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Journal Articles

Divergent Effects of Notch Signaling On Leukemia Stem Cells and Hematopoietic Stem Cells.

Mark Y Chiang, MD, PhD, Olga Shestova, Ph.D., M. Eden Childs, B.A., Candice Romany, Jon Aster, MD, PhD, Warren S. Pear, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 395.
https://doi.org/10.1182/blood.V114.22.395.395
Published: 2009
Journal Articles

A Regulatory Network Between Notch and AKT Signaling Pathways Differentially Controls Megakaryocyte Development From Hematopoietic Stem or Committed Progenitor Cells.

Melanie G Cornejo, Stephen M Sykes, Cristina Lo Celso, Zuzana Tothova, Jon Aster, MD, PhD, Ronald A DePinho, MD, David T Scadden, MD, D. Gary Gilliland, MD, PhD, Thomas Mercher, Ph.D
Journal: Blood
Blood (2009) 114 (22): 384.
https://doi.org/10.1182/blood.V114.22.384.384
Published: 2009
Journal Articles

Expression-Based Screen Identifies the Calcium Channel Antagonist Bepridil as a Notch1 Modulator in T-ALL.

Giovanni Roti, MD, Kenneth N. Ross, PhD, Adolfo A. Ferrando, MD, PhD, Stephen C Blacklow, M.D., Ph.D., Jon Aster, MD, PhD, Kimberly Stegmaier, MD
Journal: Blood
Blood (2009) 114 (22): 366.
https://doi.org/10.1182/blood.V114.22.366.366
Published: 2009
Journal Articles

Synergistic Killing of Leukemic Cells by Small Molecule Inhibitors of the Pim Protein Kinases and Inactivators of Additional Signal Transduction Pathways.

Yingwei Lin, MD, PhD, Zanna M Beharry, PhD., Elizabeth G Hill, Jin H. Song, Wenxue Wang, Zuping Xia, Zhenhua Zhang, Peter D. Aplan, MD, Jon Aster, MD, PhD, Charles D Smith, PhD, Andrew Kraft, MD
Journal: Blood
Blood (2009) 114 (22): 409.
https://doi.org/10.1182/blood.V114.22.409.409
Published: 2009
Journal Articles

C-Myc, but Not Akt, Can Substitute for Notch in Lymphomagenesis.

Mark Y Chiang, MD, PhD, M. Eden Childs, B.A., Candice Romany, Olga Shestova, Ph.D., Jon Aster, MD, PhD, Warren S. Pear, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 7.
https://doi.org/10.1182/blood.V114.22.7.7
Published: 2009
Journal Articles

Hematopoietic Stem Cell Defects in Novel Fanconi Anemia Mouse Models

Kalindi Parmar, PhD, Jung Min Kim, PhD, Akiko Shimamura, MD, PhD, Anna Stuckert, Mary K DeLoach, Kaya Zhu, Peter M. Mauch, MD, Jeffery Kutok, MD, PhD, Jon Aster, MD, PhD, Koichi Akashi, MD, PhD, D. Gary Gilliland, MD, PhD, Alan D. D’Andrea, MD
Journal: Blood
Blood (2008) 112 (11): 440.
https://doi.org/10.1182/blood.V112.11.440.440
Published: 2008
Journal Articles

Runx1 Is Required for Notch-Induced Specification of Megakaryocyte Development from Early Hematopoietic Stem and Progenitor Cells

Melanie G Cornejo, Thomas Mercher, Ph.D, Joseph D. Growney, PhD, Jonathan Jesneck, Ivan Maillard, MD, PhD, Warren S. Pear, MD, PhD, Jon Aster, MD, PhD, D. Gary Gilliland, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1370.
https://doi.org/10.1182/blood.V112.11.1370.1370
Published: 2008
Journal Articles

Notch Signaling Induces Megakaryocytic Cell Fate.

Thomas Mercher, PhD, Melanie Cornejo, Christopher Sears, PhD, Thomas Kindler, MD PhD, Sandra Moore, Jon Aster, MD PhD, D. Gary Gilliland, MD PhD
Journal: Blood
Blood (2007) 110 (11): 200.
https://doi.org/10.1182/blood.V110.11.200.200
Published: 2007
Journal Articles

Transcriptional Regulatory Networks Downstream of NOTCH1 in T-Cell Acute Lymphoblastic Leukemia.

Teresa Palomero, PhD, Duncan T. Odom, PhD, Adam Margolin, Jon Aster, MD, Andrea Califano, PhD, Richard A. Young, PhD, A. Thomas Look, MD, Adolfo A. Ferrando, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 740.
https://doi.org/10.1182/blood.V106.11.740.740
Published: 2005