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Journal Articles

The Rationale, Design, and Baseline Characteristics of a Phase 2 Study to Evaluate the Safety and Efficacy of Ropeginterferon Alfa-2b (P1101) in Japanese Patients with Polycythemia Vera for Whom the Current Standard of Care Is Difficult to Apply

Keita Kirito, MD, Kazuya Shimoda, MD PhD, Katsuto Takenaka, MD PhD, Albert Qin, MD PhD, Oleh Zagrijtschuk, MD, Toshiaki Sato, MD PhD, Narihisa Miyachi, Hiroaki Kawase, Katsuya Yonezu, Norio Komatsu, MD PhD

Blood (2020) 136 (Supplement 1): 24–25.

https://doi.org/10.1182/blood-2020-142504

Published: 2020

Journal Articles

Escape Hematopoiesis By HLA-B5401-Lacking Hematopoietic Stem Progenitor Cells in Male Patients with Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Mahmoud Ibrahim Elbadry, MD, Hiroki Mizumaki, MD, Luis Espinoza, MD PhD, Noriharu Nakagawa, MD, Kazuhisa Chonabayashi, MD PhD, Yoshinori Yoshida, MD PhD, Takamasa Katagiri, PhD, Yoshitaka Zaimoku, MD PhD, Tatsuya Imi, MD, Nguyen Thi Mai Anh, MD, Yoichi Fujii, MD, Seishi Ogawa, MD PhD, Katsuto Takenaka, MD PhD, Koichi Akashi, MD PhD, Shinji Nakao, MD PhD

Blood (2018) 132 (Supplement 1): 3855.

https://doi.org/10.1182/blood-2018-99-113756

Published: 2018

Journal Articles

Comparison of Outcomes of Allogeneic Hematopoietic Cell Transplantation for Primary Myelofibrosis Among Stem Cell Source Groups

Makoto Murata, MD PhD, Katsuto Takenaka, MD PhD, Naoyuki Uchida, MD PhD, Yukiyasu Ozawa, Kazuteru Ohashi, MD PhD, Sung-Won Kim, MD PhD, Kazuhiro Ikegame, MD PhD, Yoshiko Atsuta, MD PhD, Makoto Hirokawa, MD PhD, Takahiro Fukuda, Takeshi Kondo, MD PhD

Blood (2018) 132 (Supplement 1): 3466.

https://doi.org/10.1182/blood-2018-99-114745

Published: 2018

Journal Articles

A Heterozygous Mutation of G-Protein-Coupled Receptor 25 in a Family with Inherited Thrombocytopenia and Thrombosis

Jun Yamanouchi, MD PhD, Yuichi Ikeda, MD, Takaaki Hato, MD PhD, Masaki Yasukawa, MD PhD, Katsuto Takenaka, MD PhD

Blood (2018) 132 (Supplement 1): 1151.

https://doi.org/10.1182/blood-2018-99-110275

Published: 2018

Journal Articles

Clinical Outcomes of Patients with Primary Myelofibrosis in Japan: A Nationwide Survey over a 17-Year Study Period

Katsuto Takenaka, MD PhD, Kazuya Shimoda, MD, PhD, Naoyuki Uchida, MDPhD, Taizo Shimomura, MD PhD, Koji Nagafuji, MD PhD, Tadakazu Kondo, MD PhD, Hirohiko Shibayama, MDPhD, Takehiko Mori, MD PhD, Kensuke Usuki, MD PhD, Taichi Azuma, MDPhD, Yutaka Tsutsumi, MD PhD, Junji Tanaka, MD PhD, Hitomi Dairaku, Keitaro Matsuo, MDPhD, Keiya Ozawa, MD PhD, Mineo Kurokawa, MD, PhD, Shunya Arai, MD, PhD, Koichi Akashi, MD PhD

Blood (2016) 128 (22): 3126.

https://doi.org/10.1182/blood.V128.22.3126.3126

Published: 2016

Journal Articles

Introduction of Macrophage Tolerance By Human SIRPA Knock-in Enhances Peripheral Reconstitution of Human Hematopoiesis in Xenotransplantation Model

