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Krystle Nomie
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Journal Articles

Radiation Therapy and Monocyte Activation in Large B-Cell Lymphoma Patients Treated with CAR T-Cell Therapy

Penny Q. Fang, Susan Y. Wu, Jillian R. Gunther, Alena Frank, Pavel Zemskiy, Aleksandr Zaitsev, Evgenii S Bolshakov, Anastasiya Terenteva, Krystle Nomie, Michelly Abreu, Karla Ow, Minifrida Santiago, Jaimole Varghese, Amy Ayers, Jared Henderson, Sairah Ahmed, Jason R. Westin, Christopher R. Flowers, Sattva S. Neelapu, Bouthaina S. Dabaja, Chelsea C. Pinnix, Paolo Strati
Journal: Blood
Blood (2024) 144 (Supplement 1): 4377.
https://doi.org/10.1182/blood-2024-203844
Published: 2024
Journal Articles

Use of Molecular Immune Signatures for Frontline Treatment Selection in Patients with Advanced Stage Follicular Lymphoma

Tony Z. Zhuang, Lei Feng, Dai Chihara, Chijioke Nze, Amy A. Ayers, Mansoor Noorani, James D. Ayres, Daniela E. Duenas, Kumudha Balakrishnan, Ekaterina Nesterenko, Mark Meerson, Ksenia Zornikova, Krystle Nomie, Nikita Kotlov, Nathan Fowler, Maria Alma Rodriguez, Sattva S. Neelapu, Christopher R. Flowers, Paolo Strati
Journal: Blood
Blood (2024) 144 (Supplement 1): 2982.
https://doi.org/10.1182/blood-2024-202654
Published: 2024
Journal Articles

Gene Expression-Based Classifier Reclassifies Burkitt Lymphoma, HGBL NOS, DLBCL NOS, and Double/Triple Hit Lymphomas into Subtypes with More Uniform Mutational and Microenvironment Landscapes and Treatment Response

Juan Pablo Alderuccio, Andrey Tyshevich, Daniel Cassidy, Catalina Amador, Ksenia Zornikova, Danil Ivanov, Laura Medina Andara, Dmitry Grachev, Asaad Trabolsi, Michele D. Stanchina, Alexander Nesmelov, Dan Morgenstern Kaplan, Konstantin Chernyshov, Nikita Kotlov, Craig H. Moskowitz, Alexander Bagaev, Krystle Nomie, Nathan H. Fowler, Jennifer Rose Chapman-Fredricks, Izidore S. Lossos
Journal: Blood
Blood (2024) 144 (Supplement 1): 2981.
https://doi.org/10.1182/blood-2024-200975
Published: 2024
Journal Articles

Genomic and Spatial Proteomic Characterization of the Microenvironment of Diffuse Large B-Cell Lymphoma in African American Patients

Michelle J. Lee, Kumudha Balakrishnan, Arman Petrosyants, Daniil Wiebe, Chijioke Nze, Neha Akkad, Amy Ayers, James D. Ayres, Timothy J. McDonnell, Pavel Zemskiy, Kiril Kriukov, Alexander Nesmelov, Ksenia Zornikova, Krystle Nomie, Alexander Sarachakov, Nikita Kotlov, Ankur Singh, Jean L. Koff, Christopher R. Flowers
Journal: Blood
Blood (2024) 144 (Supplement 1): 4348.
https://doi.org/10.1182/blood-2024-210184
Published: 2024
Journal Articles

Evaluating the Clinical Utility of Real-Time Comprehensive Whole Exome Sequencing and RNA-Seq for Patients with Diffuse Large B-Cell Lymphoma

Dai Chihara, Kumudha Balakrishnan, Gita Masand, Robert Andrew Harkins, Neha Akkad, Anna Novokreshchenova, Alexander Bagaev, Nikita Kotlov, Ekaterina Postovalova, Eduardo Shugaev-Mendosa, Yuliya Gracheva, Kelley Lauziere, Leznath Kaneunyenye, Brianna McKenna, Amber Berlinski, McKenna Walsh, Linnea Larson, Mariam Kotsinyan, Anna Samokhina, Sheila T Yong, Krystle Nomie, Nathan H. Fowler, Christopher R. Flowers, Jason R. Westin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4364.
https://doi.org/10.1182/blood-2024-209105
Published: 2024
Journal Articles

