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Karen Vanhoorelbeke, PhD
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Journal Articles

Anti-CUB1 or Anti-Spacer Antibodies That Increase ADAMTS13 Activity Act By Allosterically Enhancing Metalloprotease Domain Function

An-Sofie Schelpe, Anastasis Petri, Nele Vandeputte, Hans Deckmyn, PhD, Simon F De Meyer, PhD, James TB Crawley, PhD, Karen Vanhoorelbeke, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 23.
https://doi.org/10.1182/blood-2018-99-117061
Published: 2018
Journal Articles

Open ADAMTS13 Conformation in Immune-Mediated Thrombotic Thrombocytopenic Purpura Is Induced By Anti-ADAMTS13 Autoantibodies and Corresponds with an Ongoing ADAMTS13 Pathology

Elien Roose, PhD, An-Sofie Schelpe, Edwige Tellier, György Sinkovits, MD, Gilles Kaplanski, MD, Maelle Le Besnerais, Ilaria Mancini, PhD, Nele Vandeputte, Aline Vandenbulcke, Inge Pareyn, J. J. Voorberg, PhD, Andreas Greinacher, MD, Ygal Benhamou, MD, Hans Deckmyn, PhD, Rob FIjnheer, MD, Zoltan Prohászka, MD Prof, Flora Peyvandi, MD PhD, Paul Coppo, MD PhD, Simon F De Meyer, PhD, Agnès Veyradier, Sr., MD PhD, Karen Vanhoorelbeke, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 222.
https://doi.org/10.1182/blood-2018-99-113762
Published: 2018
Journal Articles

Phylogenetic Analysis Identifies a Subset of ADAMTS13 Domains That Are Highly Conserved and Essential for Allosteric Regulation

Joshua Muia, PhD, Jian Zhu, PhD, Suellen Greco, DVM, Karen Vanhoorelbeke, PhD, Louis Deforche, PhD, Lisa Westfield, Garima Tyagi, PhD, J. Evan Sadler, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1385.
https://doi.org/10.1182/blood.V128.22.1385.1385
Published: 2016
Journal Articles

The Hunt for the "Minimal" Structure of a Functional ADAMTS13: Study of Deletion Mutations of ADAMTS13 By Small-Angle X-Ray Scattering

Jian Zhu, PhD, Joshua Muia, PhD, Louis Deforche, PhD, Karen Vanhoorelbeke, PhD, Niraj H. Tolia, PhD, J. Evan Sadler, MD PhD
Journal: Blood
Blood (2016) 128 (22): 254.
https://doi.org/10.1182/blood.V128.22.254.254
Published: 2016
Journal Articles

Drug Inhibition of GPIb.

Hans Deckmyn, PhD, Simon F. De Meyer, PhD, Karen Vanhoorelbeke, PhD
Journal: Blood
Blood (2009) 114 (22): SCI-38.
https://doi.org/10.1182/blood.V114.22.SCI-38.SCI-38
Published: 2009
Journal Articles

Phenotypic Correction of von Willebrand Disease Type 3 Blood-Derived Endothelial Cells with Lentiviral Vectors Expressing von Willebrand Factor.

Simon F. De Meyer, Karen Vanhoorelbeke, PhD, Marinee K. Chuah, PhD, Inge Pareyn, Veerle Gillijns, Robert P. Hebbel, MD, Hans Deckmyn, PhD, Thierry Vandendriessche, PhD
Journal: Blood
Blood (2005) 106 (11): 5522.
https://doi.org/10.1182/blood.V106.11.5522.5522
Published: 2005