Fumiaki Jinnouchi, MD, Katsuto Takenaka, MD PhD, Chika Iwamoto, PhD, Takuji Yamauchi, MD PhD, Ayano Yurino, MD, Takuya Nunomura, MD, Yoshikane Kikushige, MD PhD, Koji Kato, MD PhD, Toshihiro Miyamoto, MD PhD, Koichi Akashi, MD PhD

Blood (2016) 128 (22): 29.

https://doi.org/10.1182/blood.V128.22.29.29

Published: 2016

Journal Articles

Comparative Analysis of Tyrosine Kinase Inhibitors-Related Pulmonary Hypertension in the Patients Treated By Imatinib, Dasatinib and Nilotinib

Mariko Minami, MD, Toshihiro Miyamoto, MD PhD, Takeshi Arita, MD PhD, Tomohiko Kamimura, MD PhD, Junichiro Yuda, MD, Yoshikane Kikushige, MD PhD, Yasuo Mori, MDPhD, Goichi Yoshimoto, MD PhD, Kenjiro Kamezaki, MD PhD, Koji Kato, MD PhD, Motoaki Shiratsuchi, MDPhD, Katsuto Takenaka, MD PhD, Hiromi Iwasaki, MDPhD, Satoshi Yamasaki, MD PhD, Tsuyoshi Muta, MD PhD, Kazuki Tanimoto, MD PhD, Ryosuke Ogawa, MD PhD, Tetsuya Eto, MD PhD, Koichi Akashi, MD PhD

Blood (2015) 126 (23): 1583.

https://doi.org/10.1182/blood.V126.23.1583.1583

Published: 2015

Journal Articles

Prior Use of Mogamulizumab to Allogenic Hematopoietic Stem Cell Transplantation Induces Severe Acute Graft-Versus-Host Disease

Blood (2015) 126 (23): 1940.

https://doi.org/10.1182/blood.V126.23.1940.1940

Published: 2015

Journal Articles

Introduction of the Kit Mutation into Immunodeficient Mice Enables Xenogeneic Reconstitution of Human Megakaryocyte-Erythroid Hematopoietic System

Yurino Ayano, MD, Takuji Yamauchi, MD PhD, Takuya Nunomura, MD, Yasufumi Uehara, MD, Fumiaki Jinnouchi, MD, Shinya Daitoku, MD, Yuya Kunisaki, MD PhD, Katsuto Takenaka, MD PhD, Koichi Akashi, MD PhD

Blood (2015) 126 (23): 1153.

https://doi.org/10.1182/blood.V126.23.1153.1153

Published: 2015

Journal Articles

Mutations of Calreticulin in Myeloproliferative Neoplasms Contribute to Disease Progression Not through Inhibition of Phagocytosis, but through Enhanced Proliferation Production of Myeloid Myelo-Erythroid Progenitor Cells

Shinya Daitoku, MD, Katsuto Takenaka, MD PhD, Takuji Yamauchi, MD PhD, Koichi Akashi, MD PhD

Blood (2014) 124 (21): 4594.

https://doi.org/10.1182/blood.V124.21.4594.4594

Published: 2014

Journal Articles

Fibrotic Tissues In Human Primary Myelofibrosis With JAK2 V617F Are Developed Clonally From Malignant Hematopoietic Stem Cells

Takuji Yamauchi, MD, PhD, Takahiro Shima, MD, Katsuto Takenaka, MD, PhD, Toshihiro Miyamoto, MD, Koichi Akashi, MD, PhD

Blood (2013) 122 (21): 4106.

https://doi.org/10.1182/blood.V122.21.4106.4106

Published: 2013

Journal Articles

The Expansion Of CML Clones Initiates At The CMP Stage, and Is Associated With The Down-Regulation Of IRF8 and GFI1

Kohta Miyawaki, MD, Hirotake Kusumoto, MD, Tadafumi Iino, MD, Kentaro Kohno, MD, Hirofumi Tsuzuki, Takahiro Shima, MD, Yoshikane Kikushige, MD, PhD, Yojiro Arinobu, MD, PhD, Katsuto Takenaka, MD, PhD, Toshihiro Miyamoto, MD, Hiromi Iwasaki, MD, PhD, Koichi Akashi, MD, PhD

