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Laya Soleimani
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Journal Articles

Spatial transcriptomic dissection of the myeloproliferative neoplasm niche uncovers mutant clone interactions and microenvironmental rewiring

Free
Honghao Bi, Pan Wang, Ching Man Wai, Kehan Ren, Xu Han, Ermin Li, Laya Soleimani, Inci Aydemir, Wenjie Cai, Johanna Melo-Cardenas, Peng Ji
Journal: Blood
Blood (2025) 146 (Supplement 1): 3761.
https://doi.org/10.1182/blood-2025-3761
Published: 2025
Journal Articles

DHODH-driven pyrimidine metabolism is a targetable vulnerability in myeloproliferative neoplasms

Free
Pan Wang, Xu Han, Inci Aydemir, Ermin Li, Honghao Bi, Kehan Ren, Wenjie Cai, Laya Soleimani, Peng Ji
Journal: Blood
Blood (2025) 146 (Supplement 1): 69.
https://doi.org/10.1182/blood-2025-69
Published: 2025
Journal Articles

Plek2 as a novel downstream effector of p53: Targeting Plek2 ameliorates disease progression in p53-deficient myeloid malignancies

Free
Pan Wang, Xu Han, Honghao Bi, Ermin Li, Kehan Ren, Inci Aydemir, Wenjie Cai, Laya Soleimani, Peng Ji
Journal: Blood
Blood (2025) 146 (Supplement 1): 216.
https://doi.org/10.1182/blood-2025-216
Published: 2025
Journal Articles

Modeling germline DDX41 and/or CHEK2 mutations using patient-derived bone marrow Organoids

Free
Inci Aydemir, Xu Han, Honghao Bi, Ermin Li, Kehan Ren, Pan Wang, Laya Soleimani, Madina Sukhanova, Lucy Godley, Peng Ji
Journal: Blood
Blood (2025) 146 (Supplement 1): 1444.
https://doi.org/10.1182/blood-2025-1444
Published: 2025