Acalabrutinib with Rituximab Is Highly Effective First Line Treatment for Older Patients with Mantle Cell Lymphoma

Preetesh Jain, Chi Young Ok, Jason R. Westin, Holly A Hill, Ranjit Nair, Swami P. Iyer, Ahmed Fetooh, Hun Ju Lee, Sairah Ahmed, Rashmi Kanagal-Shamanna, Fatima Z Jelloul, Luis Malpica, Yang Liu, Yijing Li, Lei Feng, Maria Badillo, Selvi Thirumurthi, Anita Deswal, Cezar Iliescu, Vinh Quang Nguyen, Anastasiia A. Bolshakova, Dmitry Tabakov, Michael G Goldberg, Andrey Tyshevich, Tatiana Vasileva, Daria Shavronskaya, Krystle Nomie, Guilin Tang, Keyur P. Patel, Francisco Vega, L. Jeffrey Medeiros, Christopher R. Flowers, Michael Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 3038.
https://doi.org/10.1182/blood-2024-206042
Published: 2024
Journal Articles

Tumor Genomics and Microenvironment Characterization of Diffuse Large B-Cell Lymphoma in Asian and Pacific Islander Patients

Michelle J. Lee, Kumudha Balakrishnan, Pavel Zemskiy, James D. Ayres, Timothy J. McDonnell, Neha Akkad, Kiril Kriukov, Arina Tkachuk, Ksenia Zornikova, Krystle Nomie, Aleksander Bagaev, Jean L. Koff, Christopher R. Flowers
Journal: Blood
Blood (2024) 144 (Supplement 1): 6209.
https://doi.org/10.1182/blood-2024-210739
Published: 2024
Journal Articles

Genomic and Transcriptomic Profiles of Blastoid and Pleomorphic Mantle Cell Lymphoma Are Distinct from Classic Histology Mantle Cell Lymphoma

Preetesh Jain, Holly A Hill, Chi Young Ok, Alexander Nesmalov, Vitaly Segodin, Dmitry Tabakov, Nikita Kotlov, Pavel Zemskiy, Eleonora Belykh, Krystle Nomie, Ahmed Fetooh, Rashmi Kanagal-Shamanna, Fatima Z Jelloul, Guilin Tang, Francisco Vega, Nathan Fowler, Christopher R. Flowers, Michael L. Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3001.
https://doi.org/10.1182/blood-2023-181319
Published: 2023
Journal Articles

Test-the-Test: Clinical Utility of Comprehensive Whole Exome Sequencing and RNA-Seq for Patients with Lymphoma

Dai Chihara, Kumudha Balakrishnan, Gita Masand, Anna Novokreshchenova, Alexander Bagaev, Nikita Kotlov, Ekaterina Postovalova, Eduardo Shugaev-Mendosa, Yuliya Gracheva, Anna Love, Krystle Nomie, Nathan Fowler, Christopher R. Flowers, Jason Westin
Journal: Blood
Blood (2023) 142 (Supplement 1): 7155.
https://doi.org/10.1182/blood-2023-189426
Published: 2023
Journal Articles

Immune-Depleted Tumor Microenvironment Signature Is Associated with BTK Inhibitor Resistance in Mantle Cell Lymphoma

Preetesh Jain, Krystle Nomie, Vitaly Segodin, Evgeniy Egorov, Yixin Yao, Lucy Navsaria, Holly Hill, Nikita Kotlov, Rashmi Kanagal-Shamanna, Chi Young Ok, Francisco Vega, Shaoying Li, Yuxuan Che, Yijing Li, Viktor Svekolkin, Alexander Bagaev, Felix Frenkel, Ravshan Attaulakhanov, Nathan H. Fowler, Christopher R. Flowers, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1321.
https://doi.org/10.1182/blood-2021-151416
Published: 2021
Journal Articles

Integration and Iteration: Using Advanced, High-Content Imaging and Single-Cell Gene Expression Analysis to Uncover Unique Aspects of Follicular Lymphoma Biology

