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Lingling Xian, MD PhD
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Journal Articles

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

Alison R. Moliterno, MD, Donna Marie Williams, PhD, Liping Li, MD PhD, Lingling Xian, MD PhD, Li Luo, PhD, Amy S. Duffield, MD PhD, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 472.
https://doi.org/10.1182/blood-2019-131432
Published: 2019
Journal Articles

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

Liping Li, MD PhD, Katharina Hayer, Lingling Xian, MD PhD, Li Luo, PhD, Leslie Cope, Andrei Thomas-Tikhonenko, PhD, Linda Resar, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3946.
https://doi.org/10.1182/blood-2019-130261
Published: 2019
Journal Articles

High Mobility Group A1 Chromatin Regulators: Key Epigenetic Switches and Therapeutic Targets Required for Leukemic Transformation in JAK2 Mutant MPN

Liping Li, MD PhD, Wenyan Lu, PhD, Alison R. Moliterno, MD, Lingling Xian, MD PhD, Joseph Kim, BS, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1680.
https://doi.org/10.1182/blood-2019-130262
Published: 2019
Journal Articles

High Mobility Group A1 Chromatin Remodeling Proteins Amplify Inflammatory Networks to Drive Leukemic Transformation in Chronic Myeloproliferative Neoplasia in Humans and JAK2 V617F Transgenic Mouse Models

Linda Resar, MD, Donna Marie Williams, PhD, Lingling Xian, MD PhD, Wenyan Lu, PhD, Briyana Chisholm, BS, Li Luo, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Jerry L. Spivak, MD, Alison R. Moliterno, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 102.
https://doi.org/10.1182/blood-2018-99-119549
Published: 2018
Journal Articles

High Mobility Group A1 Chromatin Remodeling Proteins: Potential Therapeutic Targets Involved in Polycythemia Vera Transformation to Acute Leukemia in Humans and JAK2 V617F Transgenic Mouse Models

Linda Resar, MD, Donna Marie Williams, PhD, Lingling Xian, MD PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Jerry L. Spivak, MD, Alison R. Moliterno, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 489.
https://doi.org/10.1182/blood.V130.Suppl_1.489.489
Published: 2017
Journal Articles

High Mobility Group A1/2 Chromatin Remodeling Proteins Associate with Polycythemia Vera Transformation to Acute Leukemia in Humans and a JAK2 V617F Transgenic Mouse Model

Linda Resar, MD, Donna Marie Williams, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Lingling Xian, MD PhD, Jerry L. Spivak, MD, Alison R Moliterno, MD
Journal: Blood
Blood (2016) 128 (22): 1958.
https://doi.org/10.1182/blood.V128.22.1958.1958
Published: 2016
Journal Articles

High Mobility Group A1 Chromatin Remodeling Protein Regulates Self-Renewal, Niche Formation, and Regenerative Function in Adult Stem Cells through Wnt/β-Catenin Signaling

Linda Resar, MD, Lingling Xian, MD PhD, Tait Huso, Amy Belton, PhDBSc, Leslie Cope, PhDBSc, David Huso, DVM, PhD
Journal: Blood
Blood (2016) 128 (22): 2647.
https://doi.org/10.1182/blood.V128.22.2647.2647
Published: 2016
Journal Articles

A Novel Feed-Forward Loop Involving the High Mobility Group A1 (HMGA1) Chromatin Remodeling Protein and cMYC in Acute Myeloid Leukemia Is Targeted By JQ1

Linda Resar, MD, Stuart A Rushworth, PhDBSc, Lingling Xian, MD PhD, Kristian Bowles, MB BS, PhD FRCP, FRCPath
Journal: Blood
Blood (2015) 126 (23): 2466.
https://doi.org/10.1182/blood.V126.23.2466.2466
Published: 2015
Journal Articles

High Mobility Group A1 (HMGA1) Chromatin Remodeling Protein Mediates Crosstalk Between Acute Myeloid Leukemia Blasts & the Tumor Microenvironment

Stuart A Rushworth, PhD, Lyubov Zaitseva, PhD, Lingling Xian, MD PhD, Kristian M Bowles, MB BS, PhD, Linda M. S. Resar, MD
Journal: Blood
Blood (2014) 124 (21): 3564.
https://doi.org/10.1182/blood.V124.21.3564.3564
Published: 2014