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Journal Articles

Knock-Ins of Type-2 Calr Mutants Cause Myeloproliferative Neoplasm (MPN)-like Hematopoiesis in Mice

Keiji Minakawa, Koki Ueda, MD PhD, Osamu Nakajima, Tetsuro Yokokawa, MD, Yusuke Kinishima, MD, Tomofumi Misaka, MD PhD, Kazuei Ogawa, MD PhD, Takayuki Ikezoe, MD PhD, Yasuchika Takeishi, MD PhD, Kazuhiko Ikeda, MD PhD

Blood (2019) 134 (Supplement_1): 2964.

https://doi.org/10.1182/blood-2019-124575

Published: 2019

Journal Articles

HMGA2 mRNA Expression in Patients with Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)

Keiji Minakawa, Koki Ueda, MD PhD, Akiko Shichishima, MD PhD, Hiroshi Ohkawara, MD PhD, Kazuei Ogawa, MD PhD, Takayuki Ikezoe, MD PhD, Yayoi Shikama, MD PhD, Kenneth E Nollet, MD PhD, Kazuhiko Ikeda, MD PhD

Blood (2018) 132 (Supplement 1): 4384.

https://doi.org/10.1182/blood-2018-99-114399

Published: 2018

Journal Articles

A Critical Role of Growth Arrest-Specific Gene 6-Mer Axis in the Pathogenesis of Endothelial Damage Contributing to Thrombotic Microangiopathy Associated with Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation

Miki Furukawa, MD PhD, Wang Xintao, MD PhD, Hiroshi Ohkawara, MD PhD, Masahiko Fukatsu, MD, Lobna Alkebsi, PhD, Hideyoshi Noji, MD PhD, Kazuei Ogawa, MD PhD, Takayuki Ikezoe, MD PhD

Blood (2018) 132 (Supplement 1): 4520.

https://doi.org/10.1182/blood-2018-99-112816

Published: 2018

Journal Articles

Functional Impairment of Hematopoietic Stem/Progenitor Cells By Loss of Uhrf2 in Mice

Takahiro Sano, MD, Koki Ueda, MDPhD, Kazuhiko Ikeda, MD PhD, Kazuei Ogawa, MD PhD, Tsutomu Mori, MD PhD, Takayuki Ikezoe, MD, PhD

Blood (2017) 130 (Supplement 1): 3759.

https://doi.org/10.1182/blood.V130.Suppl_1.3759.3759

Published: 2017

Journal Articles

Autocrine and Paracrine Interactions Between Multiple Myeloma Cells and Bone Marrow Stromal Cells By Growth Arrest-Specific Gene 6 Crosstalk with Interleukin-6

Miki Furukawa, MD, Ohkawara Hiroshi, MD PhD, Kazuei Ogawa, MD PhD, Kazuhiko Ikeda, MD PhD, Ueda Koki, MD PhD, Akiko Shichishima-Nakamura, MD PhD, Emi Ito, PhD, Jun-ichi Imai, PhD, Yuka Yanagisawa, PhD, Reiko Honma, PhD, Shinya Watanabe, MD PhD, Satoshi Waguri, MD PhD, Takayuki Ikezoe, MD PhD, Yasuchika Takeishi, MD PhD

Blood (2016) 128 (22): 5606.

https://doi.org/10.1182/blood.V128.22.5606.5606

Published: 2016

Journal Articles

HMGA2 Orchestrates the Tumorgenesis of Myeloproliferative Neoplasms (MPN) in Corporation with JAK2 V617F

Koki Ueda, MD PhD, Kazuhiko Ikeda, MD PhD, Takayuki Ikezoe, MD PhD, Kazuei Ogawa, MD PhD, Yuko Hashimoto, MD PhD, Kayo Harada-Shirado, Hiroshi Ohkawara, MD PhD, Norio Komatsu, MD PhD, Kotaro Shide, MD PhD, Kazuya Shimoda, MD, PhD, Shuhei Koide, PhD, Motohiko Oshima, PhD, Atsushi Iwama, MD PhD, Yasuchika Takeishi, MD PhD

Blood (2016) 128 (22): 796.

https://doi.org/10.1182/blood.V128.22.796.796

Published: 2016

Journal Articles

Expression of HMGA2 Collaborates with JAK2V617F to Progress Myeloproliferative Neoplasms

