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Journal Articles

The Immunophilin FKBP12 Inhibits Hepcidin By Modulating BMP Type I-Type II Receptors Interaction and Ligand Responsiveness

Alessandro Dulja, MSc, Alessia Pagani, PhD, Mariateresa Pettinato, Antonella Nai, PhD, Clara Camaschella, MD, Laura Silvestri, PhD

Blood (2019) 134 (Supplement_1): 430.

https://doi.org/10.1182/blood-2019-130058

Published: 2019

Journal Articles

Targeting the BMP Receptor Inhibitor FKBP12 to Upregulate Hepcidin in Wild-Type and Hemojuvelin-Hemochromatosis Models

Mariateresa Pettinato, Mariam Aghajan, PhD, Violante Olivari, MSc, Alessandro Dulja, MSc, Antonella Nai, PhD, Jessica Bordini, PhD, Alessandro Campanella, PhD, Alessia Pagani, PhD, Shuling Guo, PhD, Clara Camaschella, MD, Laura Silvestri, PhD

Blood (2019) 134 (Supplement_1): 955.

https://doi.org/10.1182/blood-2019-126496

Published: 2019

Journal Articles

Targeting Transferrin Receptor 2: A Novel "Erythropoiesis-Stimulating Approach" in a Model of Anemia of Chronic Kidney Disease

Violante Olivari, MSc, Maria Rosa Lidonnici, PhD, Mariateresa Pettinato, Laura Silvestri, PhD, Giuliana Ferrari, PhD, Clara Camaschella, MD, Antonella Nai, PhD

Blood (2019) 134 (Supplement_1): 956.

https://doi.org/10.1182/blood-2019-125783

Published: 2019

Journal Articles

Exploring the Mechanisms of Thalassemic Erythropoiesis Improvement Caused By Bone Marrow Tfr2 Deletion

Antonella Nai, PhD, Irene Artuso, MSc, Maria Rosa Lidonnici, PhD, Sandro Altamura, PhD, Giacomo Mandelli, PhD, Mariateresa Pettinato, MSc, Martina U. Muckenthaler, PhD, Laura Silvestri, PhD, Giuliana Ferrari, PhD, Clara Camaschella, MD

Blood (2018) 132 (Supplement 1): 3624.

https://doi.org/10.1182/blood-2018-99-115835

Published: 2018

Journal Articles

Inhibiting the Immunophilin FKBP12: A Potential Therapeutic Approach to Iron Overload/Low Hepcidin Disorders

Mariateresa Pettinato, MSc, Mariam Aghajan, Alessandro Dulja, Antonella Nai, PhD, Violante Olivari, Jessica Bordini, MSc, Alessandro Campanella, PhD, Alessia Pagani, PhD, Shuling Guo, Clara Camaschella, MD, Laura Silvestri, PhD

Blood (2018) 132 (Supplement 1): 2333.

https://doi.org/10.1182/blood-2018-99-118112

Published: 2018

Journal Articles

Novel Insights Into Systemic Iron Regulation

Laura Silvestri, PhD, Alessia Pagani, PhD, Antonella Nai, PhD, Clara Camaschella, MD

Blood (2018) 132 (Supplement 1): SCI-1.

https://doi.org/10.1182/blood-2018-99-109518

Published: 2018

Journal Articles

The Macrophage Nuclear Receptor Coactivator 4 Counteracts Iron-Deficiency Anemia

Antonella Nai, PhD, Maria Rosa Lidonnici, Irene Artuso, MSc, Giorgia Federico, PhD, Giacomo Mandelli, Giuliana Ferrari, PhD, Clara Camaschella, MD, Francesca Carlomagno, MD, Laura Silvestri, PhD

Blood (2017) 130 (Supplement 1): 224.

https://doi.org/10.1182/blood.V130.Suppl_1.224.224

Published: 2017

Journal Articles

NCOA4 Links Iron Bioavailability to DNA Metabolism

Giorgia Federico, PhD, Roberto Bellelli, PhD, Antonella Nai, PhD, Laura Silvestri, PhD, Clara Camaschella, MD, Achille Iolascon, MD PhD, Massimo Santoro, MD, Francesca Carlomagno, MD

Blood (2017) 130 (Supplement 1): 223.

https://doi.org/10.1182/blood.V130.Suppl_1.223.223

Published: 2017

Journal Articles

Impairment in the Mesenchymal Bone-Marrow Niche of Beta-Thalassemia Patients and Association with Prolonged Iron Exposure

Stefania Crippa, PhD, Valeria Rossella, Biologist, Laura Silvestri, PhD, Annamaria Aprile, PhD, Samantha Scaramuzza, Silvia Rivis, maria Antonietta Avanzini, Marco Zecca, MD, Sarah Marktel, MD, Fabio Ciceri, MD, Alessandro Aiuti, MD, Giuliana Ferrari, PhD, Maria Ester Bernardo, MD PhD

Blood (2017) 130 (Supplement 1): 948.

https://doi.org/10.1182/blood.V130.Suppl_1.948.948

Published: 2017

Journal Articles

Transient Reduction of Transferrin Saturation Contributes to Hepcidin Inhibition Independently of Erfe in Mice Treated with Erythropoietin