Blood (2013) 122 (21): 1477.

https://doi.org/10.1182/blood.V122.21.1477.1477

Published: 2013

Journal Articles

BALB/c- Specific L29V Polymorphism In SIRPA Determines The Efficient Engraftment Of Human Hematopoiesis In Xenogeneic Model

Chika Iwamoto, Katsuto Takenaka, MD, PhD, Shingo Urata, MD, Takahiro Shima, MD, Takuji Yamauchi, MD, PhD, Takuro Kuriyama, MD, PhD, Shinya Daitoku, MD, Yasuyuki Saito, MD, PhD, Katsuhiko Itoh, MD, PhD, Junji Kishimoto, PhD, Daisuke Kohda, PhD, Takashi Matozaki, MD, PhD, Koichi Akashi, MD, PhD

Blood (2013) 122 (21): 337.

https://doi.org/10.1182/blood.V122.21.337.337

Published: 2013

Journal Articles

Establishment of a New Immunodeficient Mouse Line Harboring NOD-Type Sirpa with Highly-Efficient Human Hematopoietic Cell Engraftment.

Takuji Yamauchi, M.D., Katsuto Takenaka, MD, PhD, Shingo Urata, M.D., Takahiro Shima, MD, Yoshikane Kikushige, MD, PhD, Takahito Tokuyama, MD, Chika Iwamoto, Toshihiro Miyamoto, MD, PhD, Koichi Akashi, MD, PhD.

Blood (2012) 120 (21): 2301.

https://doi.org/10.1182/blood.V120.21.2301.2301

Published: 2012

Journal Articles

Hemophagocytic Lymphohistiocytosis Is Caused by Engulfment of Hematopoietic Stem Cells by Macrophages Through Stem Cell-Specific Suppression of CD47 Under Influence of Cytokine Deregulation

Takuro Kuriyama, MD, Katsuto Takenaka, MD, PhD, Kentaro Kohno, MD, Goichi Yoshimoto, MD, PhD, Junji Kishimoto, PhD, Yasunobu Abe, MD, PhD, Toshihiro Miyamoto, MD, PhD, Koichi Akashi, MD, PhD.

Blood (2011) 118 (21): 522.

https://doi.org/10.1182/blood.V118.21.522.522

Published: 2011

Journal Articles

The Efficient Engraftment of Human Hematopoiesis in the Balb/c Strain Is Mounted by Balb/c-Specific SIRPA Polymorphism That Enhances Binding Affinity to Human CD47,

Chika Iwamoto, Katsuto Takenaka, MD, PhD, Shingo Urata, M.D., Takahiro Shima, MD, Katsuhiko Itoh, M.D., PhD, Junji Kishimoto, PhD, Toshihiro Miyamoto, MD, PhD, Takashi Matozaki, MD, PhD, Koichi Akashi, MD, PhD.

Blood (2011) 118 (21): 4008.

https://doi.org/10.1182/blood.V118.21.4008.4008

Published: 2011

Journal Articles

Elevated Leukocyte Alkaline Phosphatase Scores Induced by Jak2 V617F Mutation

Seido Oku, MD, Katsuto Takenaka, MD, PhD, Takashi Kumano, MD, Takuro Kuriyama, MD, Shingo Urata, MD, Kotaro Shide, MD, PhD, Haruko Shimoda, MD, PhD, Hiromi Iwasaki, MD, PhD, Toshihiro Miyamoto, MD, PhD, Takanori Teshima, MD, PhD, Koji Nagafuji, MD, PhD, Kazuya Shimoda, MD, PhD, Koichi Akashi, MD, PhD

Blood (2008) 112 (11): 5244.

https://doi.org/10.1182/blood.V112.11.5244.5244

Published: 2008

Journal Articles

Expression of V617F JAK2 in Mice Leads to MPD Mimicking Human ET, Idiopahtic Myelofibrosis, and PV.