Koki Ueda, MD PhD, Kazuhiko Ikeda, MD PhD, Kazuei Ogawa, MD PhD, Akiko Shichishima-Nakamura, MD PhD, Kotaro Shide, MD PhD, Kazuya Shimoda, MD PhD, Yuko Hashimoto, MD PhD, Philip J Mason, PhD, Monica Bessler, MD PhD, Yasuchika Takeishi, MD PhD

Blood (2015) 126 (23): 482.

https://doi.org/10.1182/blood.V126.23.482.482

Published: 2015

Journal Articles

Autocrine and Paracrine Regulatory Mechanisms of Growth Arrest-Specific Gene 6 Contribute to Disease Progression of Multiple Myeloma

Miki Furukawa, MD, Hiroshi Ohkawara, MD PhD, Kazuhiko Ikeda, MD PhD, Emi Ito, PhD, Jun-ichi Imai, PhD, Yuka Yanagisawa, PhD, Reiko Honma, PhD, Shinya Watanabe, MD PhD, Satoshi Waguri, MD PhD, Kazuei Ogawa, MD PhD, Yasuchika Takeishi, MD PhD

Blood (2015) 126 (23): 4179.

https://doi.org/10.1182/blood.V126.23.4179.4179

Published: 2015

Journal Articles

Velocity of Early BCR-ABL Transcript Elimination As an Optimized Predictor of Deep Molecular Response in Chronic Myeloid Leukemia Patients in Chronic Phase on Treatment with Dasatinib

Kazunori Murai, MD PhD, Kohei Yamaguchi, MD, Shigeki Ito, MD PhD, Tomoaki Akagi, Kazuei Ogawa, MD PhD, Inomata Mitsue, Kuniaki Meguro, Reiko Watanabe, MD PhD, Takuto Miyagishima, MD, PhD, Kentaro Wakasa, Motohiro Shindo, MD PhD, Yasuhiko Tsukushi, MD PhD, Kohmei Kubo, MD, PhD, Koji Oba, PhD, Junichi Sakamoto, MDPhD, Yoji Ishida, MD, PhD

Blood (2015) 126 (23): 4052.

https://doi.org/10.1182/blood.V126.23.4052.4052

Published: 2015

Journal Articles

Excessive TNF-α Production Results from Reduction of c-Fos Via Aberrant Expression of Mir-34a in Neutrophils from Myelodysplastic Syndrome Patients

Yayoi Shikama, MD PhD, Meiwan Cao, MD, Tomoyuki Ono, Michiko Anzai, Hideyoshi Noji, MD PhD, Xiaomin Feng, MD PhD, Hideo Kimura, MD PhD, Kazuei Ogawa, MD PhD, Kazuhiko Ikeda, MD PhD, Yasuchika Takeishi, MD PhD, Junko Kimura, MD PhD

Blood (2015) 126 (23): 1650.

https://doi.org/10.1182/blood.V126.23.1650.1650

Published: 2015

Journal Articles

Dysregulation of the Let-7/HMGA2 Axis with Methylation of p16 Promoter As a Possible Target of Histone Deacetylase Inhibitor in Myeloproliferative Neoplasms

Kayo Shirado Harada, MD, Kazuhiko Ikeda, MD PhD, Kazuei Ogawa, MD PhD, Hiroshi Ohkawara, MD PhD, Yasuchika Takeishi, MD PhD

Blood (2014) 124 (21): 3213.

https://doi.org/10.1182/blood.V124.21.3213.3213

Published: 2014

Journal Articles

Impact of Red Blood Cell and Platelet Transfusions at Early after Engraftment on Outcome of Allogeneic Hematopoietic Stem Cell Transplantation

Kazuhiko Ikeda, MD PhD, Yumiko Mashimo, MD, Hiroshi Ohkawara, MD PhD, Hiroshi Takahashi, MD, Akiko Shichishima-Nakamura, MD PhD, Kayo Shirado Harada, MD, Miki Furukawa, MD, Hideyoshi Noji, MD PhD, Kazuei Ogawa, MD PhD, Hitoshi Ohto, MD PhD, Yasuchika Takeishi, MD PhD

Blood (2014) 124 (21): 2480.

https://doi.org/10.1182/blood.V124.21.2480.2480

Published: 2014

Journal Articles

Clinical Efficacy and Safety Of Dasatinib For Newly Diagnosed Chronic Myeloid Leukemia In Chronic Phase In Japan

