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Journal Articles

TET2-Mediated Dysregulation of Heterochromatin in Age-Related Clonal Hematopoiesis

Tingting Hong, Jia Li, Lei Guo, Maryn Cavalier, Tianlu Wang, Shaohai Fang, Anna Guzman, Katharina Wohlan, Chiraag Kapadia, Yaling Yang, C. Cameron Yin, Shaoying Li, M. James You, Xiaodong Cheng, Yubin Zhou, Margaret Goodell, Yun Nancy Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5606.
https://doi.org/10.1182/blood-2023-178792
Published: 2023
Journal Articles

A Combination Strategy Targeting Enhancer Plasticity Exerts Synergistic Lethality Against Beti-Resistant Leukemia Cells

Lei Guo, PhD, Jia Li, PhD, Hongxiang Zeng, PhD, Anna Guzman, Tingting Li, MD, Minjung Lee, MS, Yubin Zhou, PhD, Clifford Stephan, Peter J.A Davies, Margaret Goodell, PhD, Deqiang Sun, PhD, Mark A. Dawson, PhD MBBS, Yun Huang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5053.
https://doi.org/10.1182/blood-2019-130586
Published: 2019
Journal Articles

Synthetic Lethality of Combinatory Inhibition of BET and CDK7 in BET(i) Resistant Leukemia Cells

Lei Guo, PhD, Jia Li, PhD, Shaohai Fang, MS, Minjung Lee, MS, Hongxiang Zeng, PhD, Tingting Li, MD, Wei Han, MS, Deqiang Sun, PhD, Yun Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1354.
https://doi.org/10.1182/blood-2018-99-116634
Published: 2018
Journal Articles

Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia

Rong Chen, Lei Guo, Yuling Chen, Yingjun Jiang, William G. Wierda, William Plunkett
Journal: Blood
Blood (2011) 117 (1): 156–164.
https://doi.org/10.1182/blood-2010-01-262808
Published: 2011
Includes: Supplemental data
Journal Articles

Reducing Mcl-1 by Homoharringtonine Induces Apoptosis In Chronic Lymphocytic Leukemia Cells

Rong Chen, PhD, Lei Guo, MD, PhD, Yuling Chen, Yingjun Jiang, PhD, William G. Wierda, MD, PhD, William Plunkett, PhD
Journal: Blood
Blood (2010) 116 (21): 2896.
https://doi.org/10.1182/blood.V116.21.2896.2896
Published: 2010