Kotaro Shide, MD, Haruko K. Shimoda, MD, PhD, Takashi Kumano, MD, Kennosuke Karube, MD, PhD, Takuro Kameda, MD, Seido Oku, MD, Katsuto Takenaka, MD, PhD, Keiko Suzuki, MD, PhD, Youko Kubuki, MD, PhD, Mine Harada, MD, PhD, Kazuya Shimoda, MD, PhD

Blood (2007) 110 (11): 2531.

https://doi.org/10.1182/blood.V110.11.2531.2531

Published: 2007

Journal Articles

Identification of a New Genetic Determinant Controlling Human Hematopoietic Stem Cell Engraftment.

Katsuto Takenaka, MD, PhD, Tatiana K. Prasolava, PhD, Jean C.Y. Wang, MD PhD, Steven M. Mortin-Toth, Sam Khalouei, Olga I. Gan, PhD, John E. Dick, PhD, Jayne S. Danska, PhD

Blood (2007) 110 (11): 175.

https://doi.org/10.1182/blood.V110.11.175.175

Published: 2007

NARROW

The Rationale, Design, and Baseline Characteristics of a Phase 2 Study to Evaluate the Safety and Efficacy of Ropeginterferon Alfa-2b (P1101) in Japanese Patients with Polycythemia Vera for Whom the Current Standard of Care Is Difficult to Apply

Escape Hematopoiesis By HLA-B5401-Lacking Hematopoietic Stem Progenitor Cells in Male Patients with Acquired Aplastic Anemia

Comparison of Outcomes of Allogeneic Hematopoietic Cell Transplantation for Primary Myelofibrosis Among Stem Cell Source Groups

A Heterozygous Mutation of G-Protein-Coupled Receptor 25 in a Family with Inherited Thrombocytopenia and Thrombosis

Clinical Outcomes of Patients with Primary Myelofibrosis in Japan: A Nationwide Survey over a 17-Year Study Period

Introduction of Macrophage Tolerance By Human SIRPA Knock-in Enhances Peripheral Reconstitution of Human Hematopoiesis in Xenotransplantation Model

Comparative Analysis of Tyrosine Kinase Inhibitors-Related Pulmonary Hypertension in the Patients Treated By Imatinib, Dasatinib and Nilotinib

Prior Use of Mogamulizumab to Allogenic Hematopoietic Stem Cell Transplantation Induces Severe Acute Graft-Versus-Host Disease

Introduction of the Kit Mutation into Immunodeficient Mice Enables Xenogeneic Reconstitution of Human Megakaryocyte-Erythroid Hematopoietic System

Mutations of Calreticulin in Myeloproliferative Neoplasms Contribute to Disease Progression Not through Inhibition of Phagocytosis, but through Enhanced Proliferation Production of Myeloid Myelo-Erythroid Progenitor Cells

Fibrotic Tissues In Human Primary Myelofibrosis With JAK2 V617F Are Developed Clonally From Malignant Hematopoietic Stem Cells

The Expansion Of CML Clones Initiates At The CMP Stage, and Is Associated With The Down-Regulation Of IRF8 and GFI1

BALB/c- Specific L29V Polymorphism In SIRPA Determines The Efficient Engraftment Of Human Hematopoiesis In Xenogeneic Model

Establishment of a New Immunodeficient Mouse Line Harboring NOD-Type Sirpa with Highly-Efficient Human Hematopoietic Cell Engraftment.

Hemophagocytic Lymphohistiocytosis Is Caused by Engulfment of Hematopoietic Stem Cells by Macrophages Through Stem Cell-Specific Suppression of CD47 Under Influence of Cytokine Deregulation

The Efficient Engraftment of Human Hematopoiesis in the Balb/c Strain Is Mounted by Balb/c-Specific SIRPA Polymorphism That Enhances Binding Affinity to Human CD47,

Elevated Leukocyte Alkaline Phosphatase Scores Induced by Jak2 V617F Mutation

Expression of V617F JAK2 in Mice Leads to MPD Mimicking Human ET, Idiopahtic Myelofibrosis, and PV.

Identification of a New Genetic Determinant Controlling Human Hematopoietic Stem Cell Engraftment.

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