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Journal Articles

Transcriptome Sequencing Reveals Alternative Splicing Patterns and an Increased Sensitivity to Spliceosome Inhibition Associated MYD88 L265P Mutation in Chronic Lymphocytic Leukemia

Shuchao Qin, PhD, Xinyu Zhang, MBBS, Qimei Han, MBBS, Chang-Sheng Chang, PhD, Eun-Jeong Park, PhD, Lirong Pei, PhD, Chandraiah Lagisetti, PhD, Thomas R Webb, PhD, Jiazhu Wu, MD, Wei Xu, MD PhD, Jianyong Li, MD PhD, Huidong Shi, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5535.
https://doi.org/10.1182/blood-2018-99-118667
Published: 2018
Journal Articles

SF3B1 Mutation Causes Aberrant Splicing and Downregulation of PPP2R5A in Chronic Lymphocytic Leukemia

Qimei Han, MBBS, Libin Deng, PhD, Lirong Pei, Jeong-Hyeon Choi, PhD, Victor Jin, PhD, Huidong Shi
Journal: Blood
Blood (2017) 130 (Supplement 1): 2477.
https://doi.org/10.1182/blood.V130.Suppl_1.2477.2477
Published: 2017
Journal Articles

CDK7 Inhibitor THZ1 Inhibits Glycolytic Metabolism By Suppressing HIF1α Activity in Chronic Lymphocytic Leukemia

Shuchao Qin, MBBS, Austin Young Shull, Qimei Han, MBBS, Lirong Pei, Farrukh T. Awan, MD MS, Wei Xu, Jianyong Li, MD PhD, Huidong Shi
Journal: Blood
Blood (2017) 130 (Supplement 1): 3811.
https://doi.org/10.1182/blood.V130.Suppl_1.3811.3811
Published: 2017
Journal Articles

DNA Hypomethylation within B-Cell Enhancers and Super Enhancers Reveal a Dependency on Immune and Metabolic Mechanisms in Chronic Lymphocytic Leukemia

Austin Y. Shull, PhD, Junfeng Luo, PhD, Lirong Pei, Eun-Joon Lee, PhD, Jimei Liu, PhD, Justin Choi, PhD, Farrukh T. Awan, Huidong Shi, PhD
Journal: Blood
Blood (2016) 128 (22): 1049.
https://doi.org/10.1182/blood.V128.22.1049.1049
Published: 2016
Journal Articles

Genome-Wide DNA Methylation Analysis Identifies Aberrant Epigenetic Changes in CD8+ T Cells from Chronic Lymphocytic Leukemia Patients

Jiazhu Wu, B. S., Xiaojing Xu, PhD, Lirong Pei, B.S., Eun-Joon Lee, PhD, Austin Shull, B.S., Farrukh Awan, MD MS, Xiaoling Wang, PhD, Lei Fan, MD, PhD, Li Jianyong, MD PhD, Xu Wei, MD PhD, Huidong Shi, PhD
Journal: Blood
Blood (2014) 124 (21): 3552.
https://doi.org/10.1182/blood.V124.21.3552.3552
Published: 2014
Journal Articles

DNA Hypomethylation Leads to Aberrant Expression of PD-1 in Chronic Lymphocytic Leukemia

Eun Joon Lee, Ph.D., Jimei Liu, Ph.D., Ethan Speir, James Wilson, B.S., Hena Joshi, B.S., Lirong Pei, B.S., Junfeng Luo, Ph.D., Farrukh Awan, M.D., M.S., David Munn, M.D., Xiao-Jie Yan, M.D., Ph.D., Nicholas Chiorazzi, MD, Huidong Shi, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 3504.
https://doi.org/10.1182/blood.V120.21.3504.3504
Published: 2012
Journal Articles

Genome-Wide DNA Methylation Landscape Defines IGHV Mutated and Unmutated B Cell Chronic Lymphocytic Leukemias

Junfeng Luo, Ph.D., Justin Choi, Ph.D., Lirong Pei, B.S., Farrukh Awan, M.D., M.S., Eun-Joon Lee, Ph.D., Jimei Liu, Ph.D., Austin Shull, B.S., Brian A. McCarthy, Ph.D., James M. Wilson, B.S., Kristen H. Taylor, Ph.D., Xinguo Wang, Ph.D., Phillip Joe Buckhaults, Ph.D., David H. Munn, M.D., Charles W. Caldwell, M.D., Ph.D., Xiao-Jie Yan, M.D., Ph.D., Nicholas Chiorazzi, MD, Huidong Shi, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 526.
https://doi.org/10.1182/blood.V120.21.526.526
Published: 2012