Irene Artuso, MSc, Antonella Nai, PhD, Mariateresa Pettinato, MSc, Alessia Pagani, PhD, Chloe Latour, Benjamin Billore, Maria Rosa Lidonnici, Giacomo Mandelli, Giuliana Ferrari, Clara Camaschella, MD, Leon C. Kautz, PhD, Laura Silvestri, PhD

Blood (2017) 130 (Supplement 1): 174.

https://doi.org/10.1182/blood.V130.Suppl_1.174.174

Published: 2017

Journal Articles

Unraveling the Erythroid Function of Tfr2 in Beta-Thalassemia

Antonella Nai, PhD, Maria Rosa Lidonnici, PhD, Irene Artuso, BSc, Giacomo Mandelli, PhD, Mariateresa Pettinato, BSc, Laura Silvestri, PhD, Giuliana Ferrari, PhD, Clara Camaschella, MD

Blood (2016) 128 (22): 73.

https://doi.org/10.1182/blood.V128.22.73.73

Published: 2016

Journal Articles

A Novel Crosstalk Between Iron Homeostasis and mTOR Mediated By the Immunophilin FKBP12

Laura Silvestri, PhD, Silvia Colucci, Alessia Pagani, PhD, Irene Artuso, BSc, Mariatesera Pettinato, BSc, Antonella Nai, PhD, Clara Camaschella, MD

Blood (2016) 128 (22): 261.

https://doi.org/10.1182/blood.V128.22.261.261

Published: 2016

Journal Articles

Inactivation of Tmprss6 Hampers Hepcidin Inhibition By Erythroferrone through Upregulation of the BMP-SMAD Pathway

Laura Silvestri, PhD, Antonella Nai, PhD, Alessandro Campanella, PhD, Irene Artuso, BSc, Jessica Bordini, BSc, Clara Camaschella, MD

Blood (2015) 126 (23): 408.

https://doi.org/10.1182/blood.V126.23.408.408

Published: 2015

Journal Articles

Transferrin Receptor 2 and HFE Regulate Hepcidin Levels Independently of Bmp6 and Hemojuvelin

Céline Besson-Fournier, Chloé Latour, Ophélie Gourbeyre, Patricia Aguilar-Martinez, MD PhD, Laura Silvestri, PhD, Marie-Paule Roth, MD, Hélène Coppin, PhD

Blood (2014) 124 (21): 746.

https://doi.org/10.1182/blood.V124.21.746.746

Published: 2014

Journal Articles

Is Tmprss6 Required for Hepcidin Inhibition By Erythroferrone?

Laura Silvestri, PhD, Grazia Rita Gelsomino, Antonella Nai, PhD, Marco Rausa, Alessia Pagani, PhD, Clara Camaschella, MD

Blood (2014) 124 (21): 1347.

https://doi.org/10.1182/blood.V124.21.1347.1347

Published: 2014

Journal Articles

The Role Of Liver Endothelial Sinusoidal Cells In Iron-Mediated Bmp6 Regulation

Laura Silvestri, PhD, Marco Rausa, Antonella Nai, PhD, Alessia Pagani, PhD, Clara Camaschella, MD

Blood (2013) 122 (21): 177.

https://doi.org/10.1182/blood.V122.21.177.177

Published: 2013

NARROW

The Immunophilin FKBP12 Inhibits Hepcidin By Modulating BMP Type I-Type II Receptors Interaction and Ligand Responsiveness

Targeting the BMP Receptor Inhibitor FKBP12 to Upregulate Hepcidin in Wild-Type and Hemojuvelin-Hemochromatosis Models

Targeting Transferrin Receptor 2: A Novel "Erythropoiesis-Stimulating Approach" in a Model of Anemia of Chronic Kidney Disease

Exploring the Mechanisms of Thalassemic Erythropoiesis Improvement Caused By Bone Marrow Tfr2 Deletion

Inhibiting the Immunophilin FKBP12: A Potential Therapeutic Approach to Iron Overload/Low Hepcidin Disorders

Novel Insights Into Systemic Iron Regulation

The Macrophage Nuclear Receptor Coactivator 4 Counteracts Iron-Deficiency Anemia

NCOA4 Links Iron Bioavailability to DNA Metabolism

Impairment in the Mesenchymal Bone-Marrow Niche of Beta-Thalassemia Patients and Association with Prolonged Iron Exposure

Transient Reduction of Transferrin Saturation Contributes to Hepcidin Inhibition Independently of Erfe in Mice Treated with Erythropoietin

Unraveling the Erythroid Function of Tfr2 in Beta-Thalassemia

A Novel Crosstalk Between Iron Homeostasis and mTOR Mediated By the Immunophilin FKBP12

Inactivation of Tmprss6 Hampers Hepcidin Inhibition By Erythroferrone through Upregulation of the BMP-SMAD Pathway

Transferrin Receptor 2 and HFE Regulate Hepcidin Levels Independently of Bmp6 and Hemojuvelin

Is Tmprss6 Required for Hepcidin Inhibition By Erythroferrone?

The Role Of Liver Endothelial Sinusoidal Cells In Iron-Mediated Bmp6 Regulation

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