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Journal Articles

Novel evidence shows that intracellular complement (complosome) expressed in hematopoietic stem cell progenitor cells regulates hematopoiesis at both the mitochondrial and cellular metabolism levels.

Magdalena Kucia, Justyna Jarczak, Michalina Kazek, Emilia Waraksa-Zasada, Patrycja Kieszek, Mariusz Ratajczak

Blood (2025) 146 (Supplement 1): 3155.

https://doi.org/10.1182/blood-2025-3155

Published: 2025

Journal Articles

New evidence indicates that the NLRP3 inflammasome in hematopoietic stem and progenitor cells (HSPCs) maintains proper mitochondrial electron transport chain function and affects both cellular trafficking and metabolism through a gasdermin pore-mediated, alarmin-release-dependent mechanism

Magdalena Kucia, Michalina Kazek, Justyna Jarczak, Emilia Waraksa-Zasada, Patrycja Kieszek, Mariusz Ratajczak

Blood (2025) 146 (Supplement 1): 2314.

https://doi.org/10.1182/blood-2025-2314

Published: 2025