Kohei Yamaguchi, M.D., Kazunori Murai, M.D., Ph.D., Shigeki Ito, M.D., Ph.D., Tomoaki Akagi, M.D., Ph.D., Kazuei Ogawa, M.D., Ph.D., Kuniaki Meguro, M.D., Ph.D., Mitsue Inomata, M.D., Reiko Watanabe, M.D., Ph.D., Takuto Miyagishima, M.D., Kentaro Wakasa, M.D., Motohiro Shindo, M.D., Ph.D., Yasuhiko Tsukushi, M.D., Kohmei Kubo, M.D., Ph.D., Yoji Ishida, M.D., Ph.D.

Blood (2013) 122 (21): 1493.

https://doi.org/10.1182/blood.V122.21.1493.1493

Published: 2013

Journal Articles

The Role Of Deregulated HMGA2 Expression With Promoter Methylation Of p16 In Myeloproliferative Neoplasms

Kayo Shirado Harada, MD, Kazuhiko Ikeda, MD, PhD, Kazuei Ogawa, MD, PhD, Hideyoshi Noji, MD, PhD, Hideo Kimura, MD, PhD, Tatsuyuki Kai, MD, PhD, Soji Morishita, PhD, Norio Komatsu, MD, PhD, Yasuchika Takeishi, MD, PhD

Blood (2013) 122 (21): 1606.

https://doi.org/10.1182/blood.V122.21.1606.1606

Published: 2013

Journal Articles

Ineffective Erythropoiesis With Increased Neutrophils In Old Mice Overexpressing Hmga2 cDNA

Kazuhiko Ikeda, MD, PhD, Philip J. Mason, Kayo Shirado Harada, MD, Kazuei Ogawa, MD, PhD, Monica Bessler, Yasuchika Takeishi, MD, PhD

Blood (2013) 122 (21): 2469.

https://doi.org/10.1182/blood.V122.21.2469.2469

Published: 2013

Journal Articles

The Prospective Analysis Of Clinical Efficacy and Adverse Events In Chronic Myeloid Leukemia In Chronic Phase (CML-CP) Patients With Imatinib Resistance Or Intolerance, Evaluated By European Leukemia Net (ELN) 2013 Criteria

Kazunori Murai, M.D., Ph.D., Tomoaki Akagi, M.D., Ph.D., Kenji Shimosegawa, MD, Kenichi Ishizawa, MD, PhD, Tomohiro Sugawara, MD, Hisayuki Yokoyama, MD, PhD, Hideyoshi Noji, MD, PhD, Kazuei Ogawa, M.D., Ph.D., Katsushi Tajima, MD, PhD, Koji Oba, PhD, Junichi Sakamoto, MD, PhD, Koumei Kubo, MD, PhD, Hisashi Sakamaki, MD, PhD, Hideo Harigae, MD, PhD, Yoji Ishida, M.D., Ph.D.

Blood (2013) 122 (21): 4027.

https://doi.org/10.1182/blood.V122.21.4027.4027

Published: 2013

Journal Articles

Pharmacokinetic (PK) and Pharmacodynamic (PD) Study Of Dasatinib In Chronic Phase Of Newly Diagnosed Chronic Myeloid Leukemia (CML-CP)

Blood (2013) 122 (21): 4031.

https://doi.org/10.1182/blood.V122.21.4031.4031

Published: 2013

Journal Articles

Expression of Let-7 Micro RNAs in Transgenic Mice Overexpressing Truncated Hmga2

Kazuhiko Ikeda, MD, PhD, Kayo Harada, MD, Kazuei Ogawa, MD, PhD, Philip J Mason, PhD, Monica Bessler, MD, PhD, Yasuchika Takeishi, MD, PhD

Blood (2012) 120 (21): 3470.

https://doi.org/10.1182/blood.V120.21.3470.3470

Published: 2012

Journal Articles

Efficacy and Safety of Dasatinib in Chronic Myeloid Leukemia Patients in Chronic Phase (CML-CP) with Imatinib Resistance or Intolerance

