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Kevin M Slawin, MD
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Journal Articles

Dual-Switch CAR-T Cells: Orthogonal Molecular Switches to Control Activation and Elimination of CAR-T Cells to Target CD123 + Cancer

J. Henri Bayle, PhD, MyLinh T Duong, PhD, An Lu, Eva Morschl, PhD, Matthew R. Collinson-Pautz, PhD, Kelly L Sharp, Slawomir Szymanski, PhD, Mary E. Brandt, Kevin M. Slawin, MD, Steven Toler, PhD, Eric Yvon, S., Aaron Foster, David M. Spencer
Journal: Blood
Blood (2017) 130 (Supplement 1): 3184.
https://doi.org/10.1182/blood.V130.Suppl_1.3184.3184
Published: 2017
Journal Articles

MyD88/CD40 Enhanced CD19-Specific CAR-T Cells Maintain Therapeutic Efficacy Following Resolution of Cytokine-Related Toxicity Using Inducible Caspase-9

Aaron Foster, Pei-Yi Lin, PhD, An Lu, Wei-Chun Chang, PhD, Nicholas Shinners, Mariam Khalil, Jeannette Crisostomo, Aruna Mahendravada, Kevin M. Slawin, MD, David M. Spencer
Journal: Blood
Blood (2017) 130 (Supplement 1): 4615.
https://doi.org/10.1182/blood.V130.Suppl_1.4615.4615
Published: 2017
Journal Articles

Inducible MyD88/CD40 (iMC) Enhances Proliferation and Survival of Tumor-Specific TCR-Modified T Cells and Improves Anti-Tumor Efficacy in Myeloma

Tsvetelina Pentcheva-Hoang, PhD, David Torres, Tania Rodriguez, PhD, Ana Korngold, PhD, An Lu, Jeannette Crisostomo, Annemarie Moseley, MD PhD, Lorenz Jahn, Mirjam H.M. Heemskerk, PhD, Kevin M Slawin, MD, David M Spencer, PhD, Aaron E Foster, PhD
Journal: Blood
Blood (2016) 128 (22): 4550.
https://doi.org/10.1182/blood.V128.22.4550.4550
Published: 2016
Journal Articles

Inducible MyD88/CD40 (iMC) Costimulation Provides Ligand-Dependent Tumor Eradication By CD123-Specific Chimeric Antigen Receptor T Cells

Aaron E Foster, PhD, MyLinh Duong, PhD, An Lu, Peter Chang, PhD, Aruna Mahendravada, Nicholas Shinners, PhD, Kevin M Slawin, MD, J. Henri Bayle, PhD, David M Spencer, PhD
Journal: Blood
Blood (2016) 128 (22): 4551.
https://doi.org/10.1182/blood.V128.22.4551.4551
Published: 2016
Journal Articles

Inducible MyD88/CD40 Enhances Proliferation and Survival of PRAME-Specific TCR-Engineered T Cells and Increases Anti-Tumor Effects in Myeloma

Tsvetalina Hoang, PhD, Aaron Foster, PhD, Jeannette Crisostomo, An Lu, Annemarie Moseley, MDPhD, Mirjam H.M. Heemskerk, PhD, Kevin M Slawin, MD, David M Spencer, PhD
Journal: Blood
Blood (2015) 126 (23): 1886.
https://doi.org/10.1182/blood.V126.23.1886.1886
Published: 2015
Journal Articles

Inducible MyD88/CD40 Allows Rimiducid-Dependent Activation to Control Proliferation and Survival of Chimeric Antigen Receptor-Modified T Cells

Aaron Foster, PhD, Aruna Mahendravada, Nicholas P Shinners, PhD, Peter Chang, PhD, An Lu, Eva Morschl, PhD, Joanne Shaw, PhD, Sunandan Saha, PhD, Kevin M Slawin, MD, David M Spencer, PhD
Journal: Blood
Blood (2015) 126 (23): 4295.
https://doi.org/10.1182/blood.V126.23.4295.4295
Published: 2015
Journal Articles

Expression of MyD88/CD40 Drives In Vivo Activation and Proliferation of Chimeric Antigen Receptor-Modified T Cells That Can be Effectively Regulated By Inducible Caspase-9

Aaron Foster, PhD, Peter Chang, PhD, Pei-Yi Lin, PhD, Jeannette Crisostomo, Aruna Mahendravada, An Lu, Mariam Khalil, Sunandan Saha, PhD, Joanne Shaw, PhD, Eva Morschl, PhD, Kevin M Slawin, MD, David M Spencer, PhD
Journal: Blood
Blood (2015) 126 (23): 851.
https://doi.org/10.1182/blood.V126.23.851.851
Published: 2015