Andrea J. Radtke, PhD, Arthur L. Shaffer, III, PhD, Stefania Pittaluga, MD PhD, Alexander Bagaev, MS, Nishant Thakur, PhD, Theresa Davies-Hill, BS, Olga Plotnikova, MS, Ilia Galkin, MS, Ekaterina Postovalova, PhD, Viktor Svekolkin, MS, Sergei Isaev, MS, Yaroslav Lozinsky, MS, Mark Meerson, MS, Arina Varlamova, MS, Pavel Ovcharov, MS, Margarita Polyakova, MD, Krystle Nomie, PhD, Ekaterina Nuzhdina, MS, Nikita Kotlov, MS, Maria Tsiper, PhD, Felix Frenkel, PhD, Ravshan Attaulakhanov, PhD, Nathan H Fowler, MD, Ziv Yaniv, PhD, Bradley C Lowekamp, PhD, Michael Kelly, PhD, Ezzat Dadkhah, PhD, Da Wei Huang, MD, Jagan R. Muppidi, MD PhD, Elaine S. Jaffe, MD, Wyndham H. Wilson, MD PhD, Louis M. Staudt, MD PhD, Ronald N. Germain, MD PhD, Mark Roschewski, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-142633
Published: 2020
Journal Articles

Single Cell Transcriptomic Evolution and Resistance Mechanisms of BTK and BCL-2 Inhibition in Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Shaojun Zhang, PhD, Junwei Lian, PhD, Yuanxin Wang, Rongjia Zhang, Yang Liu, PhD, Joseph McIntosh, BS, Guangchun Han, Ruiping Wang, PhD, David Santos, Maria Badillo, MSN, RN, OCN, CCRP, Angela Leeming, Zhihong Chen, Kimberly Hartig, John Bigcal, Hun Lee, MD, Raphael Eric Steiner, MD, Jorge Enrique Romaguera, MD, Preetesh Jain, MBBS,MDDM,PhD, Krystle Nomie, PhD, Andy Futreal, Linghua Wang, MDPhDMS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-140882
Published: 2020
Journal Articles

Analysis of Factors Predictive of Risk of Transformation and Time to Transformation in Patients (pts) with Mantle Cell Lymphoma - Cohort Study of 369 Patients

Preetesh Jain, MBBS,MDDM,PhD, Rashmi Kanagal-Shamanna, MD, Chi Young Ok, MD, Gonzalez-Pagan Omarya, Lucy Navsaria, MB BCh BAO, Graciela M. Nogueras González, MPH, Shaojun Zhang, PhD, Guangchun Han, Ahmad Ghorab, Prajwal Boddu, MD, F. B. Hagemeister, MD, Hun Ju Lee, MD, Krystle Nomie, PhD, Changying Jiang, PhD, Luis Fayad, MD, Jason R. Westin, MD, Loretta J. Nastoupil, MD MSc, Sairah Ahmed, MD, Swaminathan P. Iyer, MD, Richard E. Champlin, MD, Sattva S Neelapu, MD, Jorge Enrique Romaguera, MD, Nathan H. Fowler, MD, Guilin Tang, MD, Shaoying Li, MD, Keyur Patel, MD PhD, Selvi Thirumurthi, Pan Tinsu, Guofang Xu, MD, Linghua Wang, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1526.
https://doi.org/10.1182/blood-2019-125936
Published: 2019
Journal Articles

Identify AMPK-Mediated Autophagy and Oxphos As a Novel Metabolic Vulnerability for Targeted Therapy in Mantle Cell Lymphoma

Yixin Yao, PhD, Yang Liu, MD, Hui Zhang, Angela Leeming, Joseph Mitchell McIntosh, Preetesh Jain, MBBS,MDDM,PhD, Liang Zhang, MD PhD, Krystle Nomie, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1506.
https://doi.org/10.1182/blood-2019-126738
Published: 2019
Journal Articles

The Development of a Precision Medicine Platform to Overcome Ibrutinib Resistance in Mantle Cell Lymphoma

Yang Liu, MD, Shuangtao Zhao, PhD, Changying Jiang, PhD, Yixin Yao, PhD, Kelley Paige Murfin, MSPH, Hadley Grundman, Liang Zhang, MD PhD, Krystle Nomie, PhD, Linghua Wang, PhD, Michael Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1487.
https://doi.org/10.1182/blood-2019-131079
Published: 2019
Journal Articles

Non-Bcl2 Mutations Are Predominant in Patients (pts) with Venetoclax Resistant Mantle Cell Lymphoma (MCL) - Response and Clinical Outcomes in Ultra-Refractory MCL

