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John A Zuris
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Journal Articles

A Bicistronic Vector Expressing CD16 and a Membrane Bound IL-15 Construct in iPSC Derived NK Cells Increased Cytotoxicity and Persistence

Alexander G Allen, Rithu Pattali, Kaitlyn M Izzo, Jared A Getgano, Kevin M Wasko, Laura C Blaha, John A Zuris, Kate Zhang, Mark S Shearman, Kai-Hsin Chang
Journal: Blood
Blood (2021) 138 (Supplement 1): 4809.
https://doi.org/10.1182/blood-2021-153258
Published: 2021
Journal Articles

EDIT-301: An Experimental Autologous Cell Therapy Comprising Cas12a-RNP Modified mPB-CD34+ Cells for the Potential Treatment of SCD

Edouard De Dreuzy, PhD, Jack Heath, John A Zuris, PhD, Patricia Sousa, Ramya Viswanathan, Sean Scott, Jen Da Silva, Terence Ta, PhD, Stacy Capehart, PhD, Tongyao Wang, Cecilia Fernandez, PhD, Vic E Myer, PhD, Charles F Albright, PhD, Christopher J Wilson, PhD, Sandra Teixeira, PhD, Kai-Hsin Chang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4636.
https://doi.org/10.1182/blood-2019-130256
Published: 2019
Journal Articles

Comparative Studies Reveal Robust HbF Induction By Editing of HBG1/2 Promoters or BCL11A Erythroid-Enhancer in Human CD34+ Cells but That BCL11A Erythroid-Enhancer Editing Is Associated with Selective Reduction in Erythroid Lineage Reconstitution in a Xenotransplantation Model

Kai-Hsin Chang, PhD, Minerva Sanchez, Jack Heath, Edouard deDreuzy, PhD, Scott Haskett, MS, Abigail Vogelaar, Kiran Gogi, Jen Da Silva, Tongyao Wang, Andrew Sadowski, Gregory Gotta, Jamaica Siwak, Ramya Viswanathan, Katherine Loveluck, Hoson Chao, Eric Tillotson, Aditi Chalishazar, MS, Abhishek Dass, Frederick Ta, Emily Brennan, Diana Tabbaa, Eugenio Marco, PhD, John A Zuris, PhD, Deepak Reyon, PhD, Meltem Isik, PhD, Ari Friedland, PhD, Terence Ta, PhD, Fred Harbinski, Georgia Giannoukos, PhD, Sandra Teixeira, PhD, Christopher J Wilson, PhD, Charlie Albright, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 409.
https://doi.org/10.1182/blood-2018-99-114780
Published: 2018
Journal Articles

Expanding CRISPR Genome Editing Strategies in Hematopoietic Stem and Progenitor Cells for the Treatment of Hematologic Diseases

Edouard deDreuzy, PhD, Aditi Chalishazar, MS, Jack Heath, Carrie M Margulies, PhD, John Labella, Ramya Viswanathan, Katherine Loveluck, KaiHsin Chang, PhD, Hariharan Jayaram, PhD, John A Zuris, PhD, Vic E Myer, PhD, Charlie Albright, PhD, Cecilia Cotta-Ramusino, PhD, Jennifer L Gori, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4619.
https://doi.org/10.1182/blood.V130.Suppl_1.4619.4619
Published: 2017