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Johannes L. Roesel
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Journal Articles

The Midostaurin (PKC412) Metabolite CGP52421 Shows Little Growth-Inhibitory Activity Against Against Neoplastic Mast Cells but Retains Inhibitory Effects on IgE-Dependent Activation and Histamine Release

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Barbara Peter, D.V.M., Katharina Blatt, M.Sc., Gabriele Stefanzl, Emir Hadzijusufovic, DVM, Catherine Dutreix, Stefan H Gross, Johannes L Roesel, Peter Valent, M.D.
Journal: Blood
Blood (2011) 118 (21): 1417.
https://doi.org/10.1182/blood.V118.21.1417.1417
Published: 2011
Journal Articles

Fingolimod (FTY720) Inhibits BCR-ABL Signaling Allosterically by Binding to the Myristate Binding Site

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Paul W. Manley, Ph. D., Sandra W. Cowan-Jacob, Robert Cozens, Gabriele Fendrich, Wolfgang Jahnke, Johannes L Roesel, Doriano Fabbro
Journal: Blood
Blood (2011) 118 (21): 2746.
https://doi.org/10.1182/blood.V118.21.2746.2746
Published: 2011
Journal Articles

Leukemogenic Tyrosine Kinases Inhibit PKM2 to Promote the Warburg Effect and Tumor Growth

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Taro Hitosugi, PhD, Sumin Kang, PhD, Matthew Vander Heiden, MD/PhD, Tea-wook Chung, PhD, Shannon Elf, Katherine Lythgoe, Shaozhong Dong, PhD, Sagar Lonial, MD, Xu Wang, PhD, Georgia Chen, PhD, Jianxin Xie, PhD, Ting-Lei Gu, PhD, Roberto Polakiewicz, PhD, Johannes L. Roesel, PhD, Titus Boggon, PhD, Fadlo Khuri, MD, D. Gary Gilliland, MD, PhD, Lewis Cantley, PhD, Jonathan L. Kaufman, MD, Jing Chen, PhD
Journal: Blood
Blood (2010) 116 (21): 3142.
https://doi.org/10.1182/blood.V116.21.3142.3142
Published: 2010