Preetesh Jain, MBBS,MDDM,PhD, Shuangtao Zhao, PhD, Rashmi Kanagal-Shamanna, MD, Lucy Navsaria, MB BCh BAO, Holly Hill, Ankita Misra, Krystle Nomie, PhD, Changying Jiang, PhD, Yixin Yao, PhD, Liang Zhang, MD PhD, Loretta J. Nastoupil, MD MSc, F. B. Hagemeister, MD, Jason R. Westin, MD, Ranjit Nair, MD, Raphael Eric Steiner, MD, Onyeka Oriabure, Wendy Chen, Guilin Tang, MD, C. Cameron Yin, MD PhD, Keyur Patel, MD PhD, Jorge Enrique Romaguera, MD, Nathan H. Fowler, MD, Linghua Wang, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2815.
https://doi.org/10.1182/blood-2019-126175
Published: 2019
Journal Articles

BI-1206, a Monoclonal Antibody Against Fcγriib, Showed Superior Anti-Tumor Activity in an Ibrutinib-Venetoclax Dual Resistant PDX Model in Mantle Cell Lymphoma

Changying Jiang, PhD, Yang Liu, MD, Joseph Mitchell McIntosh, Angela Leeming, Rongjia Zhang, William Lee, Krystle Nomie, PhD, Ingrid Karlsson, PhD, Linda Mårtensson, PhD, Mathilda Kovacek, Ingrid Teige, PhD, Björn Frendéus, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2863.
https://doi.org/10.1182/blood-2019-126957
Published: 2019
Journal Articles

Genetically Defined Metabolic Targets Overcome Ibrutinib Resistance in Mantle Cell Lymphoma

Liang Zhang, MD PhD, Hui Guo, PhD, Hui Zhang, Yixin Yao, PhD, Yang Liu, MD, Shaojun Zhang, PhD, Lixin Rui, PhD, Linghua Wang, PhD, Krystle Nomie, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 395.
https://doi.org/10.1182/blood-2019-125934
Published: 2019
Journal Articles

Targeting PI3K and PLK1 to Overcome Ibrutinib-Venetoclax Resistance in Mantle Cell Lymphoma

Changying Jiang, PhD, Rongjia Zhang, Shaojun Zhang, PhD, William Lee, Shengjian Huang, PhD, Yang Liu, MD, Angela Leeming, Joseph Mitchell McIntosh, Preetesh Jain, MBBS,MDDM,PhD, Krystle Nomie, PhD, Linghua Wang, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4062.
https://doi.org/10.1182/blood-2019-128299
Published: 2019
Journal Articles

Frontline Treatment with Ibrutinib Plus Rituximab (IR) Followed By Short Course R-Hypercvad/MTX Is Extremely Potent and Safe in Patients (age ≤ 65 years) with Mantle Cell Lymphoma (MCL) - Results of Phase-II Window-1 Clinical Trial

Michael L. Wang, MD, Preetesh Jain, MBBS,MDDM,PhD, Hun Ju Lee, MD, F. B. Hagemeister, MD, Felipe Samaniego, MD, Jason R. Westin, MD, Loretta J. Nastoupil, MD MSc, Wendy Chen, Krystle Nomie, PhD, Shaojun Zhang, PhD, Omar Moghrabi, Shuangtao Zhao, PhD, Rashmi Kanagal-Shamanna, MD, Chi Young Ok, MD, Onyeka Oriabure, Graciela M. Nogueras González, MPH, Dayoung Jung, Lucy Navsaria, MB BCh BAO, Ann Uy, Archie Pedersen, Liang Zhang, MD PhD, Changying Jiang, PhD, Feng Lei, MS, Yixin Yao, PhD, Guofang Xu, MD, Nicolaus Wagner-Bartak, MD, Selvi Thirumurthi, David Santos, Guilin Tang, MD, Keyur Patel, MD PhD, C. Cameron Yin, MD PhD, Michelle Avellaneda, Maria Badillo, Luis Fayad, MD, Sattva S Neelapu, MD, Nathan H. Fowler, MD, Jorge Enrique Romaguera, MD, Linghua Wang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3987.
https://doi.org/10.1182/blood-2019-126044
Published: 2019