robert S. Welner, PhD, Daniel G. Tenen, MD, Ann Mullally, MD, Susumu Kobayashi, MD PhD, Eduardo Magalhaes Rego, PhD, Lorena Lobo Figueiredo-Pontes, MD, PhD

Blood (2015) 126 (23): 1637.

https://doi.org/10.1182/blood.V126.23.1637.1637

Published: 2015

Journal Articles

Dysregulation Of Bcl2 Family Proteins Induced By JAK2 V617F Mutation Contributes To The Abnormal Expansion Of Neoplastic Initiating Cells

Lorena Lobo Figueiredo-Pontes, MD, PhD, Robert S Welner, PhD, Yuta Mishima, PhD, Mihoko Yamamoto, MS, Ann Mullally, MD, Daniel G. Tenen, MD, Susumu Kobayashi, MD, PhD

Blood (2013) 122 (21): 2852.

https://doi.org/10.1182/blood.V122.21.2852.2852

Published: 2013

Journal Articles

Cytogenetics and spectral Karyotyping analysis in CLL Patients: Correlation with FISH and ZAP70 Expression

Fabio Morato Oliveira, PhD, Daniel Mazza Matos, MD, PhD, Lorena Lobo Figueiredo Pontes, MD, PhD, Belinda Pinto Simoes, MD, PhD, Eduardo M. Rego, MD, PhD, Roberto P. Falcao, MD, PhD

Blood (2010) 116 (21): 4844.

https://doi.org/10.1182/blood.V116.21.4844.4844

Published: 2010

Journal Articles

Spectral Karyotyping (SKY) ANALYSIS APPLIED to CHRONIC LYMPHOCYTIC LEUKEMIA CELLS Immunostimulated with the COMBINATION DSP30/IL-2.

Fabio Morato Oliveira, PhD, Daniel Mazza Matos, MD, PhD, Lorena Lobo Figueiredo-Pontes, MD, PhD, Belinda Simoes, MD, PhD, Eduardo M. Rego, MD, PhD, Roberto P Falcao, MD, PhD

Blood (2009) 114 (22): 4692.

https://doi.org/10.1182/blood.V114.22.4692.4692

Published: 2009

NARROW

Metformin Suppress Cellular and Molecular Processes Related to Maintenance and Proliferation of Myeloproliferative Neoplasm Stem Cell

Efficacy of the Pan-Bcl-2 Inhibitor (Obatoclax) As a Single Agent to Treat Myeloproliferative Neoplasm in JAK2V617F Murine Transplantation Model

Reduced SLIT2 Are Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in APL Cells

The Scenario of Myelofibrosis in Brazil in the View of a Panel of Experts: Challenges and Proposals

Experience of Generic Imatinib As a First Line Therapy for Patients with Chronic Myeloid Leukemia in a Single Reference Institution

Clinical and Functional Studies Reveal That TP73 Isoforms Levels Are Associated with Prognosis and RA-Resistance in Acute Promyelocytic Leukemia

C/Ebpg (CCAAT/Enhancer Binding Protein Gamma) Balances Cytotoxic and Secretory Potential of Natural Killer Cells

NSD1 and NSD2 Transcriptional Levels Might Predict Clinical Outcome in AML Patients

Abnormal Distribution and Function of NK Cells Subsets May Lead to Impaired Tumor Surveillance in a JAK2V617F Myeloproliferative Neoplasm Model

The Pharmacological IGF1R-IRS1/2 Inhibitor NT157 Presents Multiple Anti-Neoplastic Effects in Myeloproliferative Neoplasms

Imbalance between Tolerant and Cytotoxic Functional Subsets of NK Cells in a JAK2 V617F Myeloproliferative Neoplasm Model

Metformin Reduces Tumor Burden and Splenomegaly in JAK2 V617F Murine Models

Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) Family Members Expression in Acute Myeloid Leukemia

Cytokine-Mediated Natural Killer Cells Effects Impair Hematopoietic Stem Cell Function

The Use of Cyclosporine in Association with Chemotherapy As Induction Treatment in Patients with Acute Myeloid Leukemia (AML) and High Rhodamine Efflux at Diagnosis Results in Higher Complete Hematological Remission Rates, but Does Not Prolong Overall Survival

Decreased Activity of NK Cells in Myeloproliferative Neoplasms

Dysregulation Of Bcl2 Family Proteins Induced By JAK2 V617F Mutation Contributes To The Abnormal Expansion Of Neoplastic Initiating Cells

Cytogenetics and spectral Karyotyping analysis in CLL Patients: Correlation with FISH and ZAP70 Expression

Spectral Karyotyping (SKY) ANALYSIS APPLIED to CHRONIC LYMPHOCYTIC LEUKEMIA CELLS Immunostimulated with the COMBINATION DSP30/IL-2.

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American Society of Hematology

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American Society of Hematology

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