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Kenneth J. Livak, PhD
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Journal Articles

Local and Systemic Effects of Immune Checkpoint Blockade on Relapsed Myeloid Malignancies Following Allogeneic Hematopoietic Stem Cell Transplantation

Livius Penter, Yi Zhang, PhD, Alexandra Savell, BS, Srinika Ranasinghe, PhD, Teddy Huang, BS, Nicoletta Cieri, MD PhD, Satyen H Gohil, PhD MB, BS, Wandi Zhang, BS, Shuqiang Li, PhD, Robert Zeiser, PhD, Haesook T. Kim, PhD, Kenneth J. Livak, PhD, Jerome Ritz, MD, Donna S. Neuberg, ScD, Robert J. Soiffer, MD, X. Shirley Liu, PhD, Matthew S. Davids, MD, Pavan Bachireddy, MD, Catherine J. Wu, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
https://doi.org/10.1182/blood-2020-139487
Published: 2020
Journal Articles

RPS15 and TP53 Co-Mutation Drives B Cell Malignancy through Altered Translation and MYC Activation in a Murine Model

Catherine Gutierrez, Tamara Ouspenskaia, PhD, Doris Fu, Peyton Waddicor, B.S., Anat Biran, PhD, Aviv Liani, Gregory Lazarian, PharmD, Elisa Ten Hacken, PhD, Elizabeth Witten, Fara Faye Regis, BS, Heather Joyal, Leah Billington, BA, Fabienne Lucas, MDPhD, Mei Zheng, Blake Tye, PhD, Maria Hernandez-Sanchez, PhD, Miguel Quijada Álamo, MSc, Shuqiang Li, PhD, Binyamin A. Knisbacher, PhD, Ziao Lin, BS, Aziz Al'Khafaji, PhD, Lili Wang, MDPhD, Kenneth J. Livak, PhD, Donna S. Neuberg, ScD, Florence Cymbalista, MD PhD, Gad Getz, PhD, Stirling Churchman, PhD, Ruben D. Carrasco, MD PhD, Sichen Shao, PhD, Aviv Regev, PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-138900
Published: 2020
Journal Articles

Genetic Determinants and Evolutionary History of Richter's Syndrome

Erin Michelle Parry, MD PhD, Romain Guieze, MD, Ignaty Leshchiner, PhD, Daniel Rosebrock, Bria Persaud, Camilla K Lemvigh, MSc, Eugen Tausch, MD, Matthew S. Davids, MD, Johannes Bloehdorn, MD, Christof Schneider, MD, Liudmila Elagina, Aina Zurita Martinez, Amaro Taylor-Weiner, PhD, Nitin Jain, MD, William G. Wierda, MD PhD, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, Julien Broséus, Florence Cymbalista, MD PhD, Neil E. Kay, MD, Kenneth J. Livak, PhD, Shuqiang Li, PhD, Teddy Huang, BS, Noelia Purroy, MD PhD, Annabelle J Anandappa, MD, Stacey M. Fernandes, BS, Filippo Utro, PhD, Kahn Rhrissorrakrai, PhD, Chaya Levovitz, MD PhD, Brian P Danysh, PhD, Kara Slowik, Sameer A. Parikh, MD, Jennifer R Brown, MD PhD, Laxmi Parida, PhD, Donna S. Neuberg, ScD, Stephan Stilgenbauer, MD, Gad Getz, PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
https://doi.org/10.1182/blood-2020-139456
Published: 2020
Journal Articles

IKZF3 Overexpression Phenocopies Gain-of-Function Mutation in Chronic Lymphocytic Leukemia

Shanye Yin, PhD, Gregory Lazarian, PharmD, Elisa Ten Hacken, PhD, Tomasz Sewastianik, PhD, Satyen Gohil, BSc, MBBS, MRCP, FRCPath, Shuqiang Li, PhD, Laura Z. Rassenti, PhD, Leah Billington, BA, Elizabeth Witten, Teddy Huang, BS, Kenneth J. Livak, PhD, Donna S. Neuberg, ScD, Fanny Baran-Marszak, MD PhD, Thomas J. Kipps, MD PhD, Florence Cymbalista, MD PhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9.
https://doi.org/10.1182/blood-2020-137085
Published: 2020
Journal Articles

Multiplexed CRISPR In Vivo Editing of CLL Loss-of-Function Lesions Models Transformation of Chronic Lymphocytic Leukemia into Richter's Syndrome

Elisa Ten Hacken, PhD, Tomasz Sewastianik, PhD, Robert A. Redd, MS, Geoffrey Fell, MS, Mohamed Uduman, PhD, Michaela Gruber, MD PhD, Shanye Yin, PhD, Kendell Clement, PhD, Erin Michelle Parry, MD PhD, Shuqiang Li, PhD, Maria Hernandez-Sanchez, PhD, Leah Billington, BA, Elizabeth Witten, Kaitlyn J Baranowski, Lili Wang, MDPhD, Luca Pinello, PhD, Kenneth J. Livak, PhD, Donna S. Neuberg, ScD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-137130
Published: 2020
Journal Articles

Interrogation of Individual CLL Loss-of-Function Lesions By CRISPR In Vivo Editing Reveals Common and Unique Pathway Alterations

Elisa Ten Hacken, PhD, Shanye Yin, PhD, Kendell Clement, PhD, Robert A. Redd, MS, Maria Hernandez-Sanchez, PhD, Shuqiang Li, PhD, Michaela Gruber, MD PhD, Heather Joyal, Geoffrey Fell, MS, Shu Wang, Jose Jacob, James Flynn, David Ruff, Keith W. Jones, Lili Wang, MD PhD, Donna S Neuberg, ScD, Luca Pinello, PhD, Kenneth J. Livak, PhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 684.
https://doi.org/10.1182/blood-2019-127673
Published: 2019
Journal Articles

Lineage Tracing in Chronic Lymphocytic Leukemia Reveals Clones with Stable Gene Expression States That Differentially Respond to Therapy

Catherine Gutierrez, Aziz Al'Khafaji, B.S., Eric Brenner, B.S., Russell Durrett, B.S., M.S., Kaitlyn Johnson, B.S., M.S., Wandi Zhang, MD, Shuqiang Li, PhD, Kenneth J. Livak, PhD, Donna S Neuberg, ScD, Amy Brock, PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1229.
https://doi.org/10.1182/blood-2019-129303
Published: 2019