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Kathrin M. Bernt, MD
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Journal Articles

SWI/SNF Dysregulation through a Prion-like Domain Causes AML

Simone S Riedel, PhD, Alexandra Lenard, BS, Kevin Nestler, BS, Congcong Lu, PhD, Hongbo Xie, PhD, Benjamin A Garcia, PhD, Kathrin M. Bernt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2512.
https://doi.org/10.1182/blood-2019-129280
Published: 2019
Journal Articles

Tight Regulation of H3K79 Methylation Levels in KMT2A -Rearranged AML

Molly C. Kingsley, BS, Simone Stefanie Riedel, PhD, Hongbo Michael Xie, PhD, Sally P. Stabler, MD, Taylor Pastuer, BA, Kathrin M. Bernt, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3884.
https://doi.org/10.1182/blood-2018-99-114784
Published: 2018
Journal Articles

Menin Is a Therapeutic Target in MN1 High Leukemia

Clara Libbrecht, MD, Simone Stefanie Riedel, PhD, Jessica Haladyna, BA,MS, Kathrin M. Bernt, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 758.
https://doi.org/10.1182/blood-2018-99-115551
Published: 2018
Journal Articles

The Role of Gata2 in Murine Models of Acute Myeloid Leukemia

Taylor Yamauchi, B.A., Etienne Danis, PhD, Xi Zhang, B.A., Simone Riedel, PhD, Hua Huang, MD, PhD, Kathrin M Bernt, MD, Tobias Neff, MD
Journal: Blood
Blood (2016) 128 (22): 1516.
https://doi.org/10.1182/blood.V128.22.1516.1516
Published: 2016
Journal Articles

Epigenetics Directing Therapy in Acute Lymphocytic Leukemia: Emerging Roles and New Therapies

Kathrin M Bernt, MD
Journal: Blood
Blood (2015) 126 (23): SCI-36.
https://doi.org/10.1182/blood.V126.23.SCI-36.SCI-36
Published: 2015
Journal Articles

Meningeoma-1 Cooperates with MLL and DOT1L to Induce Leukemia

Simone Riedel, PhD, Jessica Haladyna, BA, Brett Stevens, Craig T Jordan, PhD, Daniel Pollyea, MD MS, Scott A. Armstrong, MD PhD, Qi Wei, PhD, Patricia Ernst, PhD, Tobias Neff, MD, Kathrin M Bernt, MD
Journal: Blood
Blood (2015) 126 (23): 2428.
https://doi.org/10.1182/blood.V126.23.2428.2428
Published: 2015
Journal Articles

Histone Profiling in Leukemia Using LC-MS/MS

Gina South, MD, Jessica Haladyna, BA, Kirk Hansen, PhD, Kathrin M Bernt, MD
Journal: Blood
Blood (2014) 124 (21): 2202.
https://doi.org/10.1182/blood.V124.21.2202.2202
Published: 2014
Journal Articles

MDR1 Mediated Drug Resistance to a Histone Methyltansferase Inhibitor (KMT)

Jessica Haladyna, BA, Taylor Yamauchi, BA, Tobias Neff, MD, Kathrin M Bernt, MD
Journal: Blood
Blood (2014) 124 (21): 3622.
https://doi.org/10.1182/blood.V124.21.3622.3622
Published: 2014
Journal Articles

Targeting Meningeoma-1 Driven AML through Epigenetic Modulation of the Cell of Origin

Simone Riedel, PhD, Kathrin M Bernt, MD, Jessica Haladyna, BA, Matthew Bezzant, Brett Stevens, PhD, Daniel A. Pollyea, MD MS, Amit U. Sinha, PhD, Scott A. Armstrong, MD PhD, Qi Wei, PhD, Craig T. Jordan, PhD, Tobias Neff, MD
Journal: Blood
Blood (2014) 124 (21): 838.
https://doi.org/10.1182/blood.V124.21.838.838
Published: 2014
Journal Articles

Context Dependent Role of Polycomb Repressive Complex 2 in Acute Leukemia

Etienne Danis, PhD, Taylor Yamauchi, BA, Kristen Echanique, BS, Jessica Haladyna, BA, Huafeng Xie, PhD, Nan Zhu, PhD, Simone Riedel, PhD, Kathrin M Bernt, MD, Stuart H. Orkin, MD, Scott A. Armstrong, MD PhD, Tobias Neff, MD
Journal: Blood
Blood (2014) 124 (21): 610.
https://doi.org/10.1182/blood.V124.21.610.610
Published: 2014
Journal Articles

MLL-AF6 Mediated Transformation Is Dependent On the H3K79 Methyl-transferase Dot1l

Aniruddha J Deshpande, Liying Chen, Maurizio Fazio, Amit U. Sinha, Kathrin M Bernt, MD, Deepti Banka, Stuart Dias, Edward J Olhava, PhD, Scott R Daigle, Victoria M Richon, PhD, Roy M Pollock, PhD, Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3502.
https://doi.org/10.1182/blood.V120.21.3502.3502
Published: 2012
Journal Articles

The Interaction Between DOT1L and AF10 Is Required for H3K79 Dimethylation and MLL-AF9 Leukemia

Aniruddha J Deshpande, Liying Chen, Kathrin M Bernt, MD, Stuart Dias, Deepti Banka, Amit U. Sinha, David Chen, Natalie Punt, James E. Bradner, M.D., Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 401.
https://doi.org/10.1182/blood.V120.21.401.401
Published: 2012
Journal Articles

Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor

Roy M Pollock, PhD, Scott R Daigle, Edward J Olhava, PhD, Carly A Therkelsen, Christina R Majer, Jeffrey Song, Christina J Allain, Christopher J Sneeringer, L. Danielle Johnston, Margaret Porter Scott, PhD, Lei Jin, PhD, Kevin W Kuntz, PhD, Richard Chesworth, DPhil, Mikel P Moyer, PhD, Kathrin M Bernt, MD, Scott Armstrong, MD, PhD, Robert A Copeland, PhD, Victoria M Richon, PhD
Journal: Blood
Blood (2010) 116 (21): 780.
https://doi.org/10.1182/blood.V116.21.780.780
Published: 2010
Journal Articles

Demonstration of a Role for Dot1l In MLL -Rearranged Leukemia Using a Conditional Loss of Function Model

Kathrin M Bernt, MD, Nan Zhu, PhD, Joerg Faber, M.D., Natalie Punt, Roy M Pollock, PhD, Victoria M Richon, PhD, Andrew L. Kung, MD, PhD, Scott Armstrong, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 62.
https://doi.org/10.1182/blood.V116.21.62.62
Published: 2010