Tomoaki Akagi, MD, PhD, Kazunori Murai, MD, PhD, Kenji Shimosegawa, MD, Kenichi Ishizawa, MD, PhD, Tomohiro Sugawara, MD, Hisayuki Yokoyama, MD, PhD, Hideyoshi Noji, MD, PhD, Kazuei Ogawa, MD, Katsusi Tazima, MD, PhD, Koji Ooba, MD, Junichi Sakamoto, MD, PhD, Kubo Koumei, MD, PhD, Hisashi Sakamaki, MD, Hideo Harigae, MD, PhD, Yoji Ishida, MD, PhD

Blood (2011) 118 (21): 4444.

https://doi.org/10.1182/blood.V118.21.4444.4444

Published: 2011

Journal Articles

Outcome After First Relapse In Adult Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

Shinichi Kako, MD, Heiwa Kanamori, MD, Naoki Kobayashi, MD, Akio Shigematsu, MD, Yasuhito Nannya, MD, Mika Nakamae, M.D., Ph.D, Kazuyuki Shigeno, MD, Kazumi Suzukawa, MD, Masahiro Takeuchi, MD, Motohiro Tsuzuki, MD, Kensuke Usuki, MD, Kazuo Hatanaka, MD, Kazuei Ogawa, MD, Kinuko Mitani, MD, Yuichiro Nawa, MD, Yoshihiro Hatta, MD, Ishikazu Mizuno, MD, Yoshinobu Kanda, MD

Blood (2011) 118 (21): 3084.

https://doi.org/10.1182/blood.V118.21.3084.3084

Published: 2011

NARROW

Knock-Ins of Type-2 Calr Mutants Cause Myeloproliferative Neoplasm (MPN)-like Hematopoiesis in Mice

HMGA2 mRNA Expression in Patients with Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)

A Critical Role of Growth Arrest-Specific Gene 6-Mer Axis in the Pathogenesis of Endothelial Damage Contributing to Thrombotic Microangiopathy Associated with Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation

Functional Impairment of Hematopoietic Stem/Progenitor Cells By Loss of Uhrf2 in Mice

Autocrine and Paracrine Interactions Between Multiple Myeloma Cells and Bone Marrow Stromal Cells By Growth Arrest-Specific Gene 6 Crosstalk with Interleukin-6

HMGA2 Orchestrates the Tumorgenesis of Myeloproliferative Neoplasms (MPN) in Corporation with JAK2 V617F

Expression of HMGA2 Collaborates with JAK2V617F to Progress Myeloproliferative Neoplasms

Autocrine and Paracrine Regulatory Mechanisms of Growth Arrest-Specific Gene 6 Contribute to Disease Progression of Multiple Myeloma

Velocity of Early BCR-ABL Transcript Elimination As an Optimized Predictor of Deep Molecular Response in Chronic Myeloid Leukemia Patients in Chronic Phase on Treatment with Dasatinib

Excessive TNF-α Production Results from Reduction of c-Fos Via Aberrant Expression of Mir-34a in Neutrophils from Myelodysplastic Syndrome Patients

Dysregulation of the Let-7/HMGA2 Axis with Methylation of p16 Promoter As a Possible Target of Histone Deacetylase Inhibitor in Myeloproliferative Neoplasms

Impact of Red Blood Cell and Platelet Transfusions at Early after Engraftment on Outcome of Allogeneic Hematopoietic Stem Cell Transplantation

Clinical Efficacy and Safety Of Dasatinib For Newly Diagnosed Chronic Myeloid Leukemia In Chronic Phase In Japan

The Role Of Deregulated HMGA2 Expression With Promoter Methylation Of p16 In Myeloproliferative Neoplasms

Ineffective Erythropoiesis With Increased Neutrophils In Old Mice Overexpressing Hmga2 cDNA

The Prospective Analysis Of Clinical Efficacy and Adverse Events In Chronic Myeloid Leukemia In Chronic Phase (CML-CP) Patients With Imatinib Resistance Or Intolerance, Evaluated By European Leukemia Net (ELN) 2013 Criteria

Pharmacokinetic (PK) and Pharmacodynamic (PD) Study Of Dasatinib In Chronic Phase Of Newly Diagnosed Chronic Myeloid Leukemia (CML-CP)

Expression of Let-7 Micro RNAs in Transgenic Mice Overexpressing Truncated Hmga2

Efficacy and Safety of Dasatinib in Chronic Myeloid Leukemia Patients in Chronic Phase (CML-CP) with Imatinib Resistance or Intolerance

Outcome After First Relapse In Adult Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

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