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Evolution Directed Gene Engineering (EDGE) Identifies Single Amino Acid Substitutions in FVIII with Six-Fold Increased in Vitro and In Vivo Activity

Lucas Van Gorder, Reilly Peng, Julia Chau, Ben J Samelson-Jones
Journal: Blood
Blood (2023) 142 (Supplement 1): 21.
https://doi.org/10.1182/blood-2023-178